KEGG   PATHWAY: rse02010
Entry
rse02010                    Pathway                                
Name
ABC transporters - Ralstonia pseudosolanacearum FQY_4
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
rse02010  ABC transporters
rse02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Ralstonia pseudosolanacearum FQY_4 [GN:rse]
Gene
F504_1378  cysP; Sulfate and thiosulfate binding protein CysP [KO:K23163]
F504_1387  cysT; Sulfate transport system permease protein CysT [KO:K02046]
F504_1388  cysW; Sulfate transport system permease protein CysW [KO:K02047]
F504_1389  cysA; Sulfate and thiosulfate import ATP-binding protein CysA [KO:K02045] [EC:7.3.2.3]
F504_2046  ABC-type tungstate transport system, periplasmic binding protein [KO:K05772]
F504_2528  ABC-type tungstate transport system, permease protein [KO:K05773]
F504_2529  ABC-type tungstate transport system, ATP-binding protein [KO:K06857] [EC:7.3.2.6]
F504_402  Nitrate ABC transporter, nitrate-binding protein [KO:K15576]
F504_401  Nitrate ABC transporter, permease protein [KO:K15577]
F504_400  Nitrate ABC transporter, ATP-binding protein [KO:K15578] [EC:7.3.2.4]
F504_1380  Alkanesulfonates-binding protein [KO:K15553]
F504_4847  ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic component [KO:K15553]
F504_3441  ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic component [KO:K15553]
F504_1224  ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic component [KO:K15553]
F504_4979  ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic component [KO:K15553]
F504_1382  Alkanesulfonates transport system permease protein [KO:K15554]
F504_4978  tauC; Taurine transport system permease protein TauC [KO:K15554]
F504_1226  Alkanesulfonates transport system permease protein [KO:K15554]
F504_1383  ssuB; Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB [KO:K15555] [EC:7.6.2.14]
F504_4977  tauB; Taurine transport ATP-binding protein TauB [KO:K15555] [EC:7.6.2.14]
F504_1225  ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [KO:K15555] [EC:7.6.2.14]
F504_3557  Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA [KO:K02020]
F504_4641  modB; Molybdenum transport system permease protein ModB [KO:K02018]
F504_4642  modC; Molybdenum transport ATP-binding protein ModC [KO:K02017] [EC:7.3.2.5]
F504_2898  ABC-type Fe3 transport system, periplasmic component [KO:K02012]
F504_2902  Putative ABC transporter, periplasmmic iron binding protein precursor [KO:K02012]
F504_2903  Ferric iron ABC transporter, permease protein [KO:K02011]
F504_2904  small molecule transporter [KO:K02010] [EC:7.2.2.7]
F504_2458  L-proline glycine betaine binding ABC transporter protein ProX [KO:K05845 K05846]
F504_2095  Various polyols ABC transporter, ATP-binding component [KO:K10111] [EC:7.5.2.-]
F504_2100  Various polyols ABC transporter, periplasmic substrate-binding protein [KO:K10227]
F504_2098  Various polyols ABC transporter, permease component 1 [KO:K10228]
F504_2097  Various polyols ABC transporter, permease component 2 [KO:K10229]
F504_2924  yrbC; putative ABC transporter, auxiliary component YrbC [KO:K07323]
F504_336  ABC-type transport system involved in resistance to organic solvents, periplasmic component [KO:K02067]
F504_2927  yrbD; putative ABC transporter, periplasmic component YrbD [KO:K02067]
F504_334  ABC-type transport system involved in resistance to organic solvents, permease component USSDB6A [KO:K02066]
F504_2928  yrbE; putative ABC transporter, permease component YrbE [KO:K02066]
F504_2923  Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) [KO:K07122]
F504_335  Methionine ABC transporter ATP-binding protein [KO:K02065]
F504_2929  yrbF; putative ABC transporter, ATP-binding protein YrbF [KO:K02065]
F504_2133  Bmp family protein [KO:K07335]
F504_2131  small molecule transporter [KO:K23535]
F504_2132  Putative deoxyribose-specific ABC transporter, permease protein [KO:K23536]
F504_2130  Sugar ABC transporter, ATP-binding protein [KO:K23537]
F504_4173  hypothetical protein [KO:K10439]
F504_982  rbsB; Ribose ABC transport system, periplasmic ribose-binding protein RbsB [KO:K10439]
F504_980  rbsC; Ribose ABC transport system, permease protein RbsC [KO:K10440]
F504_981  rbsA; Ribose ABC transport system, ATP-binding protein RbsA [KO:K10441] [EC:7.5.2.7]
F504_2684  L-arabinose-binding periplasmic protein precursor AraF [KO:K10537]
F504_2682  L-arabinose transport system permease protein [KO:K10538]
F504_2683  araG; L-arabinose transport ATP-binding protein AraG [KO:K10539] [EC:7.5.2.12]
F504_5107  xylF; Xylose ABC transporter, periplasmic xylose-binding protein XylF [KO:K10543]
F504_5109  rbsC; Ribose ABC transport system, permease protein RbsC [KO:K10544]
F504_5108  xylG; D-xylose transport ATP-binding protein XylG [KO:K10545] [EC:7.5.2.10]
F504_1269  Inositol transport system sugar-binding protein [KO:K17213]
F504_1271  Inositol transport system permease protein [KO:K17214]
F504_1270  Inositol transport system ATP-binding protein [KO:K17215]
F504_3021  ugpA; Glycerol-3-phosphate ABC transporter, permease protein UgpA [KO:K17321]
F504_3018  ugpA; Glycerol-3-phosphate ABC transporter, permease protein UgpA [KO:K17322]
F504_3019  ugpE; Glycerol-3-phosphate ABC transporter, permease protein UgpE [KO:K17323]
F504_3016  ugpC; Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC [KO:K17324]
F504_3017  ugpC; Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC [KO:K17325]
F504_1293  Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein [KO:K05813]
F504_1294  ugpA; Glycerol-3-phosphate ABC transporter, permease protein UgpA [KO:K05814]
F504_1295  ugpE; Glycerol-3-phosphate ABC transporter, permease protein UgpE [KO:K05815]
F504_1296  ugpC; Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC [KO:K05816] [EC:7.6.2.10]
F504_1834  pstS; Phosphate ABC transporter, periplasmic phosphate-binding protein PstS [KO:K02040]
F504_3357  pstS; Phosphate ABC transporter, periplasmic phosphate-binding protein PstS [KO:K02040]
F504_1833  pstC; Phosphate transport system permease protein PstC [KO:K02037]
F504_1832  pstA; Phosphate transport system permease protein PstA [KO:K02038]
F504_1831  pstB; Phosphate transport ATP-binding protein PstB [KO:K02036] [EC:7.3.2.1]
F504_509  gltI; Glutamate Aspartate periplasmic binding protein precursor GltI [KO:K10001]
F504_93  Glutamate Aspartate periplasmic binding protein precursor GltI [KO:K10001]
F504_2222  gltI; Glutamate Aspartate periplasmic binding protein precursor GltI [KO:K10001]
F504_511  gltK; Glutamate Aspartate transport system permease protein GltK [KO:K10002]
F504_510  gltJ; Glutamate Aspartate transport system permease protein GltJ [KO:K10003]
F504_512  gltL; Glutamate Aspartate transport ATP-binding protein GltL [KO:K10004] [EC:7.4.2.1]
F504_2023  Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999]
F504_5056  livK; High-affinity leucine-specific transport system, periplasmic binding protein LivK [KO:K01999]
F504_2387  Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999]
F504_2400  Branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999]
F504_3347  Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999]
F504_3377  Extracellular ligand-binding receptor [KO:K01999]
F504_4796  hypothetical protein [KO:K01999]
F504_1639  Branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999]
F504_3503  Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999]
F504_2205  ABC transporter substrate-binding protein [KO:K01999]
F504_3390  Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999]
F504_4513  livH; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997]
F504_2399  livH; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997]
F504_4797  livH; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997]
F504_1638  livH; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997]
F504_3504  livH; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997]
F504_2209  livH; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997]
F504_3389  livH; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997]
F504_4512  livG; Branched-chain amino acid transport ATP-binding protein LivG [KO:K01995 K01998]
F504_3505  livM; Branched-chain amino acid transport system permease protein LivM [KO:K01998]
F504_2208  livM; Branched-chain amino acid transport system permease protein LivM [KO:K01998]
F504_1637  livM; Branched-chain amino acid transport system permease protein LivM [KO:K01998]
F504_4798  livM; Branched-chain amino acid transport system permease protein LivM [KO:K01998]
F504_3388  livM; Branched-chain amino acid transport system permease protein LivM [KO:K01998]
F504_2398  livM; Branched-chain amino acid transport system permease protein LivM [KO:K01998]
F504_2397  livG; Branched-chain amino acid transport ATP-binding protein LivG [KO:K01995]
F504_4799  livG; Branched-chain amino acid transport ATP-binding protein LivG [KO:K01995]
F504_1636  livG; Branched-chain amino acid transport ATP-binding protein LivG [KO:K01995]
F504_3506  livG; Branched-chain amino acid transport ATP-binding protein LivG [KO:K01995]
F504_2207  small molecule transporter [KO:K01995]
F504_3392  urtD; Urea ABC transporter, ATPase protein UrtD [KO:K01995]
F504_3507  livF; Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996]
F504_2206  livF; Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996]
F504_1635  livF; Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996]
F504_4800  livF; Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996]
F504_3391  livF; Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996]
F504_4511  livF; Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996]
F504_2396  livF; Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996]
F504_3436  Methionine ABC transporter substrate-binding protein [KO:K02073]
F504_901  Methionine ABC transporter substrate-binding protein [KO:K02073]
F504_900  Methionine ABC transporter permease protein [KO:K02072]
F504_899  Methionine ABC transporter ATP-binding protein [KO:K02071]
F504_1994  putative signal protein [KO:K11959]
F504_1993  ureB; Urea ABC transporter, permease protein UrtB [KO:K11960]
F504_1992  ureC; Urea ABC transporter, permease protein UrtC [KO:K11961]
F504_1991  ureD; Urea ABC transporter, ATPase protein UrtD [KO:K11962]
F504_1990  ureE; Urea ABC transporter, ATPase protein UrtE [KO:K11963]
F504_1423  Dipeptide-binding ABC transporter; Putative hemin-binding lipoprotein [KO:K13889]
F504_1424  dppB; Dipeptide transport system permease protein DppB [KO:K13890]
F504_1425  dppC; Dipeptide transport system permease protein DppC [KO:K13891]
F504_1422  dppD; Dipeptide transport ATP-binding protein DppD [KO:K13892]
F504_1200  ABC transporter, periplasmic substrate-binding protein [KO:K13893]
F504_1201  oppB; Oligopeptide transport system permease protein OppB [KO:K13894]
F504_1202  oppC; Oligopeptide transport system permease protein OppC [KO:K13895]
F504_1203  oppB; Oligopeptide transport system permease protein OppB [KO:K13896]
F504_1922  ABC-type multidrug transport system, permease component [KO:K09694]
F504_1921  nodI; Nodulation ABC transporter NodI [KO:K09695]
F504_1142  lolC; Lipoprotein releasing system transmembrane protein LolC [KO:K09808]
F504_1143  lolD; Lipoprotein releasing system ATP-binding protein LolD [KO:K09810] [EC:7.6.2.-]
F504_2374  putative permease [KO:K07091]
F504_2375  putative Permease [KO:K11720]
F504_431  lptB; Lipopolysaccharide ABC transporter, ATP-binding protein LptB [KO:K06861] [EC:7.5.2.5]
F504_4828  nosY; Nitrous oxide reductase maturation transmembrane protein NosY [KO:K19341]
F504_4827  nosF; Nitrous oxide reductase maturation protein NosF (ATPase) [KO:K19340]
F504_1581  ABC transporter, ATP-binding/permease protein [KO:K14698] [EC:7.-.-.-]
F504_1580  hypothetical protein [KO:K14699] [EC:7.-.-.-]
F504_2158  msbA; Lipid A export ATP-binding/permease protein MsbA [KO:K11085] [EC:7.5.2.6]
F504_3735  cyclolysin secretion ATP-binding protein [KO:K11004]
F504_506  msbA; Lipid A export ATP-binding/permease protein MsbA [KO:K24821]
F504_4678  ABC transporter, transmembrane region:ABC transporter:Peptidase C39, bacteriocin processing [KO:K12541]
F504_482  ABC transporter, fused ATPase and inner membrane subunits [KO:K02471]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
PMID:18424520
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
PMID:18375759
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
PMID:10557362
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
PMID:11731493
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
PMID:16135226
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
PMID:11929526
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
PMID:18326572
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
PMID:16109926
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
PMID:17873039
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
PMID:17214741
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
PMID:18805970
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
LinkDB

DBGET integrated database retrieval system