Entry Name ABC transporters - Streptococcus acidominimus
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Streptococcus acidominimus [GN:
saco ]
Gene SAME_01380 potD; spermidine/putrescine extracellular binding protein [KO:K11069 ]
SAME_00869 yehW_2; Osmotically activated L-carnitine/choline ABC transporter, permease protein OpuCD [KO:K05846 ]
SAME_00866 proV_1; Osmotically activated L-carnitine/choline ABC transporter, ATP-binding protein OpuCA [KO:K05847 ] [EC:7.6.2.9 ]
SAME_02133 msmK; Multiple sugar-binding transport ATP-binding protein msmK [KO:K10112 ] [EC:7.5.2.-]
SAME_01109 ycjP; putative maltose/maltodextrin ABC transporter, MalG permease [KO:K15772 ]
SAME_01168 pstS; putative phosphate ABC transporter, extracellular phosphate-binding lipoprotein [KO:K02040 ]
SAME_01757 peb1A; putative glutamine transport system substrate-binding protein [KO:K10039 ]
SAME_01758 artQ_2; putative glutamine transport system permease protein [KO:K10040 ]
SAME_01759 yecS_2; polar amino acid transport system permease protein [KO:K10040 ]
SAME_00241 tcyA; ABC-type amino acid transport/periplasmic component/domain protein [KO:K02424 ]
SAME_00465 yxeM; amino acid ABC transporter substrate-binding protein [KO:K02424 ]
SAME_01117 artP_2; polar amino acid transport system substrate-binding protein [KO:K23059 ]
SAME_01817 artQ_3; polar amino acid transport system permease protein [KO:K17077 ]
SAME_00589 livK; branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999 ]
SAME_00590 livH_1; branched chain amino acid ABC transporter permease [KO:K01997 ]
SAME_00591 livH_2; branched-chain amino acid ABC transporter permease [KO:K01998 ]
SAME_00592 lptB; branched-chain amino acid transport ATP-binding protein [KO:K01995 ]
SAME_00474 metQ_1; D-methionine transport system substrate-binding protein [KO:K02073 ]
SAME_00374 oppA_1; oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580 ]
SAME_00382 gsiA_2; peptide/nickel transport system ATP-binding protein [KO:K15583 ]
SAME_01855 troA; high-affinity zinc uptake system protein znuA precursor [KO:K11707 ]
SAME_02466 cbiO; cobalt transporter ATP-binding subunit [KO:K16786 ] [EC:7.-.-.-]
SAME_02465 cbiO3; cobalt/nickel transport system ATP-binding protein [KO:K16787 ] [EC:7.-.-.-]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
