KEGG   PATHWAY: sajs02010
Entry
sajs02010                   Pathway                                
Name
ABC transporters - Salinicola sp. JS01
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
sajs02010  ABC transporters
sajs02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Salinicola sp. JS01 [GN:sajs]
Gene
QO259_06900  cysP; thiosulfate ABC transporter substrate-binding protein CysP [KO:K02048]
QO259_06895  cysT; sulfate/thiosulfate ABC transporter permease CysT [KO:K02046]
QO259_06890  cysW; sulfate ABC transporter permease subunit CysW [KO:K02047]
QO259_06885  TOBE-like domain-containing protein [KO:K02045] [EC:7.3.2.3]
QO259_08745  ABC transporter substrate-binding protein [KO:K15598]
QO259_08740  ABC transporter permease [KO:K15599]
QO259_08735  ABC transporter ATP-binding protein [KO:K15600]
QO259_07890  modA; molybdate ABC transporter substrate-binding protein [KO:K02020]
QO259_07885  modB; molybdate ABC transporter permease subunit [KO:K02018]
QO259_07880  modC; molybdenum ABC transporter ATP-binding protein [KO:K02017] [EC:7.3.2.5]
QO259_01910  ABC transporter substrate-binding protein [KO:K02012]
QO259_06510  extracellular solute-binding protein [KO:K02012]
QO259_07165  spermidine/putrescine ABC transporter substrate-binding protein [KO:K11069]
QO259_07175  spermidine/putrescine ABC transporter substrate-binding protein [KO:K11069]
QO259_07180  ABC transporter permease [KO:K11070]
QO259_07185  ABC transporter permease [KO:K11071]
QO259_07190  ABC transporter ATP-binding protein [KO:K11072] [EC:7.6.2.11]
QO259_15280  ABC transporter substrate-binding protein [KO:K02002]
QO259_16745  glycine betaine ABC transporter substrate-binding protein [KO:K02002]
QO259_04180  ABC transporter substrate-binding protein [KO:K02002]
QO259_08615  glycine betaine ABC transporter substrate-binding protein [KO:K02002]
QO259_10205  choline ABC transporter substrate-binding protein [KO:K02002]
QO259_08620  proline/glycine betaine ABC transporter permease [KO:K02001]
QO259_08625  glycine betaine/L-proline ABC transporter ATP-binding protein [KO:K02000] [EC:7.6.2.9]
QO259_01655  ABC transporter substrate-binding protein [KO:K05845]
QO259_01640  ABC transporter permease [KO:K05846]
QO259_01650  ABC transporter permease [KO:K05846]
QO259_01645  ABC transporter ATP-binding protein [KO:K05847] [EC:7.6.2.9]
QO259_13100  ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10111] [EC:7.5.2.-]
QO259_02830  ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10111] [EC:7.5.2.-]
QO259_13115  sugar ABC transporter substrate-binding protein [KO:K10227]
QO259_13110  sugar ABC transporter permease [KO:K10228]
QO259_13105  carbohydrate ABC transporter permease [KO:K10229]
QO259_02825  ABC transporter substrate-binding protein [KO:K10236]
QO259_02845  ABC transporter substrate-binding protein [KO:K10236]
QO259_02840  sugar ABC transporter permease [KO:K10237]
QO259_02835  carbohydrate ABC transporter permease [KO:K10238]
QO259_06130  ABC transporter substrate-binding protein [KO:K07323]
QO259_06125  mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067]
QO259_06120  mlaE; lipid asymmetry maintenance ABC transporter permease subunit MlaE [KO:K02066]
QO259_06115  ATP-binding cassette domain-containing protein [KO:K02065]
QO259_14565  ABC transporter substrate-binding protein [KO:K10439]
QO259_14575  ABC transporter permease [KO:K10440]
QO259_14580  ABC transporter permease [KO:K10440]
QO259_14570  sugar ABC transporter ATP-binding protein [KO:K10441] [EC:7.5.2.7]
QO259_09590  arabinose ABC transporter substrate-binding protein [KO:K10537]
QO259_09580  araH; L-arabinose ABC transporter permease AraH [KO:K10538]
QO259_09585  araG; L-arabinose ABC transporter ATP-binding protein AraG [KO:K10539] [EC:7.5.2.12]
QO259_19390  ABC transporter substrate-binding protein [KO:K23508]
QO259_19375  yjfF; sugar ABC transporter permease YjfF [KO:K23509]
QO259_19380  ABC transporter permease [KO:K23509]
QO259_19385  sugar ABC transporter ATP-binding protein [KO:K10820] [EC:7.5.2.9]
QO259_13195  sugar ABC transporter substrate-binding protein [KO:K10552]
QO259_13200  ABC transporter permease [KO:K10553]
QO259_13205  ATP-binding cassette domain-containing protein [KO:K10554]
QO259_02070  D-ribose ABC transporter substrate-binding protein [KO:K17202]
QO259_02065  ABC transporter permease [KO:K17203]
QO259_02060  sugar ABC transporter ATP-binding protein [KO:K17204]
QO259_09495  ABC transporter substrate-binding protein [KO:K17321]
QO259_09510  sugar ABC transporter permease [KO:K17322]
QO259_09505  carbohydrate ABC transporter permease [KO:K17323]
QO259_09520  ABC transporter ATP-binding protein [KO:K17324]
QO259_09515  ABC transporter ATP-binding protein [KO:K17325]
QO259_16700  ugpB; sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB [KO:K05813]
QO259_16705  ugpA; sn-glycerol-3-phosphate ABC transporter permease UgpA [KO:K05814]
QO259_16710  ugpE; sn-glycerol-3-phosphate ABC transporter permease UgpE [KO:K05815]
QO259_16715  ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K05816] [EC:7.6.2.10]
QO259_06630  pstS; phosphate ABC transporter substrate-binding protein PstS [KO:K02040]
QO259_06635  pstC; phosphate ABC transporter permease subunit PstC [KO:K02037]
QO259_06640  pstA; phosphate ABC transporter permease PstA [KO:K02038]
QO259_06645  pstB; phosphate ABC transporter ATP-binding protein PstB [KO:K02036] [EC:7.3.2.1]
QO259_03180  putative selenate ABC transporter substrate-binding protein [KO:K02044]
QO259_03170  ABC transporter permease [KO:K02042]
QO259_03175  ATP-binding cassette domain-containing protein [KO:K02041] [EC:7.3.2.2]
QO259_15340  ABC transporter permease [KO:K10016]
QO259_18845  transporter substrate-binding domain-containing protein [KO:K10036]
QO259_18840  amino acid ABC transporter permease [KO:K10037]
QO259_19560  amino acid ABC transporter substrate-binding protein [KO:K09969]
QO259_19565  amino acid ABC transporter permease [KO:K09970]
QO259_19570  amino acid ABC transporter permease [KO:K09971]
QO259_19575  amino acid ABC transporter ATP-binding protein [KO:K09972] [EC:7.4.2.1]
QO259_05460  amino acid ABC transporter substrate-binding protein [KO:K16961]
QO259_05455  amino acid ABC transporter permease [KO:K16962]
QO259_05450  amino acid ABC transporter ATP-binding protein [KO:K16963]
QO259_15350  transporter substrate-binding domain-containing protein [KO:K10022]
QO259_15360  ABC transporter substrate-binding protein [KO:K10022]
QO259_13475  transporter substrate-binding domain-containing protein [KO:K10022]
QO259_15345  ABC transporter permease [KO:K10023]
QO259_15335  ATP-binding cassette domain-containing protein [KO:K10025] [EC:7.4.2.1]
QO259_15105  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
QO259_15865  ABC transporter substrate-binding protein [KO:K01999]
QO259_15100  branched-chain amino acid ABC transporter permease [KO:K01997]
QO259_15855  branched-chain amino acid ABC transporter permease [KO:K01997]
QO259_15095  branched-chain amino acid ABC transporter permease [KO:K01998]
QO259_15860  branched-chain amino acid ABC transporter permease [KO:K01998]
QO259_15090  ABC transporter ATP-binding protein [KO:K01995]
QO259_15845  ABC transporter ATP-binding protein [KO:K01995]
QO259_15085  ABC transporter ATP-binding protein [KO:K01996]
QO259_15850  ABC transporter ATP-binding protein [KO:K01996]
QO259_09480  MetQ/NlpA family ABC transporter substrate-binding protein [KO:K02073]
QO259_09475  methionine ABC transporter permease [KO:K02072]
QO259_09470  methionine ABC transporter ATP-binding protein [KO:K02071]
QO259_05370  urtA; urea ABC transporter substrate-binding protein [KO:K11959]
QO259_05375  urtB; urea ABC transporter permease subunit UrtB [KO:K11960]
QO259_05380  urtC; urea ABC transporter permease subunit UrtC [KO:K11961]
QO259_05385  urtD; urea ABC transporter ATP-binding protein UrtD [KO:K11962]
QO259_05390  urtE; urea ABC transporter ATP-binding subunit UrtE [KO:K11963]
QO259_14810  peptide ABC transporter substrate-binding protein [KO:K15580]
QO259_14825  peptide ABC transporter substrate-binding protein [KO:K15580]
QO259_14835  peptide ABC transporter substrate-binding protein [KO:K15580]
QO259_14840  peptide ABC transporter substrate-binding protein [KO:K15580]
QO259_14845  oppB; oligopeptide ABC transporter permease OppB [KO:K15581]
QO259_14850  ABC transporter permease subunit [KO:K15582]
QO259_08825  dipeptide ABC transporter ATP-binding protein [KO:K10823 K15583]
QO259_14855  ABC transporter ATP-binding protein [KO:K10823 K15583]
QO259_16740  ABC transporter substrate-binding protein [KO:K12368]
QO259_16735  ABC transporter permease subunit [KO:K12369]
QO259_16730  ABC transporter permease subunit [KO:K12370]
QO259_16725  ATP-binding cassette domain-containing protein [KO:K12371]
QO259_16720  dipeptide ABC transporter ATP-binding protein [KO:K12372]
QO259_08810  extracellular solute-binding protein [KO:K13893]
QO259_08815  yejB; microcin C ABC transporter permease YejB [KO:K13894]
QO259_08820  ABC transporter permease [KO:K13895]
QO259_15055  ABC transporter substrate-binding protein [KO:K25286]
QO259_15040  ABC transporter ATP-binding protein [KO:K23188] [EC:7.2.2.17 7.2.2.-]
QO259_04780  ABC transporter substrate-binding protein [KO:K23227]
QO259_04775  fhuB; Fe(3+)-hydroxamate ABC transporter permease FhuB [KO:K23228]
QO259_04335  ATP-binding cassette domain-containing protein [KO:K10829] [EC:7.2.2.16]
QO259_16140  metal ABC transporter substrate-binding protein [KO:K11604]
QO259_16150  metal ABC transporter permease [KO:K11605]
QO259_16155  metal ABC transporter permease [KO:K11606]
QO259_16145  manganese/iron ABC transporter ATP-binding protein [KO:K11607]
QO259_03780  ABC transporter permease [KO:K09690]
QO259_03785  ABC transporter ATP-binding protein [KO:K09691] [EC:7.5.2.14]
QO259_07415  lipoprotein-releasing ABC transporter permease subunit [KO:K09808]
QO259_12755  lptF; LPS export ABC transporter permease LptF [KO:K07091]
QO259_12750  lptG; LPS export ABC transporter permease LptG [KO:K11720]
QO259_06095  lptB; LPS export ABC transporter ATP-binding protein [KO:K06861] [EC:7.5.2.5]
QO259_14745  ftsX; permease-like cell division protein FtsX [KO:K09811]
QO259_14750  ftsE; cell division ATP-binding protein FtsE [KO:K09812]
QO259_07435  msbA; lipid A export permease/ATP-binding protein MsbA [KO:K11085] [EC:7.5.2.6]
QO259_19525  ABC transporter ATP-binding protein [KO:K18893]
QO259_03485  type I secretion system permease/ATPase [KO:K12541]
QO259_12005  type I secretion system permease/ATPase [KO:K12541]
QO259_03755  type I secretion system permease/ATPase [KO:K12536]
QO259_09070  cydC; thiol reductant ABC exporter subunit CydC [KO:K16012]
QO259_09075  cydD; thiol reductant ABC exporter subunit CydD [KO:K16013]
QO259_04275  multidrug ABC transporter permease/ATP-binding protein [KO:K06159]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
PMID:18424520
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
PMID:18375759
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
PMID:10557362
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
PMID:11731493
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
PMID:16135226
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
PMID:11929526
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
PMID:18326572
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
PMID:16109926
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
PMID:17873039
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
PMID:17214741
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
PMID:18805970
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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