KEGG   PATHWAY: sgc00740
Entry
sgc00740                    Pathway                                
Name
Riboflavin metabolism - Streptococcus agalactiae GD201008-001 (serotype Ia)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
sgc00740  Riboflavin metabolism
sgc00740

Module
sgc_M00125  Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:sgc00740]
Other DBs
GO: 0006771
Organism
Streptococcus agalactiae GD201008-001 (serotype Ia) [GN:sgc]
Gene
A964_0751  ribBA; Riboflavin biosynthesis protein ribBA [KO:K14652] [EC:4.1.99.12 3.5.4.25]
A964_0749  ribD; riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
A964_0368  cof family hydrolase [KO:K21064] [EC:3.1.3.104]
A964_0752  ribH; 6,7-dimethyl-8-ribityllumazine synthase [KO:K00794] [EC:2.5.1.78]
A964_0750  ribE; riboflavin synthase subunit alpha [KO:K00793] [EC:2.5.1.9]
A964_0976  ribF; macrolide-efflux protein [KO:K11753] [EC:2.7.1.26 2.7.7.2]
A964_0844  thiM; hydroxyethylthiazole kinase [KO:K00878] [EC:2.7.1.50]
A964_1444  nudF; MutT/nudix family protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
sgc00030  Pentose phosphate pathway
sgc00040  Pentose and glucuronate interconversions
sgc00230  Purine metabolism
sgc00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   
LinkDB

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