Entry Name ABC transporters - Streptococcus pneumoniae 670-6B (serotype 6B)
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Streptococcus pneumoniae 670-6B (serotype 6B) [GN:
snb ]
Gene SP670_0313 ABC transporter membrane-spanning permease - iron transport [KO:K02011 ]
SP670_1898 binding-protein-dependent transport systems inner membrane component [KO:K02011 ]
SP670_2011 binding-protein-dependent transport systems inner membrane component [KO:K02011 ]
SP670_0314 ABC transporter membrane-spanning permease - iron transport [KO:K02011 ]
SP670_0911 spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein [KO:K11069 ]
SP670_0910 ABC transporter membrane-spanning permease - spermidine/putrescine transport [KO:K11070 ]
SP670_0909 ABC transporter membrane-spanning permease - spermidine/putrescine transport [KO:K11071 ]
SP670_1665 multiple sugar-binding transport ATP-binding protein MsmK [KO:K10112 ] [EC:7.5.2.-]
SP670_2250 ABC transporter membrane-spanning permease - maltose/maltodextrin [KO:K15772 ]
SP670_1479 ABC transporter membrane-spanning permease - ribose/galactose transport [KO:K23535 ]
SP670_1478 ABC transporter membrane-spanning permease - ribose/galactose transport [KO:K23536 ]
SP670_2224 ABC transporter substrate-binding protein - phosphate transport [KO:K02040 ]
SP670_0668 ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor [KO:K10039 ]
SP670_0666 ABC transporter membrane-spanning permease - glutamine transport [KO:K10040 ]
SP670_0667 ABC transporter membrane-spanning permease - glutamine transport [KO:K10040 ]
SP670_0228 ABC transporter substrate-binding protein - amino acid transport [KO:K02424 ]
SP670_0835 ABC transporter membrane-spanning permease - aspartate/glutamate transport [KO:K10009 ]
SP670_0903 ABC transporter substrate-binding protein - glutamine-binding protein [KO:K23059 ]
SP670_1575 ABC transporter substrate-binding protein - branched chain amino acid transport [KO:K01999 ]
SP670_1573 ABC transporter membrane-spanning permease - branched chain amino acid transport [KO:K01998 ]
SP670_1291 ABC transporter substrate-binding protein - iron transport [KO:K25286 ]
SP670_1289 ABC transporter membrane-spanning permease - iron transport [KO:K23187 ]
SP670_1408 ABC-type antimicrobial peptide transport system, permease component [KO:K19084 ]
SP670_0864 ABC transporter, ATP-binding/permease protein [KO:K14698 ] [EC:7.-.-.-]
SP670_0120 transport/processing ATP-binding protein ComA [KO:K12292 ] [EC:3.4.22.-]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
