KEGG   PATHWAY: ssh00740
Entry
ssh00740                    Pathway                                
Name
Riboflavin metabolism - Staphylococcus schweitzeri
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
ssh00740  Riboflavin metabolism
ssh00740

Module
ssh_M00125  Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:ssh00740]
Other DBs
GO: 0006771
Organism
Staphylococcus schweitzeri [GN:ssh]
Gene
NCTC13712_01759  ribBA; Riboflavin biosynthesis protein ribBA [KO:K14652] [EC:4.1.99.12 3.5.4.25]
NCTC13712_01761  ribD; Riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
NCTC13712_00916  yidA_1; Phosphatase YidA [KO:K21064] [EC:3.1.3.104]
NCTC13712_01758  ribH; 6,7-dimethyl-8-ribityllumazine synthase [KO:K00794] [EC:2.5.1.78]
NCTC13712_01760  ribE; Riboflavin synthase alpha chain [KO:K00793] [EC:2.5.1.9]
NCTC13712_01217  ribF; Riboflavin biosynthesis protein ribF [KO:K11753] [EC:2.7.1.26 2.7.7.2]
NCTC13712_00286  ssuE; FMN reductase (NADPH) [KO:K00299] [EC:1.5.1.38]
NCTC13712_00326  nfrA; NADPH-dependent oxidoreductase [KO:K19285] [EC:1.5.1.38]
NCTC13712_02033  thiM; Hydroxyethylthiazole kinase [KO:K00878] [EC:2.7.1.50]
NCTC13712_01491  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
ssh00030  Pentose phosphate pathway
ssh00040  Pentose and glucuronate interconversions
ssh00230  Purine metabolism
ssh00860  Porphyrin metabolism
ssh00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   
LinkDB

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