KEGG   PATHWAY: ssp02010
Entry
ssp02010                    Pathway                                
Name
ABC transporters - Staphylococcus saprophyticus
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
ssp02010  ABC transporters
ssp02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Staphylococcus saprophyticus [GN:ssp]
Gene
SSP0632  ABC-type molybdate transport system periplasmic component [KO:K02020]
SSP0633  putative ABC-type sulfate molybdate transport system permease component [KO:K02018]
SSP0634  putative ABC-type sulfate molybdate transport system ATPase component [KO:K02017] [EC:7.3.2.5]
SSP1687  spermidine putrescine-binding periplasmic protein [KO:K11069]
SSP1688  ABC-type spermidine putrescine transport system permease component II [KO:K11070]
SSP1689  ABC-type spermidine putrescine transport system permease component I [KO:K11071]
SSP1690  ABC-type spermidine putrescine transport system ATPase component [KO:K11072] [EC:7.6.2.11]
SSPP223  putative periplasmic component of ABC-type proline glycine betaine transport system [KO:K02002]
SSP1996  putative periplasmic glycine betaine choline-binding protein of an ABC-type transport system [KO:K05845 K05846]
SSP0993  periplasmic glycine betaine choline-binding protein of an ABC-type transport system osmoprotectant binding protein [KO:K05845]
SSP0453  periplasmic glycine betaine choline-binding protein of an ABC-type transport system [KO:K05845]
SSP0452  ABC-type proline glycine betaine transport system permease component [KO:K05846]
SSP0454  ABC-type proline glycine betaine transport system permease component [KO:K05846]
SSP1997  putative ABC-type proline glycine betaine transport system ATPase component [KO:K05847] [EC:7.6.2.9]
SSP0451  ABC-type proline glycine betaine transport system ATPase component [KO:K05847] [EC:7.6.2.9]
SSP1392  ribose ABC transporter [KO:K10439]
SSP1393  ribose ABC transporter [KO:K10440]
SSP1394  ribose transport ATP-binding protein rbsA [KO:K10441] [EC:7.5.2.7]
SSP1395  High affinity ribose transport protein rbsD [KO:K06726] [EC:5.4.99.62]
SSP1361  ABC-type phosphate transport system periplasmic component [KO:K02040]
SSP1362  ABC-type phosphate transport system permease component [KO:K02037]
SSP1363  ABC-type phosphate transport system permease component [KO:K02038]
SSP1364  ABC-type phosphate transport system ATPase component [KO:K02036] [EC:7.3.2.1]
SSP1427  putative phosphate phosphonate-binding protein [KO:K02044]
SSP1424  ABC-type phosphate phosphonate transport system permease component [KO:K02042]
SSP1425  ABC-type phosphate phosphonate transport system permease component [KO:K02042]
SSP1426  ABC-type phosphate phosphonate transport system ATPase component [KO:K02041] [EC:7.3.2.2]
SSP0242  ABC-type amino acid transport system periplasmic component [KO:K02424]
SSP0243  ABC-type amino acid transport system permease component [KO:K10009]
SSP0244  ABC-type polar amino acid transport system ATPase component [KO:K10010] [EC:7.4.2.1]
SSP0620  putative ABC-type amino acid transport system periplasmic component [KO:K16957]
SSP0619  putative ABC-type amino acid transport system permease component [KO:K16958]
SSP0618  ABC-type amino acid transport system permease component [KO:K16959]
SSP0621  putative ABC-type polar amino acid transport system ATPase component [KO:K16960] [EC:7.4.2.1]
SSP0937  truncated ABC-type amino acid transport system periplasmic component [KO:K17077 K23059]
SSP0938  ABC-type polar amino acid transport system ATPase component [KO:K23060] [EC:7.4.2.1]
SSP1864  ABC-type uncharacterized transport system periplasmic component [KO:K02073]
SSP0248  ABC-type uncharacterized transport system periplasmic component [KO:K02073]
SSP1865  putative ABC transporter permease component [KO:K02072]
SSP1866  Uncharacterized ABC-type transport system ATPase component [KO:K02071]
SSP1790  ABC-type dipeptide oligopeptide nickel transport system periplasmic component [KO:K15580]
SSP1794  ABC-type dipeptide oligopeptide nickel transport system permease component [KO:K15581]
SSP1793  ABC-type dipeptide oligopeptide nickel transport system permease component [KO:K15582]
SSP1792  ABC-type dipeptide oligopeptide nickel transport system ATPase component [KO:K15583]
SSP1791  ABC-type dipeptide oligopeptide nickel transport system ATPase component [KO:K10823]
SSP0709  putative ABC-type cobalamin Fe3+-siderophores transport system periplasmic component [KO:K23181]
SSP0182  ferrichrome ABC transporter [KO:K23181]
SSP0711  putative ABC-type cobalamin Fe3+-siderophores transport system permease component [KO:K23182]
SSP0710  putative ABC-type cobalamin Fe3+-siderophores transport system permease component [KO:K23183]
SSP2088  putative ABC-type Mn Zn transport system periplasmic Mn Zn-binding protein [KO:K19975]
SSP2087  putative ABC-type Mn2+ Zn2+ transport system permease component [KO:K19976]
SSP2086  putative ABC-type Mn Zn transport system ATPase component [KO:K19973] [EC:7.2.2.5]
SSP0388  putative ABC-type Mn Zn transport system periplasmic Mn Zn-binding protein [KO:K09815]
SSP0490  putative ABC-type Mn Zn transport system periplasmic Mn Zn-binding protein [KO:K09815]
SSP1201  putative ABC transport system permease component [KO:K09816]
SSP1200  putative ABC transport system ATPase component [KO:K09817] [EC:7.2.2.20]
SSP0625  putative biotin biosynthesis protein [KO:K03523]
SSP0693  putative ABC-type cobalt transport system permease component [KO:K16785]
SSP1715  putative ABC-type cobalt transport system permease component [KO:K16785]
SSP0359  ABC-type cobalt transport system permease component [KO:K16785]
SSP0691  putative ABC transporter ATP-binding protein [KO:K16786] [EC:7.-.-.-]
SSP0692  putative ABC transporter ATP-binding protein [KO:K16787] [EC:7.-.-.-]
SSP0923  putative ABC-type polysaccharide polyol phosphate export system permease component [KO:K09692]
SSP2081  teichoic acid ABC transporter permease protein [KO:K09692]
SSP0950  teichoic acid translocation permease protein [KO:K09692]
SSP2195  putative teichoic acid translocation permease [KO:K09692]
SSP0922  putative ABC-type polysaccharide polyol phosphate transport system ATPase component [KO:K09693] [EC:7.5.2.4]
SSP2082  teichoic acid ABC transporter ATP-binding protein [KO:K09693] [EC:7.5.2.4]
SSP0542  ABC-type transport system involved in lipoprotein release permease component [KO:K09813]
SSP0543  ABC-type transport system involved in lipoprotein release ATPase component [KO:K09814] [EC:7.6.2.-]
SSP0300  ABC-type transport system involved in lipoprotein release permease component [KO:K11632]
SSP0299  ABC-type transport system involved in lipoprotein release ATPase component [KO:K11631]
SSP0385  ABC-type multidrug protein lipid transport system ATPase component [KO:K18889]
SSP0386  ABC-type multidrug protein lipid transport system ATPase component [KO:K18890]
SSP2076  ABC-type transport system ATPase component [KO:K18104] [EC:7.6.2.2]
SSP2033  putative ABC-type transport system ATPase component [KO:K16012]
SSP2034  putative ABC-type transport system ATPase component [KO:K16013]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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