KEGG   PATHWAY: ssw02010
Entry
ssw02010                    Pathway                                
Name
ABC transporters - Streptococcus suis GZ1 (serotype 2)
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
ssw02010  ABC transporters
ssw02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Streptococcus suis GZ1 (serotype 2) [GN:ssw]
Gene
SSGZ1_0200  NLPA lipoprotein [KO:K15553]
SSGZ1_0198  Binding-protein-dependent transport systems inner membrane component [KO:K15554]
SSGZ1_0199  taurine ABC transporter, ATP-binding protein [KO:K15555] [EC:7.6.2.14]
SSGZ1_0791  extracellular solute-binding protein, family 1 [KO:K11069]
SSGZ1_0790  Binding-protein-dependent transport systems inner membrane component protein [KO:K11070]
SSGZ1_0789  Binding-protein-dependent transport systems inner membrane component protein [KO:K11071]
SSGZ1_0788  spermidine/putrescine ABC transporter, ATP-binding protein [KO:K11072] [EC:7.6.2.11]
SSGZ1_1431  putative osmoprotectant-binding protein [KO:K05845 K05846]
SSGZ1_1432  putative ATP-binding protein opuCA [KO:K05847] [EC:7.6.2.9]
SSGZ1_1721  Sulfate-transporting ATPase [KO:K10112] [EC:7.5.2.-]
SSGZ1_1936  Maltose/maltodextrin-binding protein precursor [KO:K15770]
SSGZ1_1937  MalC [KO:K15771]
SSGZ1_1938  MalD [KO:K15772]
SSGZ1_1389  multiple sugar-binding ABC transporter, sugar-binding protein [KO:K10117]
SSGZ1_1388  Binding-protein-dependent transport systems inner membrane component [KO:K10118]
SSGZ1_1387  Binding-protein-dependent transport systems inner membrane component [KO:K10119]
SSGZ1_1727  ABC transporter, solute binding protein [KO:K17318]
SSGZ1_1729  ABC transporter membrane spanning permease - sugar transport [KO:K17319]
SSGZ1_1728  ABC transporter membrane spanning permease - sugar transport [KO:K17320]
SSGZ1_0954  Basic membrane lipoprotein [KO:K07335]
SSGZ1_0952  ABC transporter membrane-spanning permease - ribose/galactose transport [KO:K23535]
SSGZ1_0951  putative sugar ABC transporter, permease protein [KO:K23536]
SSGZ1_0953  putative Sugar ABC transporter, ATP-binding protein [KO:K23537]
SSGZ1_0970  extracellular solute-binding protein, family 1 [KO:K02040]
SSGZ1_0969  Binding-protein-dependent transport systems related protein [KO:K02037]
SSGZ1_0968  Binding-protein-dependent transport systems related protein [KO:K02038]
SSGZ1_0966  putative Phosphate import ATP-binding protein pstB 1 [KO:K02036] [EC:7.3.2.1]
SSGZ1_0967  ABC transporter ATP-binding protein - phosphate transport [KO:K02036] [EC:7.3.2.1]
SSGZ1_0906  Amino acid ABC transporter,3-TM region containing permease protein [KO:K10036 K10037]
SSGZ1_0908  Phosphate-transporting ATPase [KO:K10038] [EC:7.4.2.1]
SSGZ1_1209  Major cell-binding factor precursor (CBF1) [KO:K10039]
SSGZ1_1211  ABC transporter membrane-spanning permease - glutamine transport [KO:K10040]
SSGZ1_1210  ABC transporter membrane-spanning permease - glutamine transport [KO:K10040]
SSGZ1_1208  amino acid ABC transporter, ATP-binding protein [KO:K10041] [EC:7.4.2.1]
SSGZ1_1879  extracellular solute-binding protein [KO:K02424]
SSGZ1_0280  extracellular solute-binding protein, family 3 [KO:K02424]
SSGZ1_1878  Amino acid ABC transporter, permease protein [KO:K10009]
SSGZ1_0281  Amino acid ABC transporter, permease protein [KO:K10009]
SSGZ1_1877  putative amino acid ABC transporter, ATP-binding protein [KO:K10010] [EC:7.4.2.1]
SSGZ1_0899  extracellular solute-binding protein, family 3 [KO:K23059]
SSGZ1_0900  putative amino acid transporter [KO:K23059]
SSGZ1_0442  permease protein [KO:K17077]
SSGZ1_0443  putative amino acid ABC transporter, ATP-binding protein [KO:K23060] [EC:7.4.2.1]
SSGZ1_1695  amino acid ABC transporter, amino acid-binding protein/permease protein [KO:K17073 K17074]
SSGZ1_1696  Amino acid transport ATP-binding protein [KO:K17076]
SSGZ1_1381  ABC-type branched-chain amino acid transport systems, periplasmic component [KO:K01999]
SSGZ1_1380  branched-chain amino acid ABC transporter, permease protein [KO:K01997]
SSGZ1_1379  branched-chain amino acid ABC transporter, permease protein [KO:K01998]
SSGZ1_1378  branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
SSGZ1_1377  ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996]
SSGZ1_1595  putative permease: ABC transporter [KO:K02072]
SSGZ1_1596  Sulfate-transporting ATPase [KO:K02071]
SSGZ1_0108  zinc ABC transporter, zinc-binding lipoprotein [KO:K09815]
SSGZ1_0305  Periplasmic solute binding protein [KO:K09815]
SSGZ1_0107  adcB, ABC transporter membrane-spanning permease - Zinc (Zn2+) transport [KO:K09816]
SSGZ1_0106  adcC, ABC transporter ATP-binding domain - Zinc (Zn2+) permease [KO:K09817] [EC:7.2.2.20]
SSGZ1_1894  High-affinity zinc uptake system protein znuA precursor [KO:K11707]
SSGZ1_1892  Zinc transport system membrane protein troC [KO:K11708]
SSGZ1_1891  permease:zinc ABC transporter [KO:K11709]
SSGZ1_1893  ABC transporter related protein [KO:K11710] [EC:7.2.2.5]
SSGZ1_0458  biotin synthase (BioY family protein), putative [KO:K03523]
SSGZ1_0729  cobalt ABC transporter permease protein [KO:K16785]
SSGZ1_1969  Cobalt transport protein cbiO [KO:K16785]
SSGZ1_0363  Cobalt transport protein [KO:K16785]
SSGZ1_0262  ABC-type cobalt transport system, permease component CbiQ-like protein [KO:K16785]
SSGZ1_1971  Cobalt import ATP-binding protein cbiO 2 [KO:K16786] [EC:7.-.-.-]
SSGZ1_0730  cobalt ABC transporter ATP-binding protein [KO:K16786] [EC:7.-.-.-]
SSGZ1_0731  cobalt ABC transporter ATP-binding protein [KO:K16787] [EC:7.-.-.-]
SSGZ1_1970  putative Cobalt import ATP-binding protein cbiO 1 [KO:K16787] [EC:7.-.-.-]
SSGZ1_0859  putative bacteriocin operon protein ScnE [KO:K20460]
SSGZ1_0858  putative bacteroiocin operon protein ScnG [KO:K20461]
SSGZ1_0860  ABC transporter [KO:K20459]
SSGZ1_1424  putative permease protein [KO:K19084]
SSGZ1_0856  putative permease protein [KO:K19084]
SSGZ1_1425  putative ABC-type bacitracin resistance protein A [KO:K19083]
SSGZ1_0857  putative ABC transporter, ATP-binding protein [KO:K19083]
SSGZ1_1253  Cell division protein [KO:K09811]
SSGZ1_1254  Cell division ATP-binding protein [KO:K09812]
SSGZ1_0270  ABC transporter, permease protein [KO:K18889]
SSGZ1_0269  ABC transporter,transmembrane region [KO:K18890]
SSGZ1_0043  ABC transporter,ATP binding protein [KO:K18104] [EC:7.6.2.2]
SSGZ1_1849  putative ABC transporter, ATP-binding protein [KO:K18891]
SSGZ1_1848  ABC transporter, transmembrane region [KO:K18892]
SSGZ1_1249  Multidrug resistance-like ATP-binding protein [KO:K18216]
SSGZ1_1248  Putative ABC transporter, ATP-binding protein [KO:K18217]
SSGZ1_0782  putative ABC transporter, ATP-binding protein [KO:K18887]
SSGZ1_0933  ABC transporter related protein [KO:K18887]
SSGZ1_0783  ABC transporter, transmembrane region containing protein [KO:K18888]
SSGZ1_0932  ABC transporter related protein [KO:K18888]
SSGZ1_1203  Erythromycin resistance ATP-binding protein msrA [KO:K18231]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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