KEGG   PATHWAY: sue00740
Entry
sue00740                    Pathway                                
Name
Riboflavin metabolism - Staphylococcus aureus subsp. aureus ED133
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
sue00740  Riboflavin metabolism
sue00740

Module
sue_M00125  Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:sue00740]
Other DBs
GO: 0006771
Organism
Staphylococcus aureus subsp. aureus ED133 [GN:sue]
Gene
SAOV_1752  ribA; riboflavin biosynthesis protein [KO:K14652] [EC:4.1.99.12 3.5.4.25]
SAOV_1754  ribD; riboflavin specific deaminase [KO:K11752] [EC:3.5.4.26 1.1.1.193]
SAOV_0918c  probable hydrolase [KO:K21064] [EC:3.1.3.104]
SAOV_1751  ribH; 6,7-dimethyl-8-ribityllumazine synthase [KO:K00794] [EC:2.5.1.78]
SAOV_1753  ribE; riboflavin synthase alpha chain [KO:K00793] [EC:2.5.1.9]
SAOV_1274  ribC; bifunctional protein including riboflavin kinase and FAD synthase [KO:K11753] [EC:2.7.1.26 2.7.7.2]
SAOV_0364  FMN reductase-related protein [KO:K00299] [EC:1.5.1.38]
SAOV_0405  Nitroreductase family protein [KO:K19285] [EC:1.5.1.38]
SAOV_2133c  hydroxyethylthiazole kinase [KO:K00878] [EC:2.7.1.50]
SAOV_1501  probable ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
PMID:12136096
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
PMID:11856310
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
PMID:12867427
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
PMID:16042598
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
sue00030  Pentose phosphate pathway
sue00040  Pentose and glucuronate interconversions
sue00230  Purine metabolism
sue00860  Porphyrin metabolism
sue00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   
LinkDB

DBGET integrated database retrieval system