KEGG   PATHWAY: sws02010
Entry
sws02010                    Pathway                                
Name
ABC transporters - Sutterella wadsworthensis
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
sws02010  ABC transporters
sws02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Sutterella wadsworthensis [GN:sws]
Gene
I6J16_05305  cysP; thiosulfate ABC transporter substrate-binding protein CysP [KO:K02048]
I6J16_05300  cysT; sulfate/thiosulfate ABC transporter permease CysT [KO:K02046]
I6J16_05295  cysW; sulfate ABC transporter permease subunit CysW [KO:K02047]
I6J16_05290  cysA; sulfate ABC transporter ATP-binding protein [KO:K02045] [EC:7.3.2.3]
I6J16_01080  NrtA/SsuA/CpmA family ABC transporter substrate-binding protein [KO:K15553]
I6J16_01160  ABC transporter permease [KO:K15554]
I6J16_01165  ABC transporter ATP-binding protein [KO:K15555] [EC:7.6.2.14]
I6J16_06630  modA; molybdate ABC transporter substrate-binding protein [KO:K02020]
I6J16_06635  ABC transporter permease subunit [KO:K02018]
I6J16_11895  modB; molybdate ABC transporter permease subunit [KO:K02018]
I6J16_06625  ATP-binding cassette domain-containing protein [KO:K02017] [EC:7.3.2.5]
I6J16_11900  modC; molybdenum ABC transporter ATP-binding protein [KO:K02017] [EC:7.3.2.5]
I6J16_03390  ABC transporter substrate-binding protein [KO:K02012]
I6J16_01880  extracellular solute-binding protein [KO:K02012]
I6J16_02615  ABC transporter permease subunit [KO:K02011 K02012]
I6J16_02620  ABC transporter substrate-binding protein [KO:K02012]
I6J16_03395  iron ABC transporter permease [KO:K02011]
I6J16_01885  iron ABC transporter permease [KO:K02011]
I6J16_03400  ABC transporter ATP-binding protein [KO:K02010] [EC:7.2.2.7]
I6J16_01875  ABC transporter ATP-binding protein [KO:K02010] [EC:7.2.2.7]
I6J16_02610  ABC transporter ATP-binding protein [KO:K02010] [EC:7.2.2.7]
I6J16_06450  ABC transporter ATP-binding protein [KO:K10112] [EC:7.5.2.-]
I6J16_01745  ABC transporter ATP-binding protein [KO:K10112] [EC:7.5.2.-]
I6J16_09845  ABC transporter substrate-binding protein [KO:K07323]
I6J16_09855  mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067]
I6J16_09860  mlaE; lipid asymmetry maintenance ABC transporter permease subunit MlaE [KO:K02066]
I6J16_09840  STAS domain-containing protein [KO:K07122]
I6J16_09865  ABC transporter ATP-binding protein [KO:K02065]
I6J16_01830  BMP family ABC transporter substrate-binding protein [KO:K07335]
I6J16_01835  BMP family ABC transporter substrate-binding protein [KO:K07335]
I6J16_01845  ABC transporter permease [KO:K23535]
I6J16_01840  ABC transporter permease [KO:K23536]
I6J16_01850  ABC transporter ATP-binding protein [KO:K23537]
I6J16_00515  phosphate ABC transporter substrate-binding protein [KO:K02040]
I6J16_00520  pstC; phosphate ABC transporter permease subunit PstC [KO:K02037]
I6J16_00525  pstA; phosphate ABC transporter permease PstA [KO:K02038]
I6J16_00530  pstB; phosphate ABC transporter ATP-binding protein PstB [KO:K02036] [EC:7.3.2.1]
I6J16_04310  basic amino acid ABC transporter substrate-binding protein [KO:K10036]
I6J16_04315  basic amino acid ABC transporter substrate-binding protein [KO:K10036]
I6J16_04655  basic amino acid ABC transporter substrate-binding protein [KO:K10036]
I6J16_01120  basic amino acid ABC transporter substrate-binding protein [KO:K10036]
I6J16_02665  basic amino acid ABC transporter substrate-binding protein [KO:K10036]
I6J16_01115  amino acid ABC transporter permease [KO:K10037]
I6J16_11210  amino acid ABC transporter substrate-binding protein [KO:K10001]
I6J16_11200  ABC transporter permease subunit [KO:K10002]
I6J16_11205  amino acid ABC transporter permease [KO:K10003]
I6J16_11195  amino acid ABC transporter ATP-binding protein [KO:K10004] [EC:7.4.2.1]
I6J16_10765  amino acid ABC transporter substrate-binding protein [KO:K09969]
I6J16_10770  ABC transporter permease subunit [KO:K09970]
I6J16_10775  amino acid ABC transporter permease [KO:K09971]
I6J16_04620  amino acid ABC transporter substrate-binding protein [KO:K02424]
I6J16_07540  transporter substrate-binding domain-containing protein [KO:K02424]
I6J16_04625  amino acid ABC transporter permease [KO:K10009]
I6J16_04630  amino acid ABC transporter ATP-binding protein [KO:K10010] [EC:7.4.2.1]
I6J16_03990  MetQ/NlpA family ABC transporter substrate-binding protein [KO:K02073]
I6J16_05480  methionine ABC transporter substrate-binding protein [KO:K02073]
I6J16_05515  MetQ/NlpA family ABC transporter substrate-binding protein [KO:K02073]
I6J16_05690  MetQ/NlpA family ABC transporter substrate-binding protein [KO:K02073]
I6J16_06740  MetQ/NlpA family ABC transporter substrate-binding protein [KO:K02073]
I6J16_05500  ABC transporter permease subunit [KO:K02072]
I6J16_11615  ABC transporter permease [KO:K02072]
I6J16_05505  methionine ABC transporter ATP-binding protein [KO:K02071]
I6J16_11620  methionine ABC transporter ATP-binding protein [KO:K02071]
I6J16_04540  nikA; nickel ABC transporter, nickel/metallophore periplasmic binding protein [KO:K15584]
I6J16_04545  ABC transporter permease subunit [KO:K15585]
I6J16_04550  ABC transporter permease subunit [KO:K15586]
I6J16_04555  ABC transporter ATP-binding protein [KO:K15587] [EC:7.2.2.11]
I6J16_04560  ABC transporter ATP-binding protein [KO:K10824] [EC:7.2.2.11]
I6J16_03510  gsiB; glutathione ABC transporter substrate-binding protein GsiB [KO:K13889]
I6J16_03805  glutathione ABC transporter substrate-binding protein GsiB [KO:K13889]
I6J16_04090  glutathione ABC transporter substrate-binding protein [KO:K13889]
I6J16_05915  glutathione ABC transporter substrate-binding protein GsiB [KO:K13889]
I6J16_07305  gsiB; glutathione ABC transporter substrate-binding protein GsiB [KO:K13889]
I6J16_08100  glutathione ABC transporter substrate-binding protein [KO:K13889]
I6J16_00850  glutathione ABC transporter substrate-binding protein GsiB [KO:K13889]
I6J16_01600  gsiB; glutathione ABC transporter substrate-binding protein GsiB [KO:K13889]
I6J16_02865  gsiB; glutathione ABC transporter substrate-binding protein GsiB [KO:K13889]
I6J16_02860  gsiC; glutathione ABC transporter permease GsiC [KO:K13890]
I6J16_02855  gsiD; glutathione ABC transporter permease GsiD [KO:K13891]
I6J16_02870  dipeptide ABC transporter ATP-binding protein [KO:K13892]
I6J16_01775  ABC transporter substrate-binding protein [KO:K23227]
I6J16_01770  fhuB; Fe(3+)-hydroxamate ABC transporter permease FhuB [KO:K23228]
I6J16_01780  ABC transporter ATP-binding protein [KO:K10829] [EC:7.2.2.16]
I6J16_06745  zinc ABC transporter substrate-binding protein [KO:K09815]
I6J16_06755  metal ABC transporter permease [KO:K09816]
I6J16_06750  metal ABC transporter ATP-binding protein [KO:K09817] [EC:7.2.2.20]
I6J16_03665  cbiM; cobalt transporter CbiM [KO:K02007]
I6J16_03675  hypothetical protein [KO:K02008]
I6J16_03680  ABC transporter ATP-binding protein [KO:K02006]
I6J16_00615  DUF4198 domain-containing protein [KO:K10094]
I6J16_03660  DUF4198 domain-containing protein [KO:K10094]
I6J16_03670  hypothetical protein [KO:K16915]
I6J16_02135  energy-coupling factor transporter transmembrane protein EcfT [KO:K16785]
I6J16_00125  lipoprotein-releasing ABC transporter permease subunit [KO:K09808]
I6J16_00130  ABC transporter ATP-binding protein [KO:K09810] [EC:7.6.2.-]
I6J16_02580  ccmD; heme exporter protein CcmD [KO:K02196]
I6J16_02575  ccsA; cytochrome c biogenesis protein CcsA [KO:K02195]
I6J16_02570  ccmB; heme exporter protein CcmB [KO:K02194]
I6J16_02565  ccmA; cytochrome c biogenesis heme-transporting ATPase CcmA [KO:K02193] [EC:7.6.2.5]
I6J16_09665  lptF; LPS export ABC transporter permease LptF [KO:K07091]
I6J16_09660  lptG; LPS export ABC transporter permease LptG [KO:K11720]
I6J16_11170  lptB; LPS export ABC transporter ATP-binding protein [KO:K06861] [EC:7.5.2.5]
I6J16_11040  FtsX-like permease family protein [KO:K09811]
I6J16_11045  ATP-binding cassette domain-containing protein [KO:K09812]
I6J16_08825  msbA; lipid A export permease/ATP-binding protein MsbA [KO:K11085] [EC:7.5.2.6]
I6J16_03715  ABC transporter ATP-binding protein/permease [KO:K02471]
I6J16_04430  ABC transporter ATP-binding protein/permease [KO:K02471]
I6J16_04465  ABC transporter ATP-binding protein/permease [KO:K02471]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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