Entry
Name
ABC transporters - Thermosynechococcus sp. NK55
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Thermosynechococcus sp. NK55 [GN:
thn ]
Gene
NK55_00685 cysP; ABC-type sulfate/thiosulfate uptake system substrate-binding component CysP [KO:K23163 ]
NK55_00680 cysT; ABC-type sulfate/thiosulfate uptake system permease component CysT [KO:K02046 ]
NK55_00670 cysW; ABC-type sulfate/thiosulfate uptake system permease component CysW [KO:K02047 ]
NK55_02225 nrtA; ABC-type nitrate/nitrite uptake system substrate-binding protein NrtA [KO:K15576 ]
NK55_02230 nrtB; ABC-type nitrate/nitrite uptake system permease component NrtB [KO:K15577 ]
NK55_02240 nrtD; ABC-type nitrate/nitrite uptake system ATPase component NrtD [KO:K15579 ]
NK55_06690 cmpA; high-affinity ABC-type bicarbonate uptake system substrate-binding component CmpA [KO:K11950 ]
NK55_06695 cmpB; high-affinity ABC-type bicarbonate uptake system permease component CmpB [KO:K11951 ]
NK55_06705 cmpD; high-affinity ABC-type bicarbonate uptake system ATPase component CmpD [KO:K11953 ] [EC:7.3.2.-]
NK55_11575 futA; ABC-type FeII uptake system substrate-binding component FutA [KO:K02012 ]
NK55_05205 futB; ABC-type FeII uptake system permease component FutB [KO:K02011 ]
NK55_01225 ABC-type sugar transport system ATPase component [KO:K10112 ] [EC:7.5.2.-]
NK55_05440 ABC-type sugar uptake system ATPase component [KO:K10112 ] [EC:7.5.2.-]
NK55_07475 pstS; ABC-type phosphate uptake system substrate-binding component PstS [KO:K02040 ]
NK55_07480 pstC; ABC-type phosphate uptake system permease component PstC [KO:K02037 ]
NK55_07485 pstA; ABC-type phosphate uptake system permease component PstA [KO:K02038 ]
NK55_10965 ABC-type amino acid transport system substrate-binding component [KO:K01999 ]
NK55_05030 livH; ABC-type branched-chain amino acid uptake system permease component LivH [KO:K01997 ]
NK55_11740 livM; branched-chain amino acid transport system permease protein LivM [KO:K01998 ]
NK55_07235 livG; ABC-type branched-chain amino acid uptake system ATPase component LivG [KO:K01995 ]
NK55_06715 livF; ABC-type branched-chain amino acid transport system ATPase component LivF [KO:K01996 ]
NK55_03150 natC; ABC-type netural amino acid transport system permease component NatC [KO:K11955 ]
NK55_04765 natD; ABC-type netural amino acid transport system permease protein NatD [KO:K11956 ]
NK55_03155 natA; ABC-type neutral amino acid transport system ATPase component NatA [KO:K11957 ]
NK55_09490 natE; ABC-type neutral amino acid uptake sytem ATPase component NatE [KO:K11958 ]
NK55_00205 urtA; ABC-type high affinity urea uptake system substrate-binding component UrtA [KO:K11959 ]
NK55_00200 urtB; ABC-type high affinity urea uptake system permease component UrtB [KO:K11960 ]
NK55_00195 urtC; ABC-type high affinity urea uptake system permease component UrtC [KO:K11961 ]
NK55_00190 urtD; ABC-type high affinity urea uptake system ATPase component UrtD [KO:K11962 ]
NK55_00185 urtE; ABC-type high affinity urea uptake system ATPase component UrtE [KO:K11963 ]
NK55_10605 mntC; ABC-type Zn/Mn uptake system substrate-binding component MntC [KO:K11601 ]
NK55_11540 mtrB; ABC-type Zn/Mn uptake system permease component MntB [KO:K11602 ]
NK55_08315 zntA; ABC-type zinc uptake system substrate-binding component ZntA [KO:K09815 ]
NK55_08670 zntB; ABC-type zinc uptake system permease component ZntB [KO:K09816 ]
NK55_02535 nikM; ECF-type nickel uptake system substrate-binding component NikM [KO:K02007 ]
NK55_00785 cbiM; ECF-type cobalt transport system substrate-binding component CbiM [KO:K02007 ]
NK55_00795 cbiQ; ECF-type cobalt transport system permease component CbiQ [KO:K02008 ]
NK55_06890 nikQ; ECF-type nickel uptake system permease component of energizing module NikQ [KO:K02008 ]
NK55_00800 cbiO; ECF-type cobalt transport system ATPase component CbiO [KO:K02006 ]
NK55_03265 nikO; ECF-type nickel uptake system ATPase component NikO [KO:K02006 ]
NK55_02540 nikL; ECF-type nickel uptake system accessory component NikL [KO:K16915 ]
NK55_11075 bioY; ECF-type transport system substrate-specific component BioY [KO:K03523 ]
NK55_00695 sfuC; ABC-type iron(III)-transport system ATPase component SfuC [KO:K16787 ] [EC:7.-.-.-]
NK55_04490 lptG; ABC-type lipopolysaccharide export system permease component LptG [KO:K11720 ]
NK55_09435 lptF; ABC-type lipopolysaccharide export system permease component LptF [KO:K11720 ]
NK55_07100 ftsE-2; ABC-type septal ring translocating system ATPase component FtsE [KO:K09812 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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