PATHWAY: ttl02010 Help
Entry
Name
ABC transporters - Thermus thermophilus JL-18
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Thermus thermophilus JL-18 [GN:
ttl ]
Gene
TtJL18_2105 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [KO:K15553 ]
TtJL18_1278 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [KO:K15553 ]
TtJL18_1280 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [KO:K15554 ]
TtJL18_2106 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [KO:K15554 ]
TtJL18_1331 molybdenum ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
TtJL18_0810 ABC-type spermidine/putrescine transport system, permease component II [KO:K11070 ]
TtJL18_0809 ABC-type spermidine/putrescine transport system, permease component I [KO:K11071 ]
TtJL18_1601 ABC-type proline/glycine betaine transport system, periplasmic component [KO:K02002 ]
TtJL18_1600 ABC-type proline/glycine betaine transport system, permease component [KO:K02001 ]
TtJL18_0961 putative ABC-type transport system, periplasmic component/surface lipoprotein [KO:K07335 ]
TtJL18_0749 putative ABC-type transport system, periplasmic component/surface lipoprotein [KO:K07335 ]
TtJL18_1949 ABC-type uncharacterized transport system, permease component [KO:K23535 ]
TtJL18_0747 ABC-type uncharacterized transport system, permease component [KO:K23535 ]
TtJL18_0718 ABC-type branched-chain amino acid transport system, periplasmic component [KO:K01999 ]
TtJL18_1372 ABC-type branched-chain amino acid transport system, periplasmic component [KO:K01999 ]
TtJL18_1486 ABC-type branched-chain amino acid transport system, periplasmic component [KO:K01999 ]
TtJL18_1630 ABC-type branched-chain amino acid transport system, periplasmic component [KO:K01999 ]
TtJL18_1089 ABC-type branched-chain amino acid transport system, periplasmic component [KO:K01999 ]
TtJL18_2186 ABC-type branched-chain amino acid transport system, periplasmic component [KO:K01999 ]
TtJL18_2189 ABC-type branched-chain amino acid transport system, periplasmic component [KO:K01999 ]
TtJL18_0717 branched-chain amino acid ABC-type transport system, permease component [KO:K01997 ]
TtJL18_1373 branched-chain amino acid ABC-type transport system, permease component [KO:K01997 ]
TtJL18_2190 branched-chain amino acid ABC-type transport system, permease component [KO:K01997 ]
TtJL18_1487 branched-chain amino acid ABC-type transport system, permease component [KO:K01997 ]
TtJL18_1632 branched-chain amino acid ABC-type transport system, permease component [KO:K01997 ]
TtJL18_1088 branched-chain amino acid ABC-type transport system, permease component [KO:K01997 ]
TtJL18_2185 branched-chain amino acid ABC-type transport system, permease component [KO:K01997 ]
TtJL18_2184 ABC-type branched-chain amino acid transport system, permease component [KO:K01998 ]
TtJL18_1374 ABC-type branched-chain amino acid transport system, permease component [KO:K01998 ]
TtJL18_2191 ABC-type branched-chain amino acid transport system, permease component [KO:K01998 ]
TtJL18_1491 ABC-type branched-chain amino acid transport system, permease component [KO:K01998 ]
TtJL18_0716 ABC-type branched-chain amino acid transport system, permease component [KO:K01998 ]
TtJL18_1631 ABC-type branched-chain amino acid transport system, permease component [KO:K01998 ]
TtJL18_0715 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995 ]
TtJL18_1375 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995 ]
TtJL18_2193 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995 ]
TtJL18_1489 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995 ]
TtJL18_1634 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995 ]
TtJL18_2183 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995 ]
TtJL18_1086 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996 ]
TtJL18_2182 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996 ]
TtJL18_1376 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996 ]
TtJL18_2194 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996 ]
TtJL18_1488 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996 ]
TtJL18_0714 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996 ]
TtJL18_1629 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996 ]
TtJL18_1480 ABC-type metal ion transport system, periplasmic component/surface adhesin [KO:K09815 ]
TtJL18_0192 ABC-type transport system, involved in lipoprotein release, permease component [KO:K09808 ]
TtJL18_1103 ABC-type transport system, involved in lipoprotein release, permease component [KO:K09808 ]
TtJL18_0611 ABC-type antimicrobial peptide transport system, ATPase component [KO:K09810 ] [EC:7.6.2.-]
TtJL18_0641 ABC-type transport system involved in cytochrome c biogenesis, permease component [KO:K02195 ]
TtJL18_0640 ABC-type transport system involved in cytochrome c biogenesis, permease component [KO:K02194 ]
TtJL18_0707 ABC-type multidrug transport system, ATPase and permease component [KO:K18889 ]
TtJL18_0708 ABC-type multidrug transport system, ATPase and permease component [KO:K18890 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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