KEGG   PATHWAY: zju04626
Entry
zju04626                    Pathway                                
Name
Plant-pathogen interaction - Ziziphus jujuba (Chinese jujube)
Description
Plants lack animal-like adaptive immunity mechanisms, and therefore have evolved a specific system with multiple layers against invading pathogens. The primary response includes the perception of pathogens by cell-surface pattern-recognition receptors (PRRs) and is referred to as PAMP-triggered immunity (PTI). Activation of FLS2 and EFR triggers MAPK signaling pathway that activates defense genes for antimictobial compounds. The increase in the cytosolic Ca2+ concentration is also a regulator for production of reactive oxygen species and localized programmed cell death/hypersensitive response. The secondary response is called effector-triggered immunity (ETI). Pathogens can acquire the ability to suppress PTI by directly injecting effector proteins into the plant cell through secretion systems. In addition, pathogens can manipulate plant hormone signaling pathways to evade host immune responses using coronatine toxin. Some plants possess specific intracellular surveillance proteins (R proteins) to monitor the presence of pathogen virulence proteins. This ETI occurs with localized programmed cell death to arrest pathogen growth, resulting in cultivar-specific disease resistance.
Class
Organismal Systems; Environmental adaptation
Pathway map
zju04626  Plant-pathogen interaction
zju04626

Organism
Ziziphus jujuba (Chinese jujube) [GN:zju]
Gene
132799159  calcium-dependent protein kinase 10-like [KO:K13412] [EC:2.7.11.1]
107410708  calcium-dependent protein kinase 34 [KO:K13412] [EC:2.7.11.1]
107412614  calcium-dependent protein kinase 8 [KO:K13412] [EC:2.7.11.1]
107427186  calcium-dependent protein kinase 26 [KO:K13412] [EC:2.7.11.1]
107430482  calcium-dependent protein kinase 11 [KO:K13412] [EC:2.7.11.1]
107433607  calcium-dependent protein kinase 20 [KO:K13412] [EC:2.7.11.1]
107433642  calcium-dependent protein kinase 26 [KO:K13412] [EC:2.7.11.1]
107430894  calcium-dependent protein kinase 13 isoform X1 [KO:K13412] [EC:2.7.11.1]
107430235  calcium-dependent protein kinase 1 [KO:K13412] [EC:2.7.11.1]
107432385  calcium-dependent protein kinase 32 [KO:K13412] [EC:2.7.11.1]
107433024  calcium-dependent protein kinase 2 [KO:K13412] [EC:2.7.11.1]
107415799  calcium-dependent protein kinase SK5 [KO:K13412] [EC:2.7.11.1]
107435963  calcium-dependent protein kinase 24 [KO:K13412] [EC:2.7.11.1]
107412864  calcium and calcium/calmodulin-dependent serine/threonine-protein kinase [KO:K13412] [EC:2.7.11.1]
107419468  calcium-dependent protein kinase 2 [KO:K13412] [EC:2.7.11.1]
107422810  calcium-dependent protein kinase 29 isoform X2 [KO:K13412] [EC:2.7.11.1]
107430444  calcium-dependent protein kinase 1 [KO:K13412] [EC:2.7.11.1]
107424366  calcium-dependent protein kinase 28 isoform X1 [KO:K13412] [EC:2.7.11.1]
107410604  CDPK-related kinase 5 [KO:K13412] [EC:2.7.11.1]
107403952  CDPK-related kinase 7 isoform X1 [KO:K13412] [EC:2.7.11.1]
107411193  CDPK-related protein kinase isoform X1 [KO:K13412] [EC:2.7.11.1]
107423691  CDPK-related kinase 3 [KO:K13412] [EC:2.7.11.1]
107415003  CDPK-related kinase 4 [KO:K13412] [EC:2.7.11.1]
107404860  respiratory burst oxidase homolog protein A [KO:K13447] [EC:1.6.3.- 1.11.1.-]
107407641  respiratory burst oxidase homolog protein E [KO:K13447] [EC:1.6.3.- 1.11.1.-]
107419049  respiratory burst oxidase homolog protein A [KO:K13447] [EC:1.6.3.- 1.11.1.-]
107411938  respiratory burst oxidase homolog protein B [KO:K13447] [EC:1.6.3.- 1.11.1.-]
107411852  respiratory burst oxidase homolog protein B [KO:K13447] [EC:1.6.3.- 1.11.1.-]
107424617  respiratory burst oxidase homolog protein D [KO:K13447] [EC:1.6.3.- 1.11.1.-]
107415600  cyclic nucleotide-gated ion channel 17 isoform X1 [KO:K27629]
125422339  probable cyclic nucleotide-gated ion channel 20, chloroplastic isoform X1 [KO:K05391]
107405533  putative cyclic nucleotide-gated ion channel 8 [KO:K05391]
107408278  probable cyclic nucleotide-gated ion channel 16 [KO:K05391]
107411379  protein CNGC15b [KO:K05391]
107414564  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
107414607  cyclic nucleotide-gated ion channel 1 isoform X1 [KO:K05391]
107419549  probable cyclic nucleotide-gated ion channel 20, chloroplastic isoform X1 [KO:K05391]
107415358  cyclic nucleotide-gated ion channel 18 [KO:K05391]
107423657  cyclic nucleotide-gated ion channel 1 [KO:K05391]
107431258  cyclic nucleotide-gated ion channel 1 [KO:K05391]
107414602  cyclic nucleotide-gated ion channel 1 [KO:K05391]
107415943  cyclic nucleotide-gated ion channel 2 isoform X1 [KO:K05391]
107414103  cyclic nucleotide-gated ion channel 2-like isoform X1 [KO:K05391]
107426320  protein CNGC15b [KO:K05391]
107414549  cyclic nucleotide-gated ion channel 1 isoform X1 [KO:K05391]
107414573  cyclic nucleotide-gated ion channel 1 [KO:K05391]
107414578  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
107414583  cyclic nucleotide-gated ion channel 1 isoform X1 [KO:K05391]
107429923  probable cyclic nucleotide-gated ion channel 14 [KO:K05391]
107426524  probable cyclic nucleotide-gated ion channel 5 [KO:K05391]
107414561  cyclic nucleotide-gated ion channel 1 [KO:K05391]
107414597  cyclic nucleotide-gated ion channel 1 [KO:K05391]
107430493  cyclic nucleotide-gated ion channel 4 [KO:K05391]
107429008  probable calcium-binding protein CML45 [KO:K02183]
107425895  calmodulin-3 [KO:K02183]
132799064  calmodulin-7 [KO:K02183]
107419490  calmodulin [KO:K02183]
107418972  calcium-binding protein CP1 [KO:K02183]
107423402  LOW QUALITY PROTEIN: calmodulin-7 [KO:K02183]
107423403  calmodulin-7 [KO:K02183]
107423405  calmodulin-7 [KO:K02183]
107415541  probable calcium-binding protein CML45 [KO:K02183]
107404544  putative calcium-binding protein CML19 [KO:K13448]
125423431  probable calcium-binding protein CML22 isoform X1 [KO:K13448]
107409684  probable calcium-binding protein CML48 isoform X2 [KO:K13448]
107409714  probable calcium-binding protein CML41 [KO:K13448]
125423840  calmodulin-like protein 30 [KO:K13448]
107413144  calmodulin-like protein 8 isoform X1 [KO:K13448]
125424254  putative calcium-binding protein CML23 [KO:K13448]
107420771  probable calcium-binding protein CML13 [KO:K13448]
107418418  polcalcin Bra n 2-like [KO:K13448]
107431634  calcium-binding protein CBP [KO:K13448]
107429541  probable calcium-binding protein CML16 [KO:K13448]
107421107  probable calcium-binding protein CML44 [KO:K13448]
107427722  calmodulin-like protein 3 [KO:K13448]
107414852  probable calcium-binding protein CML18 [KO:K13448]
107424787  caltractin [KO:K13448]
107422102  calmodulin-like protein 3 [KO:K13448]
107416249  calcium-binding protein CML24 [KO:K13448]
107417331  probable calcium-binding protein CML21 [KO:K13448]
107434111  probable calcium-binding protein CML27 [KO:K13448]
107416401  polcalcin Bet V 4 [KO:K13448]
107433800  probable calcium-binding protein CML36 [KO:K13448]
107431195  probable calcium-binding protein CML17 [KO:K13448]
107418957  probable calcium-binding protein CML15 [KO:K13448]
107424823  probable calcium-binding protein CML41 [KO:K13448]
107424831  probable calcium-binding protein CML41 [KO:K13448]
107429242  probable calcium-binding protein CML25 [KO:K13448]
107431392  calcium-binding allergen Bet V 3 [KO:K13448]
107417689  calcium-binding protein CML38 [KO:K13448]
107408397  NO-associated protein 1, chloroplastic/mitochondrial isoform X1 [KO:K13427] [EC:1.14.13.39]
107432958  mitogen-activated protein kinase homolog MMK2 [KO:K20600] [EC:2.7.11.24]
132799228  uncharacterized protein LOC132799228 [KO:K13416] [EC:2.7.10.1 2.7.11.1]
107427530  BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1-like [KO:K13416] [EC:2.7.10.1 2.7.11.1]
107427529  BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 isoform X2 [KO:K13416] [EC:2.7.10.1 2.7.11.1]
107427533  BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 isoform X1 [KO:K13416] [EC:2.7.10.1 2.7.11.1]
107418301  elongation factor Tu, chloroplastic [KO:K02358]
107425993  elongation factor Tu, mitochondrial [KO:K02358]
107423232  elongation factor Tu, mitochondrial isoform X1 [KO:K02358]
107435014  mitogen-activated protein kinase kinase kinase 1 [KO:K13414] [EC:2.7.11.25]
107432800  mitogen-activated protein kinase kinase 6 [KO:K04368] [EC:2.7.12.2]
107411280  mitogen-activated protein kinase 3 isoform X1 [KO:K20536] [EC:2.7.11.24]
107407108  mitogen-activated protein kinase homolog MMK1 [KO:K14512] [EC:2.7.11.24]
107431286  probable WRKY transcription factor 33 [KO:K13424]
107432879  WRKY transcription factor 22 [KO:K13425]
107432881  WRKY transcription factor 22 [KO:K13425]
107407412  glycerol kinase [KO:K00864] [EC:2.7.1.30]
132799475  pathogenesis-related protein 1-like [KO:K13449]
112492872  basic form of pathogenesis-related protein 1-like [KO:K13449]
132799401  pathogenesis-related protein 1-like [KO:K13449]
125424133  pathogenesis-related protein 1 [KO:K13449]
107427439  LOW QUALITY PROTEIN: basic form of pathogenesis-related protein 1 [KO:K13449]
107427102  basic form of pathogenesis-related protein 1 [KO:K13449]
107427126  basic form of pathogenesis-related protein 1 [KO:K13449]
107427101  pathogenesis-related protein 1 [KO:K13449]
107411165  pathogenesis-related genes transcriptional activator PTI5-like [KO:K13433]
107411595  pathogenesis-related genes transcriptional activator PTI6 [KO:K13434]
107426175  pto-interacting protein 1 [KO:K13436] [EC:2.7.11.1]
107422118  PTI1-like tyrosine-protein kinase 1 isoform X1 [KO:K13436] [EC:2.7.11.1]
107433323  pto-interacting protein 1 isoform X1 [KO:K13436] [EC:2.7.11.1]
107414506  RPM1-interacting protein 4 [KO:K13456]
107422274  RPM1-interacting protein 4 isoform X1 [KO:K13456]
107426810  RPM1-interacting protein 4 [KO:K13456]
132804515  disease resistance protein RPM1-like [KO:K13457]
125423544  disease resistance protein RPM1-like [KO:K13457]
107416591  disease resistance protein RPM1-like isoform X1 [KO:K13457]
125423576  disease resistance protein RPM1-like [KO:K13457]
132800348  disease resistance protein RPM1-like [KO:K13457]
107416621  disease resistance protein RPM1-like [KO:K13457]
107416851  disease resistance protein RPM1-like [KO:K13457]
132799443  disease resistance protein RPM1-like [KO:K13457]
125420285  disease resistance protein RPM1-like [KO:K13457]
132799437  disease resistance protein RPM1-like [KO:K13457]
107404932  disease resistance protein RPM1 [KO:K13457]
107421678  disease resistance protein RPM1-like [KO:K13457]
125419124  disease resistance protein RPM1 isoform X1 [KO:K13457]
125418181  disease resistance protein RPM1 [KO:K13457]
107403607  disease resistance protein RPM1-like [KO:K13457]
107403736  disease resistance protein RPM1-like [KO:K13457]
107404934  disease resistance protein RPM1 [KO:K13457]
107430464  disease resistance protein RPM1-like isoform X1 [KO:K13457]
107416091  disease resistance protein RPM1-like [KO:K13457]
107421686  disease resistance protein RPM1-like [KO:K13457]
107430186  disease resistance protein RPM1-like [KO:K13457]
107423471  disease resistance protein RPM1 [KO:K13457]
107416818  disease resistance protein RPM1-like [KO:K13457]
107434534  disease resistance protein RPM1-like isoform X1 [KO:K13457]
107434542  disease resistance protein RPM1 [KO:K13457]
107430574  disease resistance protein RPM1 isoform X2 [KO:K13457]
107434565  disease resistance protein RPM1-like [KO:K13457]
107434569  disease resistance protein RPM1 [KO:K13457]
107435805  disease resistance protein RPM1-like isoform X1 [KO:K13457]
107409838  disease resistance protein RPM1-like [KO:K13457]
107414260  cysteine and histidine-rich domain-containing protein RAR1 [KO:K13458]
107418901  cysteine and histidine-rich domain-containing protein RAR1-like [KO:K13458]
107430178  protein SGT1 homolog A isoform X1 [KO:K12795]
107414676  protein SGT1 homolog [KO:K12795]
107416986  heat shock protein 90-6, mitochondrial [KO:K09487]
107429130  heat shock protein 90-5, chloroplastic [KO:K09487]
107420419  endoplasmin homolog [KO:K09487]
107430166  heat shock protein 83 [KO:K04079]
107430207  heat shock protein 83 [KO:K04079]
107416736  heat shock cognate protein 80 [KO:K04079]
132803057  probable disease resistance protein At4g27220 [KO:K13459]
125423628  probable disease resistance protein At4g27220 isoform X1 [KO:K13459]
112489063  probable disease resistance protein At4g27220 [KO:K13459]
107424070  disease resistance protein RPS2 [KO:K13459]
107412684  disease resistance protein At4g27190 [KO:K13459]
112490559  disease resistance protein At4g27190 [KO:K13459]
107431421  disease resistance protein At4g27190 [KO:K13459]
112490607  disease resistance protein At4g27190 [KO:K13459]
107431475  disease resistance protein At4g27190 [KO:K13459]
107425628  probable disease resistance protein At4g27220 [KO:K13459]
107432981  probable disease resistance protein At4g27220 [KO:K13459]
107434778  probable disease resistance protein At4g27220 [KO:K13459]
107428451  probable disease resistance protein At4g27220 [KO:K13459]
112491001  probable disease resistance protein At4g27220 [KO:K13459]
107430202  probable disease resistance protein At4g27220 isoform X1 [KO:K13459]
107433397  probable disease resistance protein At4g27220 [KO:K13459]
107433444  probable disease resistance protein At4g27220 [KO:K13459]
107429924  disease resistance protein At4g27190 [KO:K13459]
107428019  serine/threonine-protein kinase PBS1 [KO:K13430] [EC:2.7.11.1]
107417665  serine/threonine-protein kinase PBS1 [KO:K13430] [EC:2.7.11.1]
107413362  probable cysteine protease RD19D [KO:K01373] [EC:3.4.22.41]
107420476  cysteine proteinase 15A [KO:K01373] [EC:3.4.22.41]
107426701  cysteine protease RD19A [KO:K01373] [EC:3.4.22.41]
107403372  3-ketoacyl-CoA synthase 4 [KO:K15397] [EC:2.3.1.199]
112491970  3-ketoacyl-CoA synthase 11 [KO:K15397] [EC:2.3.1.199]
107411224  3-ketoacyl-CoA synthase 12-like [KO:K15397] [EC:2.3.1.199]
132799226  3-ketoacyl-CoA synthase 7 [KO:K15397] [EC:2.3.1.199]
107413152  3-ketoacyl-CoA synthase 11 [KO:K15397] [EC:2.3.1.199]
107413576  3-ketoacyl-CoA synthase 19 [KO:K15397] [EC:2.3.1.199]
107413579  3-ketoacyl-CoA synthase 19 [KO:K15397] [EC:2.3.1.199]
107413586  3-ketoacyl-CoA synthase 19 [KO:K15397] [EC:2.3.1.199]
107432925  3-ketoacyl-CoA synthase 20 [KO:K15397] [EC:2.3.1.199]
107429439  3-ketoacyl-CoA synthase 6 [KO:K15397] [EC:2.3.1.199]
107420173  3-ketoacyl-CoA synthase 10 [KO:K15397] [EC:2.3.1.199]
107423860  3-ketoacyl-CoA synthase 1 [KO:K15397] [EC:2.3.1.199]
107435253  3-ketoacyl-CoA synthase 2 [KO:K15397] [EC:2.3.1.199]
107414370  3-ketoacyl-CoA synthase 5 [KO:K15397] [EC:2.3.1.199]
107417649  3-ketoacyl-CoA synthase 15 isoform X1 [KO:K15397] [EC:2.3.1.199]
107432383  3-ketoacyl-CoA synthase 11 [KO:K15397] [EC:2.3.1.199]
107432975  3-ketoacyl-CoA synthase 20 [KO:K15397] [EC:2.3.1.199]
107420263  3-ketoacyl-CoA synthase 4 isoform X1 [KO:K15397] [EC:2.3.1.199]
107417003  WRKY transcription factor 1 [KO:K18834]
107412508  WRKY transcription factor SUSIBA2 [KO:K18835]
107417519  probable WRKY transcription factor 2 [KO:K18835]
125423350  receptor-like protein EIX2 [KO:K13466]
107421900  receptor-like protein EIX2 [KO:K13466]
107423984  receptor-like protein EIX2 [KO:K13466]
107420127  LysM domain receptor-like kinase 3 [KO:K13429]
107406309  LysM domain receptor-like kinase 3 [KO:K13429]
Compound
C00027  Hydrogen peroxide
C00076  Calcium cation
C00533  Nitric oxide
C00704  Superoxide
C16844  Hydroxyl radical
Reference
PMID:18206360
  Authors
Zipfel C
  Title
Pattern-recognition receptors in plant innate immunity.
  Journal
Curr Opin Immunol 20:10-6 (2008)
DOI:10.1016/j.coi.2007.11.003
Reference
PMID:19748302
  Authors
Chinchilla D, Shan L, He P, de Vries S, Kemmerling B
  Title
One for all: the receptor-associated kinase BAK1.
  Journal
Trends Plant Sci 14:535-41 (2009)
DOI:10.1016/j.tplants.2009.08.002
Reference
PMID:19423812
  Authors
Boller T, He SY
  Title
Innate immunity in plants: an arms race between pattern recognition receptors in plants and effectors in microbial pathogens.
  Journal
Science 324:742-4 (2009)
DOI:10.1126/science.1171647
Reference
PMID:19794842
  Authors
Ma W, Smigel A, Verma R, Berkowitz GA
  Title
Cyclic nucleotide gated channels and related signaling components in plant innate immunity.
  Journal
Plant Signal Behav 4:277-82 (2009)
DOI:10.4161/psb.4.4.8103
Reference
PMID:11875555
  Authors
Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J
  Title
MAP kinase signalling cascade in Arabidopsis innate immunity.
  Journal
Nature 415:977-83 (2002)
DOI:10.1038/415977a
Reference
PMID:15922649
  Authors
Zipfel C, Felix G
  Title
Plants and animals: a different taste for microbes?
  Journal
Curr Opin Plant Biol 8:353-60 (2005)
DOI:10.1016/j.pbi.2005.05.004
Reference
PMID:17451411
  Authors
He P, Shan L, Sheen J
  Title
Elicitation and suppression of microbe-associated molecular pattern-triggered immunity in plant-microbe interactions.
  Journal
Cell Microbiol 9:1385-96 (2007)
DOI:10.1111/j.1462-5822.2007.00944.x
Reference
PMID:17876517
  Authors
de Wit PJ
  Title
How plants recognize pathogens and defend themselves.
  Journal
Cell Mol Life Sci 64:2726-32 (2007)
DOI:10.1007/s00018-007-7284-7
Reference
PMID:16497589
  Authors
Chisholm ST, Coaker G, Day B, Staskawicz BJ
  Title
Host-microbe interactions: shaping the evolution of the plant immune response.
  Journal
Cell 124:803-14 (2006)
DOI:10.1016/j.cell.2006.02.008
Reference
PMID:16677430
  Authors
McHale L, Tan X, Koehl P, Michelmore RW
  Title
Plant NBS-LRR proteins: adaptable guards.
  Journal
Genome Biol 7:212 (2006)
DOI:10.1186/gb-2006-7-4-212
Reference
PMID:11459065
  Authors
Dangl JL, Jones JD
  Title
Plant pathogens and integrated defence responses to infection.
  Journal
Nature 411:826-33 (2001)
DOI:10.1038/35081161
Reference
PMID:17108957
  Authors
Jones JD, Dangl JL
  Title
The plant immune system.
  Journal
Nature 444:323-9 (2006)
DOI:10.1038/nature05286
Reference
PMID:16697674
  Authors
da Cunha L, McFall AJ, Mackey D
  Title
Innate immunity in plants: a continuum of layered defenses.
  Journal
Microbes Infect 8:1372-81 (2006)
DOI:10.1016/j.micinf.2005.12.018
Reference
PMID:15862106
  Authors
Mudgett MB
  Title
New insights to the function of phytopathogenic bacterial type III effectors in plants.
  Journal
Annu Rev Plant Biol 56:509-31 (2005)
DOI:10.1146/annurev.arplant.56.032604.144218
Reference
PMID:17714518
  Authors
Ma W, Berkowitz GA
  Title
The grateful dead: calcium and cell death in plant innate immunity.
  Journal
Cell Microbiol 9:2571-85 (2007)
DOI:10.1111/j.1462-5822.2007.01031.x
Reference
PMID:14711430
  Authors
Schulze-Lefert P
  Title
Plant immunity: the origami of receptor activation.
  Journal
Curr Biol 14:R22-4 (2004)
DOI:10.1016/j.cub.2003.12.017
Reference
PMID:9868361
  Authors
Van der Biezen EA, Jones JD
  Title
Plant disease-resistance proteins and the gene-for-gene concept.
  Journal
Trends Biochem Sci 23:454-6 (1998)
DOI:10.1016/S0968-0004(98)01311-5
Reference
PMID:16936700
  Authors
Abramovitch RB, Anderson JC, Martin GB
  Title
Bacterial elicitation and evasion of plant innate immunity.
  Journal
Nat Rev Mol Cell Biol 7:601-11 (2006)
DOI:10.1038/nrm1984
Related
pathway
zju04144  Endocytosis
KO pathway
ko04626   
LinkDB

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