Paraburkholderia sp. 22B1P: PBP221_33220
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Entry
PBP221_33220 CDS
T10680
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
pazz Paraburkholderia sp. 22B1P
Pathway
pazz00909
Sesquiterpenoid and triterpenoid biosynthesis
pazz01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
pazz00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
PBP221_33220 (shc)
Enzymes [BR:
pazz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
PBP221_33220 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
PBP221_33220 (shc)
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
TED_complement
Pec_lyase
Motif
Other DBs
NCBI-ProteinID:
BEU23182
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Position
2:16897..18930
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AA seq
677 aa
AA seq
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MNDLSMTQTLGDALPQTLIDDHAPVAAALAAGATPVDALDAAVTRATDAILAAQKDDGHW
VYELEADATIPAEYVLLVHYLGETPNVELEQKIARYLRRIQLADGGWPLFTDGAMDVSAS
VKAYFALKMIGDPVDAEHMVRARECILAHGGAEAANVFTRILLALFGVVTWYAVPMMPVE
IMLLPKWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRGVRIDELFRGAPVTTGLLPR
SGHQSKSWFAFFRAVDGVLRVTDGLFPKRSRERAIKAAVDFVDERLNGEDGLGAIFPAMA
NSVMMYDVLGYPADHPKRAIARQSIDKLLVIGEEEAYCQPCLSPVWDTSLAAHALLETGD
TRAEEAAERGLAWLRPLQILDVRGDWISRRPDVRPGGWAFQYNNAHYPDVDDTAVVALAM
HRSAALTQSDVDANAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPP
TADVSGRCLSMLAQLGEMPATSEPARRAYDYLLKEQEDDGSWYGRWGMNYIYGTWTALCA
LNAAGISHDDARIKRAAQWLVSIQNADGGWGEDGTSYKLDYRGYEKAESIPSQTAWALLG
LMAVGYVDHPAVARGIEYLQGEQRDHGLWDETRFSATGFPRVFYLRYHGYRKFFPLWALA
RYRNLTRADQKRVAFGL
NT seq
2034 nt
NT seq
+upstream
nt +downstream
nt
atgaatgatttatccatgacccagacgctgggcgacgcactgcctcaaacgctgatcgac
gaccacgctcccgtggccgccgcgctggcggcaggcgccacgcccgtcgatgcgctcgac
gccgccgtcacgcgcgcgacggacgccatcctcgcggcgcaaaaggacgacggccactgg
gtctacgaactcgaagccgacgcgacgattcccgccgaatacgtgctgctcgtccactac
ctgggcgaaacgcccaacgtcgagctcgaacagaagattgcgcgctacctgcgccgcatc
cagctggccgacggcggctggccgctcttcaccgacggcgcgatggacgtcagcgcgagc
gtgaaagcctacttcgcgctgaaaatgatcggcgatcccgtcgacgccgagcacatggtc
cgcgcacgcgagtgcattctggcgcacggtggcgcggaagcggcgaacgtgttcacgcgc
atcctgctcgcgctgttcggcgtcgtcacgtggtacgcggtgccgatgatgcccgtcgaa
atcatgctgctgcccaagtggttcccgttccacctgtcgaaggtgtcgtactgggcgcgc
acggtgatcgtcccgctgctggtgctgaacgcgaagcggccggtcgcgcgcaatccgcgt
ggcgtgcgcatcgacgaactgttccgtggcgcgcccgtcacgacgggtctgctgccgcgc
tcgggccaccagagcaagagctggttcgcgttcttccgcgccgtcgacggcgtgctgcgc
gtgacggacggcctgttcccgaagcgttcgcgtgagcgcgcgatcaaggcggccgtcgat
ttcgtcgatgagcgcctgaacggcgaagacggcctcggcgcgattttcccggcgatggcg
aactccgtgatgatgtacgacgtgctcggttaccccgccgatcacccgaagcgcgcgatc
gcccgccagtcgatcgacaagctgctcgtcatcggcgaagaagaagcgtattgccagccg
tgcctgtcgcctgtgtgggacacgtcgctcgcggcgcatgcgctgctcgaaaccggcgac
acgcgcgccgaggaagccgccgagcgcggtctcgcgtggctgcgtccgctgcagattctc
gatgtgcgcggcgactggatttcgcgccgtcccgacgtgcgtccgggcggctgggcgttc
cagtacaacaacgcgcattaccccgacgtcgacgatacggccgtggtcgcgctggcgatg
catcgttcggcggcgctgacgcaatcggatgtcgacgcgaacgcgattgcccgcgcccgc
gaatgggtggtcggcatgcagagcagcgacggcgggtggggcgcgttcgagccggagaac
acgcagtactacctgaacaacattccgttctccgatcacggcgccttgctcgatccgccg
accgccgacgtgtccggccgttgcctgtcgatgctcgcgcaactcggcgaaatgccagcg
accagcgagcccgcgcgccgcgcctacgactatctgctgaaagagcaggaagacgacggc
agctggtacggccgctggggcatgaactacatctacggcacgtggacggcgctgtgcgcg
ctgaacgccgcgggcatctcgcatgacgacgcgcgcatcaagcgcgccgcgcagtggctc
gtatcgattcagaacgcggacggcggctggggcgaagacggcaccagctacaagctcgac
tatcgcggctacgagaaggccgaaagcattccgtcgcaaacggcgtgggcgctactcggc
ctgatggccgtcggctatgtcgatcatcccgccgtcgcgcgcggtatcgaatatctgcag
ggcgagcagcgagatcacggcctgtgggacgaaacgcgcttctcggcaacaggcttcccg
cgcgtgttctatctgcgctatcacgggtatcgcaagttcttcccgctgtgggcgctcgcg
cgctaccgcaacctgacgcgcgcggatcagaagcgcgtcgccttcggcttgtga
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