Prionailurus bengalensis (leopard cat): 122470240
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Entry
122470240 CDS
T07574
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg04014
Ras signaling pathway
pbg04072
Phospholipase D signaling pathway
pbg04148
Efferocytosis
pbg04360
Axon guidance
pbg04625
C-type lectin receptor signaling pathway
pbg04630
JAK-STAT signaling pathway
pbg04650
Natural killer cell mediated cytotoxicity
pbg04660
T cell receptor signaling pathway
pbg04670
Leukocyte transendothelial migration
pbg04722
Neurotrophin signaling pathway
pbg04920
Adipocytokine signaling pathway
pbg04931
Insulin resistance
pbg05168
Herpes simplex virus 1 infection
pbg05205
Proteoglycans in cancer
pbg05208
Chemical carcinogenesis - reactive oxygen species
pbg05211
Renal cell carcinoma
pbg05220
Chronic myeloid leukemia
pbg05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
122470240 (PTPN11)
04630 JAK-STAT signaling pathway
122470240 (PTPN11)
04072 Phospholipase D signaling pathway
122470240 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
122470240 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
122470240 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
122470240 (PTPN11)
04660 T cell receptor signaling pathway
122470240 (PTPN11)
04670 Leukocyte transendothelial migration
122470240 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
122470240 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
122470240 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
122470240 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
122470240 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
122470240 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
122470240 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
122470240 (PTPN11)
05211 Renal cell carcinoma
122470240 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
122470240 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
122470240 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
pbg01009
]
122470240 (PTPN11)
Enzymes [BR:
pbg01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
122470240 (PTPN11)
Protein phosphatases and associated proteins [BR:
pbg01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
122470240 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
Y_phosphatase3
PTPlike_phytase
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
122470240
NCBI-ProteinID:
XP_043413586
LinkDB
All DBs
Position
D3:10099016..10178805
Genome browser
AA seq
597 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDECALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW
QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI
DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK
RKGHEYTNIKYSLTDQTSGDQSPLPPCTPTPSCAEMREDNARVYENVGLMQQQKSFR
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaacatcactggcgtggaggcagaaaacctgctg
ttgacaagaggagttgatggcagttttttggcgaggcccagtaaaagtaaccctggagac
ttcaccctttctgtcagaagaaatggagctgtcacccacatcaagattcagaacaccggt
gattactatgacctgtacggaggggagaagtttgccactctggctgagctggtccagtat
tacatggaacaccacgggcaattaaaagagaagaatggagatgttattgagctcaaatat
cctttgaactgtgcagaccctacctctgaaaggtggtttcatggacacctctctgggaaa
gaagcagagaaattattaacggagaaaggaaaacacggcagctttctggtacgagagagc
cagagccatcctggagattttgttctctctgtccgaactggtgatgacaaaggggaaagc
aacgatggcaagtctaaagtgacccacgttatgatccgctgtcaggaactgaaatatgat
gttggtggaggagaacggtttgactctttgacagatctcgtggagcattacaagaagaac
cccatggtggaaacattgggcacagtgctacaactcaagcagcccctcaacacaacacgc
atcaatgctgctgaaatagaaagccgggttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacagcaacaggaatgcaaa
cttctctacagcagaaaagagggtcagagacaagaaaataagaacaaaaatagatataaa
aacatcctacccttcgatcataccagagttgtcctccatgatggtgatcccaatgagcct
gtttcagattacatcaatgcaaatattatcatgcctgagtttgaaaccaaatgcaacaat
tcaaagcccaaaaagagttacattgccacacaaggctgcctgcaaaacacggtgaatgac
ttctggcggatggtgtttcaagaaaactcacgagtgattgtcatgacgacgaaagaagtg
gagagaggaaagagtaaatgtgtcaaatactggcctgacgagtgtgctctaaaagaatat
ggggtcatgcgtgttaggaacgtcaaagaaagcgccgctcatgactatacgttaagagaa
cttaaactttcgaaggttggacaagctctactccaggggaatacagagagaaccgtgtgg
caataccactttcggacctggccggaccacggagtgcccagtgaccccgggggcgtgcta
gacttcctggaggaggtccaccataagcaagagagcattatggacgcggggcctgtggta
gttcactgcagtgctggaattggccggacagggacgttcattgtgattgatatccttatt
gacatcatcagagagaaaggtgtcgactgcgacatcgatgttcccaagaccattcagatg
gtgcggtctcagaggtcagggatggtccagacggaagctcagtaccgcttcatctacatg
gccgttcagcattacattgaaacactacagcgcaggattgaagaagagcagaaaagcaag
aggaaagggcacgaatatacaaatattaagtattctctcacggaccagacaagtggagat
cagagtcccctcccgccttgtactccaacaccatcctgcgcagaaatgagagaagataat
gccagagtctatgaaaacgtaggtctgatgcagcagcagaaaagtttcagatga
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