Prionailurus bengalensis (leopard cat): 122470345
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Entry
122470345 CDS
T07574
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00061
Fatty acid biosynthesis
pbg00620
Pyruvate metabolism
pbg00640
Propanoate metabolism
pbg01100
Metabolic pathways
pbg04152
AMPK signaling pathway
pbg04910
Insulin signaling pathway
pbg04920
Adipocytokine signaling pathway
pbg04922
Glucagon signaling pathway
pbg04931
Insulin resistance
pbg04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
122470345 (ACACB)
00640 Propanoate metabolism
122470345 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
122470345 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
122470345 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
122470345 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
122470345 (ACACB)
04922 Glucagon signaling pathway
122470345 (ACACB)
04920 Adipocytokine signaling pathway
122470345 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
122470345 (ACACB)
04931 Insulin resistance
122470345 (ACACB)
Enzymes [BR:
pbg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
122470345 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
122470345 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
122470345 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
122470345
NCBI-ProteinID:
XP_043413772
LinkDB
All DBs
Position
D3:18097698..18208248
Genome browser
AA seq
2456 aa
AA seq
DB search
MTLLLFLSCLIFSCLTFSWLKFWGEMTDSKQVTKSTPEGSCSPSQAPFPASDSSGEPPQK
NDNNGPLPETPKRAEPASHRGADDTDQQRTSGPPPRQNPPGDSLSSDDTSPAPQANATGT
ADLKTPDTDGPSSPAKPQGPRARPLSKKDEKQEHIKRQLMTNFILGSFDDNSSDEDPSAG
LFRESPRKGSRASLGTLSLEAALTAGEPENPVPTIRPSMSGLHLVKKGRELKKVDLHRDF
TVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPE
DLKANAEYIKMADQYVPVPGGPNNNNYANVELVVDIAKRIPVQAVWAGWGHASENPKLPE
LLCKHEIAFLGPPSEAMWALGDKIASTIVAQTLQVPTLPWSGSGLMIEWAEDNLQEGKRI
SVPEDIYDQGCVKDVDEGLEVAEKIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQS
EIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPA
VFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPA
AQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGF
KPSSGTVQELNFRSNKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALK
ELSIRGDFRTTVEYLINLLETERFQNNDIDTGWLDHLIAEKVQAEKPDIMLGVVCGALNV
ADVMFRTCMTDFLHSLERGQVLPAASLLNIVDVELIYDGVKYILKVARQSLTMFVLIMNG
CHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRVTIGNKTCVFEKENDPTVLRSPSA
GKLIQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRAGAVLEAGCVVAKLE
LDDPSKVRPAEPFTGELPSQQTLPIIGEKLHQVFHNVLENLTNVMNGYCLPEPIFSTKLK
EWVQKLMTTLRHPSLPLLELQEIMTSVSGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQ
QIASILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRRYLRVEH
HFQQAHYDKCVINLREQLKPNMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEEL
TSILNELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPED
LKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVE
FQFMLPSSHPNRMAVPISVTNPDLLRHSTELFMDSGFAPLCQRMGAMVAFRRFEDFTRNF
DEVISCFANVPREIPLFRKACTPLYSEEENKSLREEPIHILNVAIQYADHLEDEELVPIF
RTFVQSKKNILVEYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLEL
SRMRSFDLTAVPCANHKMHLYLGAAKVKEGAEVTDHRFFIRAIIRHSDLITKEASFEYLQ
NEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRSMVMRYGSRL
WKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDPRSGNIMFHSFGN
KQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALLKLWGSTDKYPKDI
LTYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMRFKTREYPEGRDAIVISNDITFRIGSF
GLGEDLLYLRASEMARAEGIPKIYLAANSGACIGLAEEIKHMFQVAWVDPGDPHKGFKYL
YLTPQDYTRISSLNSVRCKHIEEEGESRYVITDIIGKDRGLGVENLKGSGMIAGESSLAY
EEIVTISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGG
VQIMHHNGVSHVTVPDDFEGVYTILEWLSYMPKDNRSPVPITTPSDPIDREIGFFPSRAP
YDPRWLLAGRPHPTLKGSWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETR
TVEVVVPADPANLDSEAQIIQQAGQVWFPDSAYKTAQAINDFNREGLPLIIFANWRGFSG
GMKDMYDQVLKFGAYIVDSFRQYKQPILIYIPPHGELRGGSWVAVDSSINPLRIETYADK
ESRASILEPEGTVEIKFRKKDLIKTMRRIDPVYKKLVEQLGVSELSDKDRKDLEGQLKAR
EDLLLPIYHQVAVLFADLHDRAHGLLEKGVVSEIVEWKTSRAFLYWRLRRLLLEDQVKQE
ILQASSELSHVHIQSMLRRWFVETEGAVKAYLWDNNQMVVKWLEQHWQGGGGLRSTIREN
IKCLKRDSVLKTIRRLVQDNPEVAADCIVYLSQHISSAERAEVIHLLSTMDSPAST
NT seq
7371 nt
NT seq
+upstream
nt +downstream
nt
atgaccttgcttcttttcctatcttgtttgattttctcctgcttgaccttctcctggtta
aaattctggggggaaatgacagactccaagcaagtcaccaagagcacacccgaagggagc
tgtagcccaagccaagcgccttttccagcctcagacagctcaggggagccgccgcagaaa
aatgataacaacggccctctgccagagactcctaagcgggctgagccagcctcccacaga
ggtgccgacgataccgatcagcaaagaacttccgggccacccccacgccagaatccccca
ggagactccctttcctctgatgacacctccccagcgccccaagccaatgcaacagggacc
gcagacctgaagaccccagataccgatggcccgtcgtctccagccaagccccagggcccg
cgagccagacccctctccaagaaagacgagaagcaggagcacatcaagaggcagctgatg
accaactttatcctgggctccttcgacgacaactcctctgatgaggaccccagtgccggc
ttgttccgagagtctccccggaagggcagccgggccagcctggggactctgtctctggag
gctgctctcactgcaggcgagccggagaaccccgtccccaccataagacccagcatgtcc
ggactccacctggtgaagaagggccgagaactaaagaaggtggacctgcaccgagacttt
accgtggcctccccggctgagtttgtcacgcgcttcgggggggatcgggtcattgagaag
gtgctcatcgccaacaacggcatcgccgccgtgaagtgcatgcgctccatccgcaggtgg
gcctatgagatgttccgcaacgagcgggccatccggtttgttgtcatggtgaccccagag
gacctgaaggccaatgcagagtatatcaagatggcagatcagtacgtccctgtcccagga
gggcccaacaacaacaactatgccaacgtggagctggttgtggacattgccaagaggatc
cccgtgcaggcggtgtgggccggctggggccatgcttccgaaaaccccaaactcccggag
ctcctgtgcaagcatgagattgctttcttaggccctcccagtgaggccatgtgggccttg
ggagataagatcgcctccaccattgtggcccagacgctgcaggtcccaacactgccttgg
agcggaagtggtctgatgatagagtgggcagaagataatctgcaggaggggaaaaggatc
agtgtcccagaagacatttacgaccagggttgtgtgaaagatgtggatgagggcctagag
gtggcagagaaaattggttttcccttgatgatcaaagcttctgaaggcggtggagggaaa
ggaatccggaaagcagagagtgctgaggacttcccaatccttttcagacaagtgcagagt
gagatcccgggctccccgatctttctcatgaagctggcccagcacgcccggcacctggag
gtccagatcctcgccgaccagtacgggaacgctgtgtctctgttcgggcgtgactgctcc
atccagcggcggcatcagaagatcatcgaggaggcaccggctaccatcgccacaccggct
gtgttcgagttcatggagcagtgtgccgtccgcctggccaagaccgtgggctacgtgagc
gcggggacggtggaatacctctacagccaggatggcagcttccactttctggagctgaat
ccccgcctgcaggtggagcacccgtgcacggaaatgatcgccgacgtcaacctgccggcc
gcccagctacagatcgccatgggggtgccgttgcaccggctgaaggatatccggcttctg
tacggagagtcaccatggggggtgacacccatttcatttgaaactccttctaaccctccg
ctcgcccgaggccatgtcatcgcggccagaatcaccagcgagaacccagatgaggggttt
aagccaagctccggaacggttcaggaactgaatttccgcagcaacaagaatgtgtggggt
tatttcagcgtggctgctactggcggcttacacgaatttgcggattcccagttcgggcac
tgcttctcctggggagagaaccgggaagaggccatttcgaacatggtggtggctttgaag
gagctgtccatccggggcgacttcaggaccaccgtggagtatctcattaacctgctggag
accgagcgtttccagaacaatgacatcgacacagggtggttggatcacctcatcgctgag
aaagtgcaggctgagaagccagatatcatgcttggggtggtgtgtggagccttgaacgtg
gccgatgtgatgttcagaacctgcatgacggatttcttacactcgctggaaaggggccag
gtccttcctgccgcttctctgctgaacatcgtggatgtggaattaatttatgatggtgtt
aagtacattctcaaggtggcccggcaatctctgaccatgttcgtcctcatcatgaacggc
tgtcacatcgagatcgacgcccaccggctgaatgacggcgggttactgctgtcctacaat
ggcaacagctataccacctacatgaaagaagaggttgacagttaccgtgttaccattggc
aacaagacctgtgtgtttgagaaggagaacgatcccacggtcctgaggtccccttcggcc
gggaagctaatccagtacacggtggaggacgggggccacgtcgaggctgggagcagctac
gcggagatggaggtgatgaagatgatcatgaccctgaacgtgcaggaaagcggccgggtg
aagtacatcaagcgcgcgggggccgtgctggaagcgggctgtgtggtggccaagctggag
ctcgatgacccttccaaagtgcgcccggccgagccattcacaggagagctcccttcccag
caaactctgcccatcatcggagagaaactacaccaggttttccacaacgtcctggaaaac
ctgaccaacgtcatgaacggctactgtctgccagagcctatttttagcacaaagctgaag
gagtgggtgcagaaactcatgacgaccctgcggcacccgtccctgccgctgctggagctg
caggagatcatgaccagcgtgtcgggccgcatccccgcccccgtggagaagtcggtccgc
agggtgatggctcagtatgccagcaacatcacctcggtgctgtgccagttccccagccag
cagatagccagtatcctggactgccacgcggccaccctgcagcggaaagctgaccgggag
gtgttcttcatgaacacccagagcatcgtgcagctggtccagaggtaccgcagcgggacc
cgcggctacatgaaggcagtggtgttggatctcctgagaagatatttacgcgtggaacac
catttccaacaagctcactacgacaagtgtgtgatcaacctcagggagcagctgaagcca
aacatgtcccaggtgctggactgcatcttttcccacgcgcaggtggccaagaagaaccag
ctggtgatcatgttgatcgatgagctctgtggcccagacccttccctgtcggaagagctg
acctccatcctcaacgagctcactcagctgagcaaaagcgagcattgcaaagtggccctc
agagcgagacaggtcctgatcgcctcccacctcccgtcctacgagctgaggcacaaccag
gtggagtccattttcctgtccgccatcgacatgtatggccaccagttctgcccggaagac
ctcaagaaattaatactgtcagagacgaccatattcgacgtcctgcccactttcttctac
cacgctaacaaggtcgtttgcatggcgtccctggaggtttacgtgcgaaggggctacatc
gcctatgagttaaacagcttgcagcaccggcagctcccagatggcacctgcgtggtagaa
ttccagttcatgctgccctcctcccacccaaaccggatggccgtgcccatcagtgtcacc
aaccccgacctgctgaggcacagcaccgagctcttcatggacagcggctttgccccactg
tgtcagcggatgggggccatggttgccttcaggagatttgaggacttcacaagaaacttc
gacgaagtcatctcctgctttgccaacgtgcccagggaaatccccctcttcaggaaggcc
tgcactcccttgtactctgaagaagagaacaagagcctcagagaggagccaatccacatc
ctgaatgtggccatccagtacgcggaccacctggaagatgaggagctggtgccgattttc
cggacgttcgtacagtccaagaaaaacatccttgtggaatatggactccgaagaatcaca
ttcctgattgcccaagagaaagaatttccgaagtttttcacattcagagcaagagatgag
tttgcagaagatcgcatttaccgtcacctggaacccgccctggccttccagctggagctc
agccggatgcgcagcttcgatctgaccgccgtgccctgcgccaaccacaagatgcacctg
tacctgggcgccgccaaagtgaaagaaggcgcggaggtgacagaccacagattcttcatc
cgcgccatcatcaggcactcggacctcattacgaaggaagcctcctttgagtacctgcag
aacgagggtgagcgtctgctcctggaagccatggatgagctggaggtggcgttcaacaac
accagtgtgcgcaccgactgcaaccacatcttcctgaacttcgtgcccaccgtcatcatg
gaccccttcaagatcgaggagtccgtgcgttccatggttatgcgctacggcagccggctg
tggaaactccgcgtgctgcaggctgaggtcaagatcaacatccgccagaccaccaccggg
agtgctgttcccatccgcctgttcatcaccaacgaatcgggctactacctggacatcagc
ctctacaaagaagtcaccgaccccagatctggaaacatcatgtttcactcctttggcaac
aaacagggcccccagcacgggatgctgatcaacactccctacgtcaccaaggatctgctt
caggccaagcgattccaggcccagtccctgggcaccacctacgtgtatgacttcccagag
atgttcaggcaggctctccttaaactgtggggctccacggacaagtaccccaaagacatc
ctgacatacactgagctcgtgctggaccctcagggccagctggtggagatgaaccgcctc
cctggaggaaatgaggtgggcatggtggccttcaagatgaggtttaagacccgagagtat
ccagaagggcgggacgcgatcgtcatcagcaatgacatcaccttccgcattggatccttc
ggcctgggagaagaccttttgtatctgcgtgcgtctgagatggcccgggcagagggtatc
cccaaaatctacctcgcagccaacagcggggcctgtatcggccttgcagaggagatcaag
cacatgttccaggtggcttgggtggacccaggagacccccacaaaggatttaaatacctg
tacctgacacctcaagactacaccagaatcagctccctaaactctgtccgttgtaaacac
atcgaggaagagggagagtccaggtatgtcatcacggatatcatcgggaaggaccgtggc
ctgggtgtggagaacctcaagggctcgggcatgattgcaggggagtcctccctagcttac
gaagagatcgtcaccatcagtatggtgacctgccgagcccttgggatcggggcctacttg
gtgaggctgggccagcgagtgatccaggtggaaaattcgcacatcatcctgacgggagcc
agcgctctcaacaaggtcctgggcagagaggtttacacctccaacaaccagctgggcggc
gtgcagatcatgcatcacaacggtgtctcccacgtcactgtgccagacgacttcgagggc
gtgtacaccatcctggagtggctgtcctatatgccaaaggataatcgcagtccagtcccc
atcaccacaccctcggaccccattgaccgagaaattggattcttcccgtccagggctccc
tacgacccccggtggctgcttgcaggacggcctcacccaactctgaagggatcctggcag
agtggattctttgaccacggcagtttcaaggaaatcatggcaccttgggcccagacggtg
gtgacaggaagagcgaggctaggggggatccctgttggagtgatcgccgtggagacgcgg
accgtggaggtggtagtgcctgcagaccctgccaacctggattccgaggcccagataatc
cagcaggcgggccaggtgtggttcccagactcagcctacaagacggcccaggccatcaac
gatttcaaccgagagggattgcccctgataatctttgccaactggagggggttctccggt
ggcatgaaagacatgtacgaccaggtgctaaagtttggagcctacatcgtggacagcttc
aggcagtacaaacagcccatcctgatctatatcccaccccacggggaactccgggggggc
tcctgggtggccgtggactcctccatcaaccccctgcgcatagaaacgtacgcagacaag
gagagcagggcgagcattctggagccggagggaacagtggagattaagttccgaaagaaa
gatctgataaagaccatgaggaggatcgacccagtttataagaagctcgtggaacagcta
ggagtgtccgagctctccgataaggaccgcaaggacctggagggccagctgaaggcccgg
gaggacctgctcctgcccatctaccaccaggtggcggtgctgttcgccgacctccacgac
agggcccacggcttgctggagaagggtgtcgtctctgaaatcgtggagtggaagacctca
cgcgccttcctgtactggcgtctgcgccgcctcctgctggaggaccaggtcaagcaggag
atcctgcaggccagcagtgagctgagccacgtgcacatccagtccatgctgcgtcggtgg
ttcgtggagacggagggggccgtcaaggcctacctgtgggataacaaccagatggtggta
aagtggctggaacagcactggcagggcgggggcggcctgcgttccaccatccgcgagaac
atcaagtgtttgaagcgcgactccgtcctcaagaccatcagacgcctggttcaagacaac
cctgaggtggccgcggactgcatcgtgtacctgagccagcacattagctcagcagagcgg
gccgaagtcattcacctcctgtccaccatggacagcccagcctccacctga
DBGET
integrated database retrieval system
