Prionailurus bengalensis (leopard cat): 122473119
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Entry
122473119 CDS
T07574
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg04010
MAPK signaling pathway
pbg04020
Calcium signaling pathway
pbg04022
cGMP-PKG signaling pathway
pbg04024
cAMP signaling pathway
pbg04260
Cardiac muscle contraction
pbg04261
Adrenergic signaling in cardiomyocytes
pbg04270
Vascular smooth muscle contraction
pbg04713
Circadian entrainment
pbg04720
Long-term potentiation
pbg04723
Retrograde endocannabinoid signaling
pbg04724
Glutamatergic synapse
pbg04725
Cholinergic synapse
pbg04726
Serotonergic synapse
pbg04727
GABAergic synapse
pbg04728
Dopaminergic synapse
pbg04742
Taste transduction
pbg04911
Insulin secretion
pbg04912
GnRH signaling pathway
pbg04921
Oxytocin signaling pathway
pbg04924
Renin secretion
pbg04925
Aldosterone synthesis and secretion
pbg04927
Cortisol synthesis and secretion
pbg04929
GnRH secretion
pbg04930
Type II diabetes mellitus
pbg04934
Cushing syndrome
pbg04935
Growth hormone synthesis, secretion and action
pbg05010
Alzheimer disease
pbg05020
Prion disease
pbg05022
Pathways of neurodegeneration - multiple diseases
pbg05031
Amphetamine addiction
pbg05207
Chemical carcinogenesis - receptor activation
pbg05410
Hypertrophic cardiomyopathy
pbg05412
Arrhythmogenic right ventricular cardiomyopathy
pbg05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122473119 (CACNA1C)
04020 Calcium signaling pathway
122473119 (CACNA1C)
04024 cAMP signaling pathway
122473119 (CACNA1C)
04022 cGMP-PKG signaling pathway
122473119 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
122473119 (CACNA1C)
04929 GnRH secretion
122473119 (CACNA1C)
04912 GnRH signaling pathway
122473119 (CACNA1C)
04921 Oxytocin signaling pathway
122473119 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
122473119 (CACNA1C)
04924 Renin secretion
122473119 (CACNA1C)
04925 Aldosterone synthesis and secretion
122473119 (CACNA1C)
04927 Cortisol synthesis and secretion
122473119 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
122473119 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
122473119 (CACNA1C)
04270 Vascular smooth muscle contraction
122473119 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
122473119 (CACNA1C)
04727 GABAergic synapse
122473119 (CACNA1C)
04725 Cholinergic synapse
122473119 (CACNA1C)
04728 Dopaminergic synapse
122473119 (CACNA1C)
04726 Serotonergic synapse
122473119 (CACNA1C)
04720 Long-term potentiation
122473119 (CACNA1C)
04723 Retrograde endocannabinoid signaling
122473119 (CACNA1C)
09157 Sensory system
04742 Taste transduction
122473119 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
122473119 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
122473119 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
122473119 (CACNA1C)
05020 Prion disease
122473119 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
122473119 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
122473119 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
122473119 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
122473119 (CACNA1C)
05414 Dilated cardiomyopathy
122473119 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
122473119 (CACNA1C)
04934 Cushing syndrome
122473119 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pbg04040
]
122473119 (CACNA1C)
Ion channels [BR:
pbg04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
122473119 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
CAC1F_C
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
122473119
NCBI-ProteinID:
XP_043419202
LinkDB
All DBs
Position
B4:complement(35069483..35830031)
Genome browser
AA seq
2196 aa
AA seq
DB search
MVNENTRMYIPEENHQGSNYGSPRAAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTISSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
TMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGD
FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNRSTPAGLLDQKKGKFAW
FSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRR
KCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKM
YSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWN
SLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQS
LLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDN
LADAESLTSAQKEEEEEKERKKLARPARTASPEKKQEIMEKPAVEETKEEKIELKSITAD
GESPPTTKINMDDLQPNENEDKSPYPNPENTGEDDEEEPEMPVGPRPRPLSELHLKEKAV
PMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHI
LGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAIN
VVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFK
GKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVS
TFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQ
GEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLN
TICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVI
GSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPFMNAEENSRIS
ITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGK
IALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGE
TPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEY
DPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFA
LVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLI
QEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMK
EAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGNSQGDTESPS
HEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPRPAGYPSAVSTVEGHGPPLSPAVRV
QEAAWKLSSKRCHSRESQIAMVCQEEVSQDETYDVKISEDTEYCSEPSLISTEMLSYQDD
ENRQLTPPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKNQGGDISQKTVLPLHL
VHHQALAVAGLSPLLQRSHSPSTSPRPCATPPATPGSRGWPPQPIPTLRLEGAESNEKLN
SSFPSIHCSSWSGEPTPCGGGGSTIRRARPVSLTVPGQAGAQGRQFHGSASSLVEAVLIS
EGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDP
GQDRAEGQEGETCAPTLACRKSEEELQDSRAHVGSL
NT seq
6591 nt
NT seq
+upstream
nt +downstream
nt
atggtcaatgagaacacgaggatgtacattccagaggaaaaccaccaaggttccaactat
gggagcccgcgtgcagctcacgccaacatgaatgccaatgcggctgcggggctcgccccc
gagcacatcccaacgcccggggcagccttgtcctggcaggcagccatcgacgcggcccgg
caggctaagctgatgggcagcgctggcaatgcaaccatctccaccatcagctccacacag
cggaagcggcagcaatatgggaaacccaagaagcagggcagcacgactgccacacgcccg
ccccgtgccctgctctgcctgactctgaagaaccccatcaggagggcgtgcatcagcatc
gtcgaatggaaaccatttgaaataattattttactgactatttttgccaattgtgtggcc
ttagcgatctatattccctttccagaagatgactccaatgccaccaattccaacctggaa
cgagtggaatatctctttctcataatttttactgtggaagcatttttaaaagtaatagcc
tatggacttctctttcaccccaacgcttacctccgcaatggctggaatttactagatttt
ataattgtggttgtagggctttttagtgcaattttagaacaagccaccaaagctgacggg
gcaaatgctctaggaggtaaaggagctggatttgatgtgaaggcactgagggcattccgc
gtgctgcgccccttgcggctggtgtctggagtcccaagtctccaagtcgttctgaattcc
attatcaaggccatggtccccctgctgcatattgccctgttagtgctatttgtcatcatc
atctacgctatcattggcctggagctcttcatgggaaagatgcataagacctgctacaac
caggagggcatagcagatgttccagcagaagatgatccttccccttgtgctctggagact
ggccatgggcggcagtgccagaatggcactgtgtgcaagcctggctgggacgggcccaag
cacggcatcaccaactttgacaattttgccttcgccatgttgacagtgttccagtgcatc
accatggagggctggacagatgtgctatactggatgcaggacgctatgggctatgagtta
ccctgggtgtattttgtcagtctggtcatctttggatcctttttcgttctaaatctggtt
ctcggtgtgttgagcggagagttttccaaagagagagagaaggccaaggctcggggagac
ttccagaagctgcgagagaagcagcagctggaagaggacctgaagggctacctggactgg
atcacccaggcagaggacatcgaccctgagaacgaggacgaaggcatggatgaggagaag
ccccgaaacagaagcactccagcgggcttgcttgatcagaagaaagggaagtttgcttgg
tttagtcactccacagaaacccatgtgagcatgcccacaagtgagaccgagtctgtcaac
accgaaaacgtggctggaggtgacatcgagggagagaactgcggggccaggctggcccat
cggatttccaaatcaaagttcagccgctactggcgtcggtggaatcggttctgcagaaga
aagtgtcgtgctgcagtcaagtctaatgtcttctactggcttgtgatcttcctggtgttc
ctcaacacactcaccatcgcctcagaacattacaaccagccccactggctcacggaagtc
caagacacggccaacaaggcactactggcccttttcactgcggagatgctgctaaagatg
tacagcctgggcctgcaggcctactttgtgtccctcttcaaccgctttgactgcttcatc
gtgtgtgggggcattctggagaccatcctggtggagaccaagatcatgtctcccttgggc
atctctgtgctgagatgtgtccggctactgcggatatttaaaatcacaaggtactggaac
tccttaagcaacctggtggcatccttgctgaattctgtgcgctccattgcctccctgctg
ctactcctcttcctcttcatcatcatcttctccctcctggggatgcagctctttggagga
aagttcaactttgatgagatgcagactcggaggagcacatttgataactttcctcagtcc
ctcctcaccgtgtttcagatcctgaccggggaggactggaattcggtgatgtatgatggg
atcatggcttatggcggcccctcttttccagggatgttagtctgtatttacttcatcatc
ctcttcatctgtggaaactatatcctactgaatgtgttcttggccattgctgtggacaac
ctggctgatgctgagagcctcacatctgcccaaaaggaggaggaagaagagaaggagaga
aagaagctggccagaccggccaggactgccagcccagagaagaagcaagagataatggaa
aagccagctgtggaggaaaccaaggaggagaaaattgagctgaaatccattacagctgat
ggagagtccccacccaccaccaagatcaacatggatgacctccagcccaatgaaaatgaa
gataagagtccctaccccaacccagaaaatacaggagaagacgatgaagaggagcctgag
atgcctgtgggcccccgcccacgaccactctctgagctgcaccttaaggaaaaggcagtg
cccatgccagaagccagtgcatttttcatcttcagccccaacaacagatttcgcctccag
tgccaccgcattgtcaatgacacgatcttcaccaacctgatcctcttcttcattctgctc
agcagcatttccctggcagctgaggaccctgtccagcacacctccttcaggaaccatatc
ctaggcaatgcagactatgtcttcactagtatctttacattagaaattatccttaagatg
actgcttatggggctttcctacacaagggctctttctgccggaactacttcaacatcttg
gatctgctggtggtcagcgtgtccctcatctcctttggcatccagtccagtgcaattaat
gtggtgaagatcttgcgagttctgcgagtcctcaggcccctgagggccatcaacagggcc
aaggggctaaagcacgtggtccagtgcgtgtttgtcgccatccgaaccatagggaatatc
gtgattgtcaccacgctgctccagttcatgttcgcctgcatcggggtccagcttttcaag
ggaaagctctacacctgttcagatagttccaagcagaccgaggcggaatgcaagggtaac
tacatcacatacaaggatggggaagttgaccaccccatcatccagcctcgcagctgggaa
aacagcaagtttgactttgacaatgttctggcagccatgatggccctctttaccgtctcc
acctttgaggggtggccagagctgctgtaccgctccatcgactcccacacagaagacaag
ggccccatctacaactaccgtgtggagatctccatctttttcatcatctacatcatcatc
attgccttcttcatgatgaacatcttcgtgggttttgtcatcgtcaccttccaggagcag
ggggagcaggaatacaagaactgtgaactggacaagaaccagcgacagtgtgtggaatat
gccctcaaggcccggcccctgcggaggtacatccccaaaaaccagcaccagtacaaagtg
tggtacgtggtcaactccacctactttgaatacctgatgttcgtcctcatcctgctcaac
accatctgcttggcaatgcagcactatggccagagctgcctattcaaaatcgccatgaac
atcctcaacatgctcttcactggcctcttcactgtggagatgattctgaagctcattgcc
ttcaaacccaagggttactttagtgatccctggaatgtttttgacttcctcatcgtaatt
ggcagcataattgacgtcattctcagtgaaactaatcactatttctgtgatgcatggaat
acatttgacgccttgattgttgtgggtagcattgttgatatagcaatcaccgaggtaaac
ccagctgaacatacccaatgctctccctttatgaacgcagaggagaactcccgcatctcc
atcaccttcttccgcctcttccgggtcatgcgactggtcaagctgctaagccgtggggag
ggcatccggaccctgctgtggaccttcatcaagtctttccaggctttgccctatgtggcc
cttctgatagtgatgctgttcttcatctacgcagtgatcgggatgcaggtgtttgggaaa
attgccctgaatgacaccacagagatcaaccggaacaacaactttcagaccttcccccaa
gctgtgctccttctcttcaggtgtgccacaggggaggcatggcaagatatcatgctggcc
tgcatgccagggaagaagtgtgcccccgagtcagagcccagcaacagcacggaaggggaa
acgccctgtggcagcagttttgccgtcttctacttcatcagcttctacatgctctgtgcc
ttcctgatcatcaacctctttgtagctgtcatcatggacaactttgactacctgacaaga
gactggtcaatccttggtccccatcatctggatgaatttaaaagaatctgggcagagtat
gatcctgaagctaagggtcgtatcaaacacctagatgtggtgaccctgctccggcggatt
cagcccccactgggttttgggaagctgtgccctcaccgcgtggcttgcaaacgcctggtc
tccatgaacatgcctctgaacagtgatgggactgtcatgttcaatgccaccctgtttgcc
ctagtccggacagccctgcggatcaaaacagaagggaacctagaacaagccaatgaggag
ctgcgggccataatcaagaagatctggaagcgtaccagcatgaagctgctagaccaagtg
gtgccccctgcaggtgatgatgaggtcaccgttggcaagttttatgctactttcctgatc
caagagtacttccggaaattcaagaagcgcaaagagcagggccttgtgggcaagccttcc
caaaggaacgccctgtccttgcaggctggcttgcgcacgctgcatgacattgggcctgag
atccgacgggccatctctggagatctgacagctgaggaggagctggacaaggccatgaag
gaggctgtgtctgctgcctccgaagatgacatcttcaggagggccggtggcctgttcggc
aaccacgtcagctactaccaaagcgacggccggagcgccttcccccagaccttcaccacc
cagcgcccactgcacatcaacaaggcgggtaacagccaaggcgacaccgagtcgccatcc
cacgagaaactggtggactccaccttcacccccagcagctactcgtccactggctccaac
gccaacatcaacaatgccaacaacactgccctgggccgcttcccccgtcccgctggctac
cccagcgcagtcagcaccgtggagggccatgggccccccttgtctcctgctgtccgggtt
caggaggcagcatggaagctcagctccaagaggtgccactcccgggagagccagatagcc
atggtgtgtcaggaagaggtctctcaggacgagacctatgacgtgaagataagtgaagac
actgagtactgcagcgagcccagcctgatctccacagagatgctctcctatcaggatgat
gaaaatcggcaattaacaccaccggaggaggacaagagagatatccggcaatctccaaag
aggggcttcctccgctctgcctcactaggtcgaagggcctccttccacctggaatgtctg
aagcgacagaagaatcaagggggagacatctctcagaagacagtcctgcccttgcatctg
gttcatcatcaggcattggcggtggcaggcctgagccccctcctccagagaagccattcc
cccagcacatcccccaggccctgtgccaccccaccagccactccaggcagccgaggctgg
cccccacagcctatccccaccctgcggctggagggtgccgaatccaacgagaaactcaac
agcagcttcccgtccatccactgcagctcctggtctggggagcccacaccctgtggtgga
ggtggcagcaccatccggagagcccggccagtgtccctcactgtgcccggccaggctggg
gcccagggcaggcagttccacggcagtgccagcagcctggtagaagcggtcttgatttca
gaaggactggggcagtttgctcaagatcccaagtttattgaggtcacaacccaggagctg
gctgacgcctgtgacatgaccatagaggagatggagaacgccgcagacaacatcctcagt
gggggcgcccagcagagccccaatggcaccctactacctttcgttaactgcagggaccca
gggcaggacagagcagagggccaagagggcgagacctgcgcgcccaccctggcgtgtcgg
aagagcgaggaagagctccaggacagcagagcccacgtcggcagcctgtag
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integrated database retrieval system
