Prionailurus bengalensis (leopard cat): 122476530
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Entry
122476530 CDS
T07574
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00140
Steroid hormone biosynthesis
pbg00980
Metabolism of xenobiotics by cytochrome P450
pbg01100
Metabolic pathways
pbg05204
Chemical carcinogenesis - DNA adducts
Module
pbg_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
122476530 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
122476530 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
122476530 (HSD11B1)
Enzymes [BR:
pbg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
122476530 (HSD11B1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
Shikimate_DH
DUF1776
NAD_binding_2
2-Hacid_dh_C
NAT10_TcmA_helicase
ADH_zinc_N
Motif
Other DBs
NCBI-GeneID:
122476530
NCBI-ProteinID:
XP_043425272
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All DBs
Position
E4:complement(33042193..33092569)
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AA seq
292 aa
AA seq
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MAFMKKYLPPILGIFLAYYYYSANEEFRPEMLQGKKVIVTGASKGIGEQMAYHLAKMGAH
VVVTARSKENLKKIVSHCLELGAASAHYIAGTMENMTFAEQFVAKAGKLMGGLDMLILNH
ITNTSMNLFSGDIHIVRRSMEVNFLSYVVLSATALPMLKQSNGSIVVVSSKAGKMASPLI
APYSASKFALDGFFSSIRMEHSVAKINVSITLCILGLINTDTAMNAISGIVNMEASPKEE
CALEIIKGGALRQEEVYYDNSVWTALLLGNPGRKILELFSLRSYSLDKFIIN
NT seq
879 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaaatatctcccccccattctggggatcttcttggcctactactac
tattctgcgaatgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaggggattggagaacagatggcctatcatctggcaaagatgggggcccat
gtggtggtgacagcaaggtctaaagaaaatctaaagaagatagtatcccattgcctggag
cttggagcagcctcagcacactacattgctggcaccatggagaatatgaccttcgcagag
caatttgttgccaaagctggaaagctcatggggggactagacatgcttattctcaaccac
atcaccaacacttctatgaatctgtttagtggtgatatccacatcgtgcgcagaagcatg
gaagtcaacttcctcagttatgtggtcctgagtgctactgccttgcctatgctgaagcag
agcaacggaagcattgttgtcgtgtcctcgaaggctgggaaaatggctagtccacttatt
gcgccctattctgcaagcaagtttgccctggatgggtttttctcctccatcaggatggaa
cattcagtggccaagattaatgtatcgatcactctctgtatcctcggcctcataaacaca
gacacagccatgaatgccatttctggaatagtcaacatggaggcatctccaaaggaagaa
tgtgccctggagatcatcaaagggggagctctgcgccaagaggaagtgtactatgacaac
tcagtctggacagctctcctgctgggaaatccagggaggaagattctggaactcttctcc
ttaagaagttatagtttggacaagtttataatcaactaa
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