Prionailurus bengalensis (leopard cat): 122477260 Help Entry 122477260         CDS       T07574                                  Symbol IRS4 Name (RefSeq) insulin receptor substrate 4   KO K17446   insulin receptor substrate 4 Organism pbg  Prionailurus bengalensis (leopard cat) Pathway pbg04022   cGMP-PKG signaling pathway pbg04068   FoxO signaling pathway pbg04081   Hormone signaling pbg04140   Autophagy - animal pbg04152   AMPK signaling pathway pbg04211   Longevity regulating pathway pbg04213   Longevity regulating pathway - multiple species pbg04910   Insulin signaling pathway pbg04920   Adipocytokine signaling pathway pbg04923   Regulation of lipolysis in adipocytes pbg04930   Type II diabetes mellitus pbg04935   Growth hormone synthesis, secretion and action pbg05010   Alzheimer disease Brite KEGG Orthology (KO) [BR:pbg00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     122477260 (IRS4)    04022 cGMP-PKG signaling pathway     122477260 (IRS4)    04152 AMPK signaling pathway     122477260 (IRS4)   09133 Signaling molecules and interaction    04081 Hormone signaling     122477260 (IRS4)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     122477260 (IRS4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     122477260 (IRS4)    04923 Regulation of lipolysis in adipocytes     122477260 (IRS4)    04920 Adipocytokine signaling pathway     122477260 (IRS4)    04935 Growth hormone synthesis, secretion and action     122477260 (IRS4)   09149 Aging    04211 Longevity regulating pathway     122477260 (IRS4)    04213 Longevity regulating pathway - multiple species     122477260 (IRS4)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     122477260 (IRS4)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     122477260 (IRS4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH_11 PH_8 PH Motif Other DBs NCBI-GeneID:  122477260 NCBI-ProteinID:  XP_043426082 LinkDB All DBs Position X:complement(89694944..89712638) Genome browser AA seq 1243 aa AA seqDB search MASCSFARDQATRRLRAAAAATAAALAAVATTPLLSSGTPTALIGTGSSCPGAMWLSTAT GSRSDSESDEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH SVRAAAAAAAAAASGATVPALIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMV AENESEQESWYLLLSRLILESKRRRCGTPGAQPDGEPAALAAAAAAEPPFYKDVWQVIVK PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRH LDTLPLEPSGWLRRSRFEQFCHLRAIGDGEDEMLLTRRYITPSEPVPPSRRGRLHLPRAR RSRRAISVPASFFRPTPSPVRVPHPVEAPNHRACLSSEASRPGNSGEKDSPQGKEDQEGT EGDYMPMNNWGSGNGQGSGGGQGSSGQGSSSQSSGGSQCSGGGQGSGRGQGSSGGQGSSG GQGAGGSQRSGDGHGTAGGHGSGSGQGASGGHGSGSGQGSGDGHGSGGGKNSGGGKGPGG GKTPEGSGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPGATGGKGKSGGRFRLYFCA DRGATKQRKEAKEVKEAETPEGAARGPHRARAFDEDEDDPYVPMRPGVAAPLASSSDYMP MAPQNFSASKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKEPDPDKDDEAKDNDSDSDYM FMAPGAGAIPKNPPNPQGGSSSKSWSSYFSLPNPFQGSPLGQSDHSEYVPMLPGKFLGKG LDKESSSNRGPKDAVSKPSVEGSFSKPGDNSPSKNKAKRPNRLSFITKGNKIKPKSQKPT REQREADSPGDYVNIDFTKRDTNMPAPFIQGLPGSWSIIAGPRPSAFSNYVNVEFRVPFP NPAHSLSNLLRAFPGANPLFLEGARWPFVPLPPSTTGGNANEEEGDYIEVIFNPAMTPAV PFADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEDGLERRRPQSHS QSFFASARAAVSAFPTDSLERDLSASLASVAAPALAVSRALAAASALAAAPGIGAAARGL EAAAGLDSASVRRFQPVASAAAAEAVRGAPDVARGSNPRAPNPDADLARDENGAAAAAPP PPPPRRRVPIPREREDSDDDDDTYVRMDFARPDNKKFDSPHRE NT seq 3732 nt NT seq  +upstreamnt  +downstreamnt atggcgagttgctccttcgctcgcgaccaggcgacaaggaggctgagagctgcagcagcg gcaacagcggcagcgctagctgcggtggcgaccaccccgcttctttcctcgggcaccccg accgcactcattgggaccgggtcgtcttgtccgggagccatgtggctctccacggccact ggctcccggtcagactccgagtcagatgaggaggacctccccgtcggggacgaagtctgc aaacgcggctacctgcggaagcagaagcatggacacaggcgctacttcgtactcaaactc gagaccgcggacgccccagctcggctggaatactacgaaaatgccaggaagttccggcac agtgtccgcgccgcggcggctgcagcggcggcggccgcctccggcgccacggtccccgcg ctcatcccaccgcggcgcgtgatcaccctgtaccagtgcttctcggtgagccagcgggcc gacgcaaggtaccgacacctcatcgccctctttacccaggacgagtacttcgcgatggtg gccgagaacgagtcggagcaagagagctggtacttgctgctcagccgcctcatcctcgag agcaagcgccgccgctgcggcacgcccggcgcgcagccggatggagagccggccgcgctg gcggctgcagcggcggcggagccacccttctacaaagatgtgtggcaggtaatagtcaaa cccagggggctggggcacagaaaagagctgagcggcgtgttccggctctgtcttaccgac gaggaggttgtctttgtgaggttgaacaccgaagtggccagcgtggtcgtccagctcctg agcatccgtcgctgcgggcactcagagcagtatttcttcttggaagtcggtaggtccacc gtcatcggtccgggggaactctggatgcaggtcgatgactgcgtggtggcccaaaacatg cacgagctgtttctggagaagatgagagccctgtgtgcagacgaatacagagcccgctgc cgcagctacagcatcagcatcggcgcccacctgttaaccctgctgtccgctaggaggcac ctggacacgctcccgctggaacccagcggctggctgagaaggtcccgctttgagcagttt tgccacctcagggccattggtgacggggaagacgagatgctcctcaccaggcgctacata acacccagcgagcccgtgcccccctccaggcgaggaagactgcacctgcccagagcgcgc aggtccaggagagcgatttcagtgccagccagcttttttcgcccaacacccagtccggtg cgtgtcccgcatcctgtagaagcccccaaccacagagcttgcctgtcctctgaagcatct cgccctggcaactctggggaaaaagacagtcctcagggcaaagaggatcaggaaggaacc gaaggtgactacatgcccatgaacaactggggctcaggaaatggccagggttctggaggt ggccagggctcaagtggccaaggctccagtagccagagttcaggaggaagccagtgctcg ggtggagggcagggatctggacgtggccagggctcaagtggtggccagggctcaagcggt ggccagggggcaggaggaagccagcgttcaggagatggccacggcactgcgggtgggcac ggttcaggcagtggccagggagccagtggtggacatggctcgggcagtgggcagggatct ggagatggtcatggctcaggtggtggcaagaactctggagggggcaaaggcccaggaggt gggaagacccccgaaggcagtggtgaacgtggaaaatctctgaagaaaagatcctacttt ggcaaattaactcaaagcaagcagcagcaaatgccaccacctccacctccaccccctcca cctggagcaactggtggtaaagggaagtctgggggaaggttccgactctacttttgtgcc gacagaggagccacaaaacaacgcaaagaagccaaagaagtcaaagaggcagagacccca gaaggtgcagctcgggggccccacagagccagagcttttgatgaagacgaagatgaccca tatgtgccaatgaggccaggggtggctgcccctctggcaagctccagcgattatatgccg atggctcctcaaaacttctctgcttcaaaacgccactctcgatcaccttttgaagattca agagggtacatgatgatgtttcccagagtgagcccaccacctgccccaagtcctccaaaa gagcctgatcctgataaggatgacgaggcaaaggacaatgacagtgacagtgactatatg tttatggctcccggagccggtgcaattccaaaaaaccccccaaaccctcagggtggttct tcctctaaaagttggagctcttacttttctctgccaaatccctttcagggctccccattg ggacagagtgaccacagtgagtatgtaccaatgttacctggaaaattcctggggaagggc ctagacaaagaatcctcatctaacaggggccccaaagacgcagtttcaaagccttcagtt gaggggtcattctcaaagcctggagataacagcccctccaagaacaaggctaagagacct aaccgcctttcttttattacaaaaggaaataaaatcaagcccaaatcacaaaaacccaca cgtgaacagagagaagctgacagccctggtgactacgtcaacattgacttcactaagaga gatactaatatgccagccccctttattcaaggactgccaggttcgtggagtatcattgct ggccccagaccatcagccttttctaattatgtgaatgttgagttcagagtgccatttccg aacccagcacacagcctctcgaatctattaagagcttttccaggtgccaaccccctcttt ctggaaggtgctaggtggccatttgtgcctcttcctcccagtactacaggtggtaatgct aatgaggaagagggtgactacattgaagtgattttcaatccagcaatgacaccagccgtg ccttttgctgacagtgccattcgctatgatgctgaaacaggtcgaatctatgtggtcgac ccattttctgagtgctgtatggacatttctctttcccccagccgctgctctgaaccacca cctgtggctaggctgctgcaggaagacgggctggagcgcagacgcccgcagagccattcg caaagtttctttgcctccgctagagctgctgtctcggctttccccaccgacagccttgag agagacctctccgcctccttagcctccgtagctgcgccagccttagccgtgagccgggct ttggccgccgcctccgccctcgccgcggccccgggcatcggtgcggccgccagaggcttg gaggccgccgctggacttgactccgcctccgtccgccggttccaacctgttgctagcgct gctgccgccgaagcggtaaggggggccccagacgttgcccgtggctcgaacccgagggcc ccaaacccagatgcagacctggcccgagatgagaacggggctgcagcggccgccccccca ccgccaccaccccgccgccgggtcccgattccccgggagcgagaggattccgacgacgac gacgacacatacgtgagaatggactttgccagaccggacaacaagaagttcgactctccc cacagagagtga

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