Prionailurus bengalensis (leopard cat): 122484873 Help Entry 122484873         CDS       T07574                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism pbg  Prionailurus bengalensis (leopard cat) Pathway pbg04022   cGMP-PKG signaling pathway pbg04068   FoxO signaling pathway pbg04081   Hormone signaling pbg04140   Autophagy - animal pbg04152   AMPK signaling pathway pbg04211   Longevity regulating pathway pbg04213   Longevity regulating pathway - multiple species pbg04910   Insulin signaling pathway pbg04920   Adipocytokine signaling pathway pbg04923   Regulation of lipolysis in adipocytes pbg04930   Type II diabetes mellitus pbg04931   Insulin resistance pbg04932   Non-alcoholic fatty liver disease pbg04935   Growth hormone synthesis, secretion and action pbg05010   Alzheimer disease pbg05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:pbg00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     122484873 (IRS2)    04022 cGMP-PKG signaling pathway     122484873 (IRS2)    04152 AMPK signaling pathway     122484873 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     122484873 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     122484873 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     122484873 (IRS2)    04923 Regulation of lipolysis in adipocytes     122484873 (IRS2)    04920 Adipocytokine signaling pathway     122484873 (IRS2)    04935 Growth hormone synthesis, secretion and action     122484873 (IRS2)   09149 Aging    04211 Longevity regulating pathway     122484873 (IRS2)    04213 Longevity regulating pathway - multiple species     122484873 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     122484873 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     122484873 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     122484873 (IRS2)    04932 Non-alcoholic fatty liver disease     122484873 (IRS2)    04931 Insulin resistance     122484873 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N TetR_C_6 Motif Other DBs NCBI-GeneID:  122484873 NCBI-ProteinID:  XP_043438867 LinkDB All DBs Position A1:complement(79992615..80025399) Genome browser AA seq 1332 aa AA seqDB search MASPPLHGPPGPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGDEAAAA GGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDEYF AVAAENEQEQEGWYRALTDLVSEGRAGAGDAPPAAAATAASCSASLPGALGGSAGAAAAD DSYGLVAPASAAYREVWQVNLKPKGLGQSRNLTGVYRLCLSARTIGFVKLNCEQPSVTLQ LMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFR PRSKSQSSGSSSTHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRV RTASEGDGGAAAAGAGAAGGRPVSVAGSPLSPGPVRTPLSRSHTLSGGGGGGGGRAGKVA LAPAGGALQHSRSMSMPVAHSPPAATSPSSLSSSSGHGSGSYPPPPGPHPHLQHPLHQPA SQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGGE LYGYMTMDRPLSHCGRPYRRVSGDGAQDVDRGLRKRTYSLTTPARQRPVPQPSSASLDEY TLMRVSFSGSSGRLCPSCPASSPKAAYHPYPEDYGDVEIGSHRSSSSNLGTDDGYMPMTP GAALTGGGSGSCRSDDYMPMSPTSVSAPKQILQPRAAAAALPPAGAPVSTPAASRAFPAS GGSYKASSPAESSPEDSGYMRMWCGSKLSMENADSKLLPNGDYLNMSPSDAGASGTPPDF FSAALHGSGETLRGVPGYCHSSLPRSYKAPYTCNGDNNDQYVLMSSPVGRILEEERLEPL ASPGTAPSSGCGGGGHAQPPHPAVPSPGRPGGSVGGRPEGFLNQRCRAVRPTRLSLEGLQ TLPSMHEYPLPPEPKSPGEYINIDFGDAGARLSPPAPPLLASAASSSSLLSASSPASSLG SGTPGTSGDSRQRSPLSDYMNLDFSSPKSPKPGPQGGDPVGSLDALLSPEASSPYPPLPP RPAASASALQPQPLPPPPPGELYRLPPAPAAQGPSAASSSSSETGDNGDYTEMAFGVAAT PPQPIAAPPKPEGARVTSPTSGLKRLSLRDQVSGVEAFLQASQPPDPHRGAKVIRADPQG GRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGAGGGGLAGGDERPT SPRQLQPPPPQQARPWLPSQPGGLVGCPGGSGSPMRRETSAGFQNGLNYIAIDVRDEPGL SPGPQQLPHPQPGDKSAWGRTRSLGGLLSAVGGGSTGGVCGGPGPGALPSANTYASIDFL SHHLKEATIVKE NT seq 3999 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgctgcacgggccccccgggccggcgggtggcgacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggttacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgacgaggcggcggcggcg ggcggggggccggcgccgcagccgccgcggctcgagtactacgagagcgagaagaagtgg cggagcaaggcgggcgccccgaagcgggtcatcgcgctcgactgctgcctgaacatcaac aagcgcgccgacgccaagcacaagtacctgatcgcgctctacaccaaggacgagtacttc gccgtggcggccgagaacgagcaggagcaggagggctggtaccgcgcgctcaccgacctg gtcagcgagggccgcgcgggcgccggcgacgcgccccccgccgccgccgccaccgccgcg tcctgcagcgcctccctgcccggcgccctgggcggctcggccggcgccgccgcggccgat gacagctacgggctggtggcgcccgcctcggccgcctaccgcgaggtgtggcaggtgaac ctgaagcccaagggcctgggccagagcaggaacctgacgggcgtgtaccgcctgtgcctg tcggcgcgcaccatcggctttgtgaaacttaactgtgagcagccgtcggtgacgctgcag ctcatgaacattcgccgctgcggccactcggacagcttcttcttcatcgaggtgggccgg tcggccgtcacgggcccaggtgagctgtggatgcaggccgacgactcggtggtggcgcag aacatccacgagaccatcttggaggccatgaaggcgctcaaggagctcttcgagttccgg ccgcgcagcaagagccagtcgtcgggctcgtcctccacacaccccatcagcgtccccggc gcgcgccgccaccaccacctggtcaacctgccccccagccagacgggcctggtgcgccgc tcgcgcaccgacagcctggccgccaccccgccggcagccaagtgcagctcgtgccgggtg cgcacggccagcgagggcgacggcggcgcggcggcggcgggggccggggcggcgggcggc aggcccgtgtcggtggccgggagtcccctgagccccgggccggtgcgaacgcccctgagc cgctcacacaccctgagcggcggcggcggcggcggcggcggccgcgcgggcaaggtggcg ctggcgccggcagggggcgccctgcaacacagccgctccatgtccatgcccgtggcgcac tctcccccagcagccaccagccctagcagcctgtcgtccagcagcgggcacggctccggc tcctacccaccgcctccgggcccgcacccgcacctgcagcaccccctgcaccagcccgcg agccagcggccctccagcggcagcgcctcggcctcagggtcccccagcgaccccggcttc atgtctctggacgagtacggctccagccctggggacctgagagccttctgcagccaccgg agcaacacgcccgagtccattgccgagacgcccccggcccgggacggcagcgggggcgag ctgtacgggtacatgaccatggacaggcccctgagccactgtggccgcccctaccgcaga gtctccggggacggggcccaggacgtggacagaggcctgaggaagcggacgtactccctg accacacctgcccggcagcggcccgtgccccagccctcctctgcgtccctggacgaatac accctgatgcgggtctccttctctggcagctccggccgcctctgcccgtcctgccccgcc tcatctcccaaagcggcctaccacccctaccccgaggactacggggacgtcgagatcggc tcccacaggagctccagcagtaacctgggtacggacgacggctacatgcccatgaccccc ggcgcggccctcacggggggtggcagtggcagctgtaggagtgacgactacatgcctatg agccccaccagcgtgtctgccccaaagcagatcctgcagcctcgggctgccgctgcggcc ttgccccccgcgggagcgccggtgtccacacccgcagccagcagggccttcccggccagc gggggcagctacaaggcgagctccccggcggagagctcccccgaggacagcgggtacatg cgtatgtggtgtggctccaagctgtccatggagaacgcagacagcaagctgctgcccaac ggggactacctcaacatgtcccccagcgacgcgggcgcctcggggacccctcccgacttc ttctcggccgccttgcatggcagcggggagacgctcaggggagtgcccggctattgccac agctccctgccccgctcctacaaggctccctacacctgcaacggggacaacaacgaccag tatgtactcatgagctctccggtggggcgcatcctggaagaggagaggctggagccgctg gccagcccggggacggcgccgtccagcggctgcggcggtggcggccacgcccagcctcct cacccagcagtgccttcgcctggcaggccaggtggcagcgttggcggccgcccagagggc ttcctgaaccagcgctgccgggccgtgcggcccacgcgcctgtccctggaggggcttcag accctgcccagcatgcacgaatacccgctgccgcccgagcccaagagccccggcgagtac atcaacattgacttcggcgacgcgggagctcgcctgtcgcctcccgcgcccccgctgctg gcctcggccgcctcgtcgtcctcgctgctgtccgccagcagcccggcctcctccctgggc tcgggcaccccgggcacgagcggcgacagccgacagcgctccccgctgtccgactacatg aacctcgacttcagctcgcccaagtcacccaagccgggcccccagggcggggaccctgtg ggctcgctggacgccctcctgtcccccgaggcctcctccccctatccgccgctgcccccg cgccctgcggcgtctgcctccgccctgcagccgcagccgctgccgccgccccctccaggc gagctgtaccgcctgccccccgcccccgccgcccagggccccagcgctgcctcctcgtcg tcctcggagactggggacaatggtgactacaccgagatggccttcggcgtggctgccacc ccgccgcaacccatcgccgcccccccgaagccggaaggtgcccgcgtgaccagccccacg tccggcctcaagaggctgagtctcagggatcaagtgtcgggagtggaggccttcctgcag gccagccagcccccggacccgcaccggggggccaaggtcatccgcgcagacccgcagggg ggccgccgccgccacagctccgagaccttctcctcgaccaccactgtgacccccgtgtcc ccgtccttcgcccacaacccgaagcgccacaactcggcctccgtggaaaacgtctctctc aggaaaagcagcgaaggggcgggcggcggtggcctggctgggggcgacgagcgccccacg tccccccgccagctgcagccaccgcccccccagcaggcacggccgtggctaccgagtcag ccggggggcttggtcgggtgccccgggggcagcggctctccgatgcgcagggagacctct gccggcttccagaacggcctcaactacatcgccatcgacgtgagggacgaacctgggctg tcgcccggcccgcagcagcttccgcatccgcagccgggagacaagagcgcctggggccgg acccgtagcctggggggtctcctcagcgcggtggggggcggcagcaccggtggggtgtgc ggggggcccggccccggcgccctgccctccgccaacacctatgccagcattgacttcctg tcgcatcacctgaaggaggccaccattgtgaaagagtga

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