KEGG   Prionailurus bengalensis (leopard cat): 122490391
Entry
122490391         CDS       T07574                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase isoform X1
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg00670  One carbon pool by folate
pbg00790  Folate biosynthesis
pbg01100  Metabolic pathways
pbg01240  Biosynthesis of cofactors
pbg01523  Antifolate resistance
pbg04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    122490391 (DHFR)
   00670 One carbon pool by folate
    122490391 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    122490391 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    122490391 (DHFR)
Enzymes [BR:pbg01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     122490391 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 122490391
NCBI-ProteinID: XP_043449033
LinkDB
Position
A1:complement(145059131..145083180)
AA seq 212 aa
MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINIVLSRDLKEPPQGAHFLAKSLDDALELTEQPELAHKVDMVWVVGGSS
VYKINKEIDASCVFSKEAMNRPGHVRLFVTRIMQEFESDTFFPEIDLEKYKLLPEHVDSS
EVGFELGIEGSREMATDGQEEGRYMLPAEEKP
NT seq 639 nt   +upstreamnt  +downstreamnt
atggttcgtccgctaaactgtatcgtcgctgtgtcccagaacatgggcatcggcaagaac
ggggacctgccctggccgccgctcaggaatgaattcaagtatttccaaaggatgaccaca
acctcatccgtagaaggtaaacagaatttggtgattatgggtagaaagacatggttctct
attccggagaagaatcgacctttaaaggacagaattaacatagttctcagtagagacctc
aaggaacctccacaaggagctcattttcttgccaaaagtctggatgatgccttagaactt
actgagcaaccagaattagcacataaagtggacatggtttgggtagtgggaggcagttct
gtttataagataaataaagaaattgatgcctcttgtgttttttcaaaggaagccatgaac
aggccaggccacgttagactatttgtgacaaggattatgcaggagtttgaaagtgacaca
ttttttccagaaattgatttggagaaatataaacttctcccagaacatgtggactcttct
gaagtgggatttgagcttggtattgaaggatctagagagatggcgactgacggtcaggag
gaaggcagatatatgctcccggcagaggaaaaaccatga

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