Prionailurus bengalensis (leopard cat): 122491521 Help Entry 122491521         CDS       T07574                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism pbg  Prionailurus bengalensis (leopard cat) Pathway pbg00230   Purine metabolism pbg01100   Metabolic pathways pbg01522   Endocrine resistance pbg04015   Rap1 signaling pathway pbg04022   cGMP-PKG signaling pathway pbg04024   cAMP signaling pathway pbg04062   Chemokine signaling pathway pbg04072   Phospholipase D signaling pathway pbg04081   Hormone signaling pbg04082   Neuroactive ligand signaling pbg04114   Oocyte meiosis pbg04211   Longevity regulating pathway pbg04213   Longevity regulating pathway - multiple species pbg04261   Adrenergic signaling in cardiomyocytes pbg04270   Vascular smooth muscle contraction pbg04371   Apelin signaling pathway pbg04540   Gap junction pbg04611   Platelet activation pbg04713   Circadian entrainment pbg04714   Thermogenesis pbg04723   Retrograde endocannabinoid signaling pbg04724   Glutamatergic synapse pbg04725   Cholinergic synapse pbg04726   Serotonergic synapse pbg04727   GABAergic synapse pbg04728   Dopaminergic synapse pbg04750   Inflammatory mediator regulation of TRP channels pbg04911   Insulin secretion pbg04912   GnRH signaling pathway pbg04913   Ovarian steroidogenesis pbg04914   Progesterone-mediated oocyte maturation pbg04915   Estrogen signaling pathway pbg04916   Melanogenesis pbg04918   Thyroid hormone synthesis pbg04921   Oxytocin signaling pathway pbg04923   Regulation of lipolysis in adipocytes pbg04924   Renin secretion pbg04925   Aldosterone synthesis and secretion pbg04926   Relaxin signaling pathway pbg04927   Cortisol synthesis and secretion pbg04928   Parathyroid hormone synthesis, secretion and action pbg04934   Cushing syndrome pbg04935   Growth hormone synthesis, secretion and action pbg04970   Salivary secretion pbg04971   Gastric acid secretion pbg04972   Pancreatic secretion pbg04976   Bile secretion pbg05012   Parkinson disease pbg05030   Cocaine addiction pbg05031   Amphetamine addiction pbg05032   Morphine addiction pbg05034   Alcoholism pbg05163   Human cytomegalovirus infection pbg05166   Human T-cell leukemia virus 1 infection pbg05200   Pathways in cancer pbg05207   Chemical carcinogenesis - receptor activation pbg05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pbg00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     122491521 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     122491521 (ADCY5)    04371 Apelin signaling pathway     122491521 (ADCY5)    04072 Phospholipase D signaling pathway     122491521 (ADCY5)    04024 cAMP signaling pathway     122491521 (ADCY5)    04022 cGMP-PKG signaling pathway     122491521 (ADCY5)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     122491521 (ADCY5)    04081 Hormone signaling     122491521 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     122491521 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     122491521 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     122491521 (ADCY5)    04062 Chemokine signaling pathway     122491521 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     122491521 (ADCY5)    04923 Regulation of lipolysis in adipocytes     122491521 (ADCY5)    04912 GnRH signaling pathway     122491521 (ADCY5)    04913 Ovarian steroidogenesis     122491521 (ADCY5)    04915 Estrogen signaling pathway     122491521 (ADCY5)    04914 Progesterone-mediated oocyte maturation     122491521 (ADCY5)    04921 Oxytocin signaling pathway     122491521 (ADCY5)    04926 Relaxin signaling pathway     122491521 (ADCY5)    04935 Growth hormone synthesis, secretion and action     122491521 (ADCY5)    04918 Thyroid hormone synthesis     122491521 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     122491521 (ADCY5)    04916 Melanogenesis     122491521 (ADCY5)    04924 Renin secretion     122491521 (ADCY5)    04925 Aldosterone synthesis and secretion     122491521 (ADCY5)    04927 Cortisol synthesis and secretion     122491521 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     122491521 (ADCY5)    04270 Vascular smooth muscle contraction     122491521 (ADCY5)   09154 Digestive system    04970 Salivary secretion     122491521 (ADCY5)    04971 Gastric acid secretion     122491521 (ADCY5)    04972 Pancreatic secretion     122491521 (ADCY5)    04976 Bile secretion     122491521 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     122491521 (ADCY5)    04727 GABAergic synapse     122491521 (ADCY5)    04725 Cholinergic synapse     122491521 (ADCY5)    04728 Dopaminergic synapse     122491521 (ADCY5)    04726 Serotonergic synapse     122491521 (ADCY5)    04723 Retrograde endocannabinoid signaling     122491521 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     122491521 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     122491521 (ADCY5)    04213 Longevity regulating pathway - multiple species     122491521 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     122491521 (ADCY5)    04714 Thermogenesis     122491521 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122491521 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     122491521 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     122491521 (ADCY5)    05163 Human cytomegalovirus infection     122491521 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     122491521 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     122491521 (ADCY5)    05031 Amphetamine addiction     122491521 (ADCY5)    05032 Morphine addiction     122491521 (ADCY5)    05034 Alcoholism     122491521 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     122491521 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     122491521 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     122491521 (ADCY5) Enzymes [BR:pbg01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      122491521 (ADCY5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  122491521 NCBI-ProteinID:  XP_043450271 LinkDB All DBs Position C2:complement(69211377..69359076) Genome browser AA seq 1263 aa AA seqDB search MSGSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPHAPGGSTRSCTKKPGGA VTPQQQQQQRLANRWRNDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQ RRGAAGGGSTRAPPGGGGGGSAAAAAAAGGTEVRPRSVELGLEERRGKGRAADELEAGAG AVEGDEGSGDGSSSAGSGAGPGSVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLN QSSLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDHM GLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLS ALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQAR LHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGF TSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCV EMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAG GKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAK MNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDE FLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFV QITIVPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPAPLQTLSRKIVRSKTNSTLVG VFTITLVFLSAFVNMFMCNSKDLFGCLADEHNISTSQVNACHVVESAVNYSLGDERGFCS SPRPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELTYVLIVEVPRVTLFDNA DLLVTANAINFSNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLW KLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIA NFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDS TYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDI WGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGP PLS NT seq 3792 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgtaagccccccgggctacgcggcgcagacagcggcggcgccg gcgtcccggggaggcccggaacatcgctcggcgtggggggaggccgattcccgcgccaat ggctacccccacgcccccgggggttcgacccgcagctgcaccaagaaacccgggggggcg gtgaccccgcagcagcagcagcagcagcgcctggctaatcgttggcgcaacgacgacgac gacgatcctccgctgagtggtgacgaccctctggccgggggcttcggcttcagcttccgc tccaaatctgcttggcaggagcgcggcggcgacgactgcggtcgcggcagccgccggcag cggcggggcgcggccggcgggggcagcacccgggcgccccctgggggcggcggtggcggc tcggccgcggctgcggccgcagcgggcgggaccgaggtgcgccctcgctcggtggagctg ggcctggaggagcggcgcggcaagggccgcgcggcggacgagctggaggccggtgccggt gccgtcgagggcgacgaagggtcaggggatggcagcagctcggccggctcaggcgcgggg cccggctcagtgctgtcgctgggcgcctgctgcctggcgctgctgcagatattccgctcc aagaagttcccgtcggacaaactggagcggctgtaccagcgctacttcttccgtctgaac cagagcagcctcactatgcttatggccgtgctggtgctcgtgtgcctcgtcatgttggcc ttccacgcggcgcggcccccgctccagctgccctacctggcagtgctggcggccgcggtg ggtgtcatcctcgtcatggctgtgctctgtaaccgcgccgccttccaccaggaccacatg ggcctggcctgctacgcgctcatcgccgtggtgctggctgtccaggtggtgggcctgctg ctgccccagccgcgcagcgcctcggagggcatctggtggaccgtgttcttcatctacacc atctacacgttgctgcctgtgcgcatgcgggccgcggtactcagtggggtgctgctgtct gccctccacctggccatcgccctgcgcaccaacgcccaggaccagttcctgctcaagcag cttgtctccaatgtcctcattttctcctgcaccaacatcgtgggtgtctgcacccactac ccggctgaggtctctcagagacaggccttccaggaaacccgggagtgcatccaggcacgg ctccactcacaacgggagaaccagcaacaggagcggctcctgctgtctgtcctgccccgt catgttgccatggagatgaaagcagacatcaatgccaagcaggaggatatgatgttccat aagatttacatccagaaacatgacaacgtgagcatcctgtttgctgacatcgagggcttc accagcctggcgtcccagtgcactgcccaggagctagtcatgaccctcaatgagctcttc gcccgcttcgacaagctggctgcggagaatcactgtttacgtattaagatcctgggggat tgttattactgtgtctctgggctgcctgaagcgagggctgaccacgctcactgctgcgtg gagatgggcatggacatgattgaggccatctcgttggtccgggaggtgactggggtgaac gtgaacatgcgcgtgggaattcacagcgggcgagtacactgcggtgtccttggtctcagg aagtggcagttcgacgtctggtctaatgacgtcacgctggccaaccacatggaagctgga ggcaaggcagggcgcatccacatcaccaaggccacgctcaactacctgaatggtgactat gaggtggagccaggctgtgggggcgagcgcaacgcctacctcaaggagcacagcattgag accttcctcatcctgcgctgcacccagaagcggaaagaagaaaaggccatgatcgccaag atgaatcgccagagaaccaactccattgggcacaacccgccccactggggggctgagcgt cccttctacaaccacctagggggcaaccaggtgtccaaggagatgaagcggatgggcttt gaagaccccaaggacaagaacgcccaggaaagtgcaaaccccgaggatgaagtggacgaa tttctgggccgtgccattgacgccaggagcatcgacaggctgcggtctgagcatgtccgc aagttcctcttgaccttcagggagcctgacttagagaagaagtactccaagcaggtggat gaccgattcggtgcctatgtggcatgtgcctcgcttgtcttcctcttcatctgctttgtc cagatcaccatcgtgccccactccgtgttcatgttgagtttctacctgacctgtttcctg ctgctgaccttggtggtgtttgtgtccgtgatttattcctgcgtgaagctcttcccggcc ccgctgcagaccctttccaggaagatcgtgcggtccaagacaaacagcaccctggtcgga gtgttcaccatcaccctggtgttcctgtcggcttttgtcaacatgttcatgtgtaactcc aaggacctgttcggctgcctggcggacgagcacaacatcagcaccagccaggtcaacgcg tgccatgtggtggagtcggcagtcaactacagcctgggtgacgagcggggcttctgcagc agcccccggcccaactgcaacttccccgagtacttcacctacagcgtgctgctcagcctg ctagcctgctccgtgttcctgcagatcagctgcattgggaagctggtgctcatgctggcc attgagctcacatacgtgctcattgttgaggtgccccgcgtcacgctctttgacaacgcc gacctgctggtcaccgccaatgccataaacttcagcaacaacgggacctcccagtgccct gagcatgcgaccaaggtggcgctgaaggtggtgacgcccatcatcatctcagtcttcgtg ctggccctgtacctgcacgcccagcaagtagagtccaccgcccgcctggacttcctctgg aaactgcaggccacggaggaaaaggaggagatggaggagctgcaggcctacaaccggcgg ctgctgcacaacatcctgcccaaggatgtggccgcccacttcctggcccgcgagcgacgc aatgatgagctctactaccagtcgtgtgagtgcgtggctgtcatgttcgcctccatcgcc aacttctctgagttctacgtggagctggaggccaacaatgagggtgttgagtgcctgcga ctgctcaatgagattatcgccgactttgacgagatcatcagcgaggatcggttcaggcag ctggaaaagatcaagaccattggcagcacctacatggctgcctcaggcctcaatgactct acatatgacaaggtgggcaagacccacatcaaagccctggctgactttgccatgaagctc atggaccaaatgaagtacatcaatgagcactccttcaacaacttccagatgaagatcggg ctcaatattggccccgtggtggctggggtgatcggggctcgcaagcctcagtacgacatc tggggcaatacggtgaacgtggccagccgcatggacagcaccggtgtgcctgaccgcatc caggtcaccacagacatgtaccaggtgctggctgccaacacataccagctggagtgcagg ggcgtggtcaaggtcaagggcaaaggagagatgatgacctacttcctcaacggtgggccc ccgctcagttag

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