Prionailurus bengalensis (leopard cat): 122493456
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Entry
122493456 CDS
T07574
Symbol
PDGFRB
Name
(RefSeq) platelet-derived growth factor receptor beta isoform X1
KO
K05089
platelet-derived growth factor receptor beta [EC:
2.7.10.1
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg01521
EGFR tyrosine kinase inhibitor resistance
pbg04010
MAPK signaling pathway
pbg04014
Ras signaling pathway
pbg04015
Rap1 signaling pathway
pbg04020
Calcium signaling pathway
pbg04072
Phospholipase D signaling pathway
pbg04151
PI3K-Akt signaling pathway
pbg04510
Focal adhesion
pbg04518
Integrin signaling
pbg04540
Gap junction
pbg04630
JAK-STAT signaling pathway
pbg04810
Regulation of actin cytoskeleton
pbg05165
Human papillomavirus infection
pbg05200
Pathways in cancer
pbg05206
MicroRNAs in cancer
pbg05214
Glioma
pbg05215
Prostate cancer
pbg05218
Melanoma
pbg05230
Central carbon metabolism in cancer
pbg05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122493456 (PDGFRB)
04014 Ras signaling pathway
122493456 (PDGFRB)
04015 Rap1 signaling pathway
122493456 (PDGFRB)
04630 JAK-STAT signaling pathway
122493456 (PDGFRB)
04020 Calcium signaling pathway
122493456 (PDGFRB)
04072 Phospholipase D signaling pathway
122493456 (PDGFRB)
04151 PI3K-Akt signaling pathway
122493456 (PDGFRB)
09133 Signaling molecules and interaction
04518 Integrin signaling
122493456 (PDGFRB)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
122493456 (PDGFRB)
04540 Gap junction
122493456 (PDGFRB)
09142 Cell motility
04810 Regulation of actin cytoskeleton
122493456 (PDGFRB)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122493456 (PDGFRB)
05206 MicroRNAs in cancer
122493456 (PDGFRB)
05230 Central carbon metabolism in cancer
122493456 (PDGFRB)
05231 Choline metabolism in cancer
122493456 (PDGFRB)
09162 Cancer: specific types
05214 Glioma
122493456 (PDGFRB)
05218 Melanoma
122493456 (PDGFRB)
05215 Prostate cancer
122493456 (PDGFRB)
09172 Infectious disease: viral
05165 Human papillomavirus infection
122493456 (PDGFRB)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
122493456 (PDGFRB)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pbg01001
]
122493456 (PDGFRB)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pbg04090
]
122493456 (PDGFRB)
Enzymes [BR:
pbg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122493456 (PDGFRB)
Protein kinases [BR:
pbg01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
122493456 (PDGFRB)
CD molecules [BR:
pbg04090
]
Proteins
122493456 (PDGFRB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_PDGFR_d4
Pkinase
ig
Ig_3
I-set
Ig_2
V-set
VEGFR-1-like_Ig-like
VEGFR1-3_N_Ig-like
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
122493456
NCBI-ProteinID:
XP_043453986
LinkDB
All DBs
Position
A1:197692448..197730296
Genome browser
AA seq
1102 aa
AA seq
DB search
MQLPSAMPAPVLKGQVLLLPLLLLLGPQASWGLVITPPGPELVLNISSTFVLTCSGAAPV
VWERMSQKPLQKTAKNQDGTFSSTLTLTNVTGLDTGEYFCTYKNSLGPEPAERKRLYIFV
PDPTMGFLPVFPEDLFIFLTEISEITIPCRVTDPSLVVTLHEKKVDIPLPIPYDHQRGFS
GIFEDKTYVCKTIIGDREVDSEAYYVYSLQVSSINVSVNAVQTVVRQGENITIMCIVTGN
EVVNFEWTYPRMESGRLVEPVTDFLFNVPSHIRSILHIPNAELGDSGTYICNVSESVNDH
RDEKSINVTVVESGYVQLLGELDAVQFAELHRSRTLQVVFEAYPPPTVMWLKDNRTLGDS
SAGEIALSTRNVSETRYVSELTLVRVKVAEAGYYTMRAFHEDAEAQISFQLQVNVPVRVL
ELSENHPASGEQTVRCRGRGMPQPHLIWSTCSDLKRCPRELPPTPLGNSSEEDSQLETNV
TYWPEDQEFEVVSTLRLRRVDQPLSVRCTLHNLLGHDMQEVTVVPHSLPFKVVVISAILA
LVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQL
VLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGP
HLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQRCSDKRRPPSAELYSNAL
PTGLPLPSHVSLPGESDGGYMDMSKDESVDYVPMLDMKGGIKYADIESSSYVAPYDNYVP
TAPERTCRATLINESPVLSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLV
KICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLG
GTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLER
LLGEGYKKKYQQVDEEFLRSDHPAVLRSQARFPGFNGLRSPLDTSSVLYTAVQPNESDND
YIIPLPDPKPEIADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQEEPEPEPQLEPQV
EPEPPLDSCCPGPRAEAEDSFL
NT seq
3309 nt
NT seq
+upstream
nt +downstream
nt
atgcagctcccgagcgccatgccagctcctgtcctcaaaggccaggtgctgttgctgccc
ctgctgttgctgctgggaccacaggcctcctggggcctggtcatcacacctccggggcca
gagcttgtcctcaatatctccagcaccttcgttctgacctgttcgggtgcagctccggtg
gtgtgggaacggatgtcccagaagcccctgcagaaaacggccaagaaccaggatggcacc
ttctccagcacactgacactgaccaatgtcactgggctagacacgggagaatacttttgc
acctacaaaaactccctcgggccggagcctgctgagcgaaaacggctctacatctttgtg
ccagatccgactatgggctttcttccggtcttccccgaggacctgttcatctttctcacg
gaaatatctgagatcacaattccctgccgagtgacggatccgagtctggtggtgacactg
cacgagaagaaagtggatattccactgcccatcccctatgaccaccaacgtggcttctct
ggtatcttcgaggacaagacctatgtctgcaaaaccatcatcggggacagggaagtggat
tctgaagcctactatgtctacagtctccaggtgtcgtccatcaatgtctcagtgaatgca
gtgcagactgtggtccgccagggtgagaacatcaccatcatgtgcattgtgaccggaaat
gaggtggtcaactttgaatggacatacccacgcatggagagtgggcggctggtggagcca
gtgactgacttcctcttcaatgtaccctcccacatacgctccatcctgcacatccctaat
gccgagcttggcgattcagggacctacatctgcaatgtatcggagagtgtgaatgaccat
cgagatgaaaagtccatcaatgtcactgtggttgagagtggctacgtgcagctgctggga
gagctggacgccgtacaattcgcggagctgcaccgcagccggactctgcaggtggtgttc
gaggcatacccgccgcctactgtcatgtggctcaaggacaaccgcacgctaggcgactcc
agcgcaggcgagattgccctgtccacacgcaatgtgtctgagacccggtatgtgtcagaa
ctgacattggtgcgggtgaaggtggctgaggctggctactacaccatgcgggccttccac
gaggatgcagaggcccagatctccttccagctgcaggtcaatgtgcctgtccgtgtgctg
gagctgagtgaaaaccatcctgccagcggggagcagacagtccgctgtcgcggccggggc
atgccccagccacacctcatctggtctacctgcagtgacctcaaaagatgtcctcgcgaa
ctgccgcccaccccactggggaacagttccgaggaggacagccagctggagactaacgtg
acttactggcctgaggatcaggagttcgaggtggtgagcacgctgcgcctgcgccgtgtg
gatcagcctctgtccgtgcgctgcactctgcacaacctgctgggccacgacatgcaggag
gtcaccgtggtgccacattctctgcccttcaaggtggtggtgatctcggccatcctggcc
ttggtggtcctcacaatcatctccctcatcatcctcatcatgctctggcagaagaagcca
cgttatgagatccgatggaaggtgattgaatctgtgagctctgatggccatgagtacatc
tacgtggaccctatgcagctgccctatgactctacctgggagctgccacgggaccagctt
gtgcttggacgcaccctcggctctggggcctttgggcaggtggtggaggccacagctcac
ggcctgagccattctcaggccacgatgaaagtggcggtcaagatgctgaaatccacagcc
cgcagcagcgagaagcaggccctcatgtcagagctgaagatcatgagtcaccttgggccc
catctgaacgtggtcaacttgctgggggcctgcaccaaaggaggacccatctacatcatc
acggagtactgccgctatggcgacctggtggactaccttcaccgcaacaagcacaccttc
ctgcagcgctgctccgacaagcgccgcccgcccagcgccgagctctacagcaacgccctg
cccacagggctccctctgcccagccacgtgtccctgcctggggagagtgacggcggctac
atggacatgagcaaggacgagtcggtggactacgtgcccatgctggacatgaaaggagga
atcaaatatgcagacatcgagtcctccagctacgtggccccttatgacaactacgtcccc
acagctcccgagaggacctgtcgggcaactctgatcaacgagtccccggtgcttagctac
acagatcttgtgggcttcagctaccaggtggccaatggcatggagttcctggcctccaag
aactgcgtccaccgagatctggcagccaggaacgtgctcatctgtgagggcaagctggtc
aagatctgtgactttggcctggctcgtgacatcatgagggactcgaactatatctccaaa
ggcagcaccttcctgcctctgaagtggatggctcccgagagcatcttcaacagcctctat
accaccctgagtgatgtgtggtccttcgggatcctactctgggagatcttcaccctgggt
ggcaccccttacccagagctgcccatgaatgagcagttctataatgccatcaagcggggt
taccgaatggcccaacctgcccatgcctccgatgagatctacgagatcatgcagaagtgc
tgggaagagaagtttgagatccggcctcccttctcccagctggtgctgcttcttgagagg
ctgctgggtgagggctacaagaagaagtaccagcaggtggatgaggagtttctgaggagc
gaccacccagctgtccttcggtcccaagcccgctttcctggcttcaatggactccgatcc
cccctggacaccagctctgtgctctacactgctgtgcagcccaatgagagtgacaatgac
tatatcatccccctgcctgaccccaaacctgagattgctgatgagggccccctggagggt
tcccccagccttgccagctccaccctgaatgaagtcaacacctcctctaccatctcctgc
gacagccccctggaaccccaagaggagccagagccagaaccccagctcgagccccaggtg
gagccagagccaccactggattcatgttgccctgggcctcgggccgaggcggaggacagc
ttcctgtag
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