KEGG   Prionailurus bengalensis (leopard cat): 122494216
Entry
122494216         CDS       T07574                                 
Symbol
MMP2
Name
(RefSeq) 72 kDa type IV collagenase
  KO
K01398  matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg01522  Endocrine resistance
pbg04670  Leukocyte transendothelial migration
pbg04912  GnRH signaling pathway
pbg04915  Estrogen signaling pathway
pbg04926  Relaxin signaling pathway
pbg04933  AGE-RAGE signaling pathway in diabetic complications
pbg05200  Pathways in cancer
pbg05205  Proteoglycans in cancer
pbg05219  Bladder cancer
pbg05415  Diabetic cardiomyopathy
pbg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    122494216 (MMP2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    122494216 (MMP2)
   04915 Estrogen signaling pathway
    122494216 (MMP2)
   04926 Relaxin signaling pathway
    122494216 (MMP2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122494216 (MMP2)
   05205 Proteoglycans in cancer
    122494216 (MMP2)
  09162 Cancer: specific types
   05219 Bladder cancer
    122494216 (MMP2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    122494216 (MMP2)
   05415 Diabetic cardiomyopathy
    122494216 (MMP2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    122494216 (MMP2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    122494216 (MMP2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:pbg01002]
    122494216 (MMP2)
Enzymes [BR:pbg01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.24  gelatinase A
     122494216 (MMP2)
Peptidases and inhibitors [BR:pbg01002]
 Metallo peptidases
  Family M10
   122494216 (MMP2)
SSDB
Motif
Pfam: Peptidase_M10 fn2 Hemopexin PG_binding_1 Reprolysin_3 Reprolysin_5 Peptidase_M66
Other DBs
NCBI-GeneID: 122494216
NCBI-ProteinID: XP_043455154
LinkDB
Position
E2:33297527..33321113
AA seq 661 aa
MTEARGARGALAGPLRALCVLGCLLGRAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYG
CPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQSTIETMRKPRCGNPDVANYNFFPRKPKW
DKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHG
DGYPFDGKDGLLAHAFAPGPGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLF
NGKEYTSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQG
TSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNK
HESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGA
LMAPIYTYTKNFRLSHDDIKGIQELYGASPDIDTGTGPTPTLGPVTPEICKQDIVFDGIS
QIRGEIFFFKDRFIWRTVTPRSKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNE
YWVYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNRKTYIFAGDKFWRYNEVKKKMD
PGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLG
C
NT seq 1986 nt   +upstreamnt  +downstreamnt
atgaccgaggcgcgaggggcccggggcgcgctcgccggcccgctgcgggcgctctgcgtc
ctgggctgcctgttgggccgcgccgccgccgcgccgtcgcccatcatcaagttccctgga
gatgtggcccccaaaacggacaaagagctggccgtgcaatatctgaacaccttctacggc
tgccccaaggagagctgtaacctgttcgtgctcaaggacacactaaagaagatgcagaag
ttctttgggctgccccagacgggtgaccttgaccagagcacgattgagaccatgcggaag
cctcgctgtggcaaccctgatgtggccaactacaacttcttcccccgcaagcccaagtgg
gacaagaaccagatcacatacaggatcattggctacacgcctgatctggaccccgagaca
gtggatgatgcctttgctcgtgccttccaagtctggagtgatgtaaccccgctaaggttt
tctcgtatccacgatggagaggcggacatcatgatcaactttggccgctgggagcacgga
gatggatacccctttgatggcaaggacgggctcctggctcacgcctttgccccgggccct
ggcgtcgggggagactcccactttgacgacgatgagctgtggaccctgggagaagggcaa
gtggtccgcgtgaagtacgggaacgctgacggggagtactgcaagttccccttcctgttc
aacggcaaggaatacaccagctgcacggacacgggccgcagcgacggcttcctctggtgc
tccaccacctacaactttgaaaaggatggcaaatatggcttctgcccccacgaagccctg
ttcaccatgggtggcaatgctgacggacagccctgcaagttcccattccgcttccaggga
acatcctacgacagctgcaccaccgagggccgcaccgacggctaccgctggtgcgggacc
acggaagactacgaccgagacaagaagtatggcttctgccccgagaccgccatgtccact
gttggcgggaactcagaaggtgccccctgtgtcttccccttcaccttcttgggcaacaag
catgagagctgtacgagcgcgggccgcagcgatgggaagatgtggtgtgcgaccacggcc
aactatgacgatgaccgcaagtggggcttctgccctgaccaagggtacagcttgttcctg
gttgcagcccatgagtttggccatgcaatggggctggagcactctcaggaccctggggcc
ctgatggcacccatttatacctacaccaagaacttccgcctgtcccacgacgacatcaag
ggcattcaagagctctatggggcctcccctgatattgacactggcaccggccccacccca
actctcggccccgtcactcctgagatctgcaaacaggacattgtttttgatggcatctct
cagatccggggggagatcttcttcttcaaggacaggttcatttggcgaacagtgacacca
cgtagcaagcccatggggcccctgctggtggccacattctggcctgagctcccggaaaag
attgatgctgtatacgaggccccacaggaagagaaggctgtgttctttgcagggaatgaa
tactgggtctattcagccagcaccctggagcgagggtaccccaagccgctgaccagcctg
gggctgccccctgacgtccagcgggtagatgctgcgttcaactggagcaagaacaggaag
acctacatctttgctggagacaagttctggaggtacaatgaagtaaagaagaagatggac
cctggcttccccaagctcatcgcggatgcctggaacgccatccccgataacctggacgcc
gtggtcgacctgcagggcggtggtcacagctacttcttcaagggcgcgtattacctgaag
ttggagaaccagagtctgaagagcgtgaaatttggaagcatcaaatccgactggctgggc
tgctga

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