KEGG   Petaurus breviceps papuanus (sugar glider): 138152519
Entry
138152519         CDS       T10505                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
pbrv  Petaurus breviceps papuanus (sugar glider)
Pathway
pbrv01521  EGFR tyrosine kinase inhibitor resistance
pbrv01522  Endocrine resistance
pbrv04010  MAPK signaling pathway
pbrv04012  ErbB signaling pathway
pbrv04014  Ras signaling pathway
pbrv04062  Chemokine signaling pathway
pbrv04068  FoxO signaling pathway
pbrv04072  Phospholipase D signaling pathway
pbrv04150  mTOR signaling pathway
pbrv04151  PI3K-Akt signaling pathway
pbrv04380  Osteoclast differentiation
pbrv04510  Focal adhesion
pbrv04517  IgSF CAM signaling
pbrv04540  Gap junction
pbrv04550  Signaling pathways regulating pluripotency of stem cells
pbrv04630  JAK-STAT signaling pathway
pbrv04650  Natural killer cell mediated cytotoxicity
pbrv04660  T cell receptor signaling pathway
pbrv04662  B cell receptor signaling pathway
pbrv04664  Fc epsilon RI signaling pathway
pbrv04714  Thermogenesis
pbrv04722  Neurotrophin signaling pathway
pbrv04910  Insulin signaling pathway
pbrv04912  GnRH signaling pathway
pbrv04915  Estrogen signaling pathway
pbrv04917  Prolactin signaling pathway
pbrv04926  Relaxin signaling pathway
pbrv04935  Growth hormone synthesis, secretion and action
pbrv05034  Alcoholism
pbrv05160  Hepatitis C
pbrv05161  Hepatitis B
pbrv05163  Human cytomegalovirus infection
pbrv05165  Human papillomavirus infection
pbrv05200  Pathways in cancer
pbrv05203  Viral carcinogenesis
pbrv05205  Proteoglycans in cancer
pbrv05206  MicroRNAs in cancer
pbrv05207  Chemical carcinogenesis - receptor activation
pbrv05208  Chemical carcinogenesis - reactive oxygen species
pbrv05210  Colorectal cancer
pbrv05211  Renal cell carcinoma
pbrv05213  Endometrial cancer
pbrv05214  Glioma
pbrv05215  Prostate cancer
pbrv05220  Chronic myeloid leukemia
pbrv05221  Acute myeloid leukemia
pbrv05223  Non-small cell lung cancer
pbrv05224  Breast cancer
pbrv05225  Hepatocellular carcinoma
pbrv05226  Gastric cancer
pbrv05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pbrv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    138152519 (GRB2)
   04012 ErbB signaling pathway
    138152519 (GRB2)
   04014 Ras signaling pathway
    138152519 (GRB2)
   04630 JAK-STAT signaling pathway
    138152519 (GRB2)
   04068 FoxO signaling pathway
    138152519 (GRB2)
   04072 Phospholipase D signaling pathway
    138152519 (GRB2)
   04151 PI3K-Akt signaling pathway
    138152519 (GRB2)
   04150 mTOR signaling pathway
    138152519 (GRB2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    138152519 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    138152519 (GRB2)
   04540 Gap junction
    138152519 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    138152519 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    138152519 (GRB2)
   04660 T cell receptor signaling pathway
    138152519 (GRB2)
   04662 B cell receptor signaling pathway
    138152519 (GRB2)
   04664 Fc epsilon RI signaling pathway
    138152519 (GRB2)
   04062 Chemokine signaling pathway
    138152519 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    138152519 (GRB2)
   04912 GnRH signaling pathway
    138152519 (GRB2)
   04915 Estrogen signaling pathway
    138152519 (GRB2)
   04917 Prolactin signaling pathway
    138152519 (GRB2)
   04926 Relaxin signaling pathway
    138152519 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    138152519 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    138152519 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    138152519 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    138152519 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    138152519 (GRB2)
   05206 MicroRNAs in cancer
    138152519 (GRB2)
   05205 Proteoglycans in cancer
    138152519 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    138152519 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    138152519 (GRB2)
   05203 Viral carcinogenesis
    138152519 (GRB2)
   05231 Choline metabolism in cancer
    138152519 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    138152519 (GRB2)
   05225 Hepatocellular carcinoma
    138152519 (GRB2)
   05226 Gastric cancer
    138152519 (GRB2)
   05214 Glioma
    138152519 (GRB2)
   05221 Acute myeloid leukemia
    138152519 (GRB2)
   05220 Chronic myeloid leukemia
    138152519 (GRB2)
   05211 Renal cell carcinoma
    138152519 (GRB2)
   05215 Prostate cancer
    138152519 (GRB2)
   05213 Endometrial cancer
    138152519 (GRB2)
   05224 Breast cancer
    138152519 (GRB2)
   05223 Non-small cell lung cancer
    138152519 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    138152519 (GRB2)
   05160 Hepatitis C
    138152519 (GRB2)
   05163 Human cytomegalovirus infection
    138152519 (GRB2)
   05165 Human papillomavirus infection
    138152519 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    138152519 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    138152519 (GRB2)
   01522 Endocrine resistance
    138152519 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pbrv04131]
    138152519 (GRB2)
Membrane trafficking [BR:pbrv04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    138152519 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 SH2_2 DUF5093 DUF7145 hSH3 SH3_4
Other DBs
NCBI-GeneID: 138152519
NCBI-ProteinID: XP_068932539
LinkDB
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLGKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIQVLDNSDPNWWKGACHGQTGMFPRNYVTPVNRNI
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatagccaaatacgacttcaaagccactgcagatgatgagttgagcttcaaa
aggggtgacatcctcaaggtgctgaatgaagaatgtgatcaaaattggtataaggcagaa
ctcaatggaaaagatggcttcattcccaagaactacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagcaaaggcagaagaaatgcttggcaaacagcgacatgat
ggtgcctttcttatccgggagagtgagagtgcaccgggggacttctccctttctgtcaag
tttggaaatgatgtgcaacatttcaaggtgctccgagatggggctgggaagtatttcctt
tgggtggtaaagttcaattctttaaatgagctggtagattatcacagatccacctcagtt
tccagaaaccagcaaatattcttgcgggacatagaacaggtgccacagcaaccaacatat
gtccaggccctctttgactttgacccccaagaagatggagagctgggcttccgtcgggga
gatttcatacaggtcctcgataactcagaccccaactggtggaaaggagcttgccatggg
cagaccggcatgtttccacgtaactacgtcaccccagtgaaccggaacatctaa

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