Physeter macrocephalus (sperm whale): 102975211 Help Entry 102975211         CDS       T06011                                  Symbol ADCY8 Name (RefSeq) adenylate cyclase type 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism pcad  Physeter macrocephalus (sperm whale) Pathway pcad00230   Purine metabolism pcad01100   Metabolic pathways pcad01522   Endocrine resistance pcad04015   Rap1 signaling pathway pcad04020   Calcium signaling pathway pcad04022   cGMP-PKG signaling pathway pcad04024   cAMP signaling pathway pcad04062   Chemokine signaling pathway pcad04072   Phospholipase D signaling pathway pcad04081   Hormone signaling pcad04082   Neuroactive ligand signaling pcad04114   Oocyte meiosis pcad04211   Longevity regulating pathway pcad04213   Longevity regulating pathway - multiple species pcad04261   Adrenergic signaling in cardiomyocytes pcad04270   Vascular smooth muscle contraction pcad04371   Apelin signaling pathway pcad04540   Gap junction pcad04611   Platelet activation pcad04713   Circadian entrainment pcad04714   Thermogenesis pcad04720   Long-term potentiation pcad04723   Retrograde endocannabinoid signaling pcad04724   Glutamatergic synapse pcad04725   Cholinergic synapse pcad04727   GABAergic synapse pcad04742   Taste transduction pcad04750   Inflammatory mediator regulation of TRP channels pcad04911   Insulin secretion pcad04912   GnRH signaling pathway pcad04913   Ovarian steroidogenesis pcad04914   Progesterone-mediated oocyte maturation pcad04915   Estrogen signaling pathway pcad04916   Melanogenesis pcad04918   Thyroid hormone synthesis pcad04921   Oxytocin signaling pathway pcad04923   Regulation of lipolysis in adipocytes pcad04925   Aldosterone synthesis and secretion pcad04926   Relaxin signaling pathway pcad04927   Cortisol synthesis and secretion pcad04928   Parathyroid hormone synthesis, secretion and action pcad04934   Cushing syndrome pcad04935   Growth hormone synthesis, secretion and action pcad04970   Salivary secretion pcad04971   Gastric acid secretion pcad04972   Pancreatic secretion pcad04976   Bile secretion pcad05032   Morphine addiction pcad05163   Human cytomegalovirus infection pcad05166   Human T-cell leukemia virus 1 infection pcad05200   Pathways in cancer pcad05207   Chemical carcinogenesis - receptor activation pcad05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pcad00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102975211 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102975211 (ADCY8)    04072 Phospholipase D signaling pathway     102975211 (ADCY8)    04024 cAMP signaling pathway     102975211 (ADCY8)    04022 cGMP-PKG signaling pathway     102975211 (ADCY8)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102975211 (ADCY8)    04081 Hormone signaling     102975211 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102975211 (ADCY8)    04062 Chemokine signaling pathway     102975211 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     102975211 (ADCY8)    04923 Regulation of lipolysis in adipocytes     102975211 (ADCY8)    04913 Ovarian steroidogenesis     102975211 (ADCY8)    04915 Estrogen signaling pathway     102975211 (ADCY8)    04921 Oxytocin signaling pathway     102975211 (ADCY8)    04926 Relaxin signaling pathway     102975211 (ADCY8)    04935 Growth hormone synthesis, secretion and action     102975211 (ADCY8)    04918 Thyroid hormone synthesis     102975211 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     102975211 (ADCY8)    04925 Aldosterone synthesis and secretion     102975211 (ADCY8)    04927 Cortisol synthesis and secretion     102975211 (ADCY8)   09154 Digestive system    04970 Salivary secretion     102975211 (ADCY8)    04971 Gastric acid secretion     102975211 (ADCY8)    04972 Pancreatic secretion     102975211 (ADCY8)    04976 Bile secretion     102975211 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     102975211 (ADCY8)    04727 GABAergic synapse     102975211 (ADCY8)    04725 Cholinergic synapse     102975211 (ADCY8)    04720 Long-term potentiation     102975211 (ADCY8)    04723 Retrograde endocannabinoid signaling     102975211 (ADCY8)   09157 Sensory system    04742 Taste transduction     102975211 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     102975211 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     102975211 (ADCY8)    04213 Longevity regulating pathway - multiple species     102975211 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     102975211 (ADCY8)    04714 Thermogenesis     102975211 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102975211 (ADCY8)    05207 Chemical carcinogenesis - receptor activation     102975211 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102975211 (ADCY8)    05163 Human cytomegalovirus infection     102975211 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     102975211 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102975211 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102975211 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102975211 (ADCY8) Enzymes [BR:pcad01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102975211 (ADCY8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD Motif Other DBs NCBI-GeneID:  102975211 NCBI-ProteinID:  XP_007102035 Ensembl:  ENSPCTG00005021141 UniProt:  A0A2Y9EGS6 LinkDB All DBs Position 15:9344607..9568291 Genome browser AA seq 1247 aa AA seqDB search MELSDVRCLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFVHGHRGSGGG RGSSSKASDPVGGGPNHHASQLAGDSALPLYALGPGERAHSPGCTKVFPERSGSGGGGGA GDLGFLHLDCAPSNSDFFLKGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVV MNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQY SGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQV VLQGVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLE TENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFT NLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVE MGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGG IPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDIVKE SVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGP EEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLL FITAIQSLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINETYLA RNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAM VTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDSLNHSGEDFLGTKEASLLL MAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFL EKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGE DRFQDIEKIKTIGSTYMAVSGLSPEKQQCEAKWEHLCALADFSLALTESIQEINKHSFNN FELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQG FAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLN RQRQKQLLNENNNTGIIKGHYNRRTLLTPSGPEPGAQAEGTDKSELP NT seq 3744 nt NT seq  +upstreamnt  +downstreamnt atggagctctccgatgtgcgctgccttagcggcagcgaggagctctacaccatccacccg acgcccccggccggcgacggcgggagcggctcccggccgcagcggctgctgtggcaaacg gcggtgcggcacatcaccgagcagcgcttcgttcacgggcaccggggcagtggcggcggc cgcggaagctccagcaaagcctcggaccctgtaggcggcggccccaaccaccacgcgtcg cagctggccggcgactctgcgctgcccctctacgcgctgggccccggggagagagcgcac agccccggctgcaccaaagtcttcccggaacgcagcggcagcggcggcggcgggggcgcg ggcgacctgggcttcctgcacctcgactgcgccccgagcaactcggatttcttcctcaag gggggctacagctaccgaggggtcattttccccaccctgcgcaactccttcaagtcccgg gatctggagcgcctctaccagcgctatttcctgggccagaggcgcaagtcggaggtggtg atgaacgtgctggacgtgctgaccaaactcaccctcttggttctccacttgagcctggcc tcggcccccatggacccgctcaagggcatcctgctgggcttcttcacgggcatagaggtg gtgatctgcgccttggtggtggtcaggaaggacaccacctctcacacctacctgcagtac agcggcgtggtcacctgggtggccatgaccacccagatcttagcagcaggtctgggctat gggctcctgggagacggcattggctacgtgctcttcaccctcttcgccacctacagcatg ctgccgctgccgcttacctgggccatcctggctggcctgggcacgtcgttactgcaggtg gtcctccaaggggtcatccccaggctggcggtcatttccatcaaccaggttgtggcccag gcagtgttattcatgtgtatgaacacggctggaatctttatcagttacctgtcagaccgg gcccagcgccaagccttcctggagacgcggaggtgtgtggaagccaggctgcgcctcgag acggaaaaccaaagacaggagcggcttgtgctgtctgtgcttcctcggtttgtcgtcctg gagatgatcaatgacatgaccaacgtggaagacgagcacctgcagcatcaattccaccgg atctacatccaccgctacgagaatgtcagtattctttttgcagatgttaaaggatttacc aacctctccacgaccttgtctgcccaggagctcgtcaggatgctcaacgagctctttgcc agatttgatcgactggcccatgagcatcactgccttcgcattaaaatcctgggagactgc tactactgcgtttcaggacttcctgagccccgccaggaccacgcccactgctgcgttgaa atgggcctcagtatgatcaaaaccatcaggtatgtgcggtcaaggacgaagcatgatgtt gacatgcggattggaatccactcgggctcagtgctatgtggcgtgttgggtctacggaag tggcagtttgatgtctggtcttgggatgtggatattgcaaacaaacttgaatctggagga atccctgggcggattcacatttccaaagccacgctggactgcctcaatggtgactataat gtggaagagggtcatggcaaagagaggaacgaattcttgaggaagcataatatagagacc tatttaatcaagcagcctgaggagagtcttctgtctttgcctgaagacatcgtcaaggaa tctgtgagctcctcagacaggagaaacagtggggcgacgttcacagaaggatcctggagc cccgagctgccctttgataacatagtggggaaacagaacactctggctgccctaacaaga aattcaataaatctacttccaaaccatcttgcacaagctttgcatgtccagtctgggcct gaggaaattaacaagagaatagaacataccatcgacttgcggagtggcgataaattgaga agagagcatatcaagccattctcactgatgtttaaagactccagcctggagcacaagtat tctcaaatgagggatgaagtattcaaatcaaacttggtctgtgcgtttatcgttcttctg tttatcacggcaatacaaagtttgcttccttcttcaagggtgatgccaatggccatccag ttttccatcctgattatgctgcactcggctctggtcctcatcaccacagcggaggattat aagtgtttgcccctggtcctccggaaaacttgctgttggattaacgagacctatttggcc aggaatgtcatcatctttgcgtccatcttgattaatttcctgggcgccatcttaaatatc ctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttcaattcctcagct gtgtttacagatatctgctcctacccagagtacttcgtcttcacgggggtgttggccatg gtgacctgtgcggttttcctccgacttaactctgtcctgaagctggctgtgctgctgatt atgatcgccatctacgccctgctgaccgagaccatctatgcaggactcttcctgcgctat gacagcctgaatcacagtggagaagatttcctggggaccaaggaggcgtcactgctgctg atggccatgttcctcctcgctgtcttctaccatggacagcagctggagtacacagcgcgc ctggacttcctctggcgagttcaggccaaagaggagatcaacgagatgaaggagctgagg gaacacaacgagaacatgctccggaacatcctacccagtcacgtggcccgccacttcctg gagaaagaccgggacaatgaggagctgtattctcaatcctatgatgccgttggggtgatg tttgcctccatcccagggtttgcagacttctactctcagactgaaatgaacaaccaagga gtggaatgcctacgcctgctgaatgagatcatcgccgacttcgatgagctgcttggtgaa gaccggtttcaagacattgaaaagattaagaccattggcagcacctacatggccgtgtca ggcctgtcacctgaaaaacagcaatgtgaagctaagtgggaacatttgtgcgccctggcc gacttctctctcgccctgaccgaaagcatacaggagatcaacaagcattctttcaacaat tttgagctccggattggcatcagccacggctcagtggtagctggcgttatcggcgctaag aaaccacagtatgacatttggggcaaaaccgtgaacctggcaagtcgaatggacagcacg ggagtcagcggcagaatccaggtcccagaggagacctatctcatcctgaaggaccagggc tttgcctttgactaccgaggggagatctacgtgaagggcatcagtgaacaggagggaaaa atcaaaacgtactttctcctgggaagagtccaacccaacccgttcatcctgccgccgaga aggctgcccgggcagtattccttggccgcggtcgtcctgggcctcgtccagtccctgaac aggcaaaggcagaagcagctgctgaatgagaacaacaacacgggcatcatcaagggccat tacaaccggcggactttgctgacacccagtgggcctgagccgggagcccaagccgaaggc accgacaagtccgagttgccataa

DBGET integrated database retrieval system