KEGG   Physeter macrocephalus (sperm whale): 102975643
Entry
102975643         CDS       T06011                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X1
  KO
K13375  transforming growth factor beta-1
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad04010  MAPK signaling pathway
pcad04060  Cytokine-cytokine receptor interaction
pcad04068  FoxO signaling pathway
pcad04110  Cell cycle
pcad04148  Efferocytosis
pcad04218  Cellular senescence
pcad04350  TGF-beta signaling pathway
pcad04380  Osteoclast differentiation
pcad04390  Hippo signaling pathway
pcad04518  Integrin signaling
pcad04659  Th17 cell differentiation
pcad04672  Intestinal immune network for IgA production
pcad04926  Relaxin signaling pathway
pcad04932  Non-alcoholic fatty liver disease
pcad04933  AGE-RAGE signaling pathway in diabetic complications
pcad05140  Leishmaniasis
pcad05142  Chagas disease
pcad05144  Malaria
pcad05145  Toxoplasmosis
pcad05146  Amoebiasis
pcad05152  Tuberculosis
pcad05161  Hepatitis B
pcad05166  Human T-cell leukemia virus 1 infection
pcad05200  Pathways in cancer
pcad05205  Proteoglycans in cancer
pcad05210  Colorectal cancer
pcad05211  Renal cell carcinoma
pcad05212  Pancreatic cancer
pcad05220  Chronic myeloid leukemia
pcad05225  Hepatocellular carcinoma
pcad05226  Gastric cancer
pcad05321  Inflammatory bowel disease
pcad05323  Rheumatoid arthritis
pcad05410  Hypertrophic cardiomyopathy
pcad05414  Dilated cardiomyopathy
pcad05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102975643 (TGFB1)
   04350 TGF-beta signaling pathway
    102975643 (TGFB1)
   04390 Hippo signaling pathway
    102975643 (TGFB1)
   04068 FoxO signaling pathway
    102975643 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    102975643 (TGFB1)
   04518 Integrin signaling
    102975643 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102975643 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    102975643 (TGFB1)
   04218 Cellular senescence
    102975643 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    102975643 (TGFB1)
   04672 Intestinal immune network for IgA production
    102975643 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    102975643 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102975643 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102975643 (TGFB1)
   05205 Proteoglycans in cancer
    102975643 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102975643 (TGFB1)
   05212 Pancreatic cancer
    102975643 (TGFB1)
   05225 Hepatocellular carcinoma
    102975643 (TGFB1)
   05226 Gastric cancer
    102975643 (TGFB1)
   05220 Chronic myeloid leukemia
    102975643 (TGFB1)
   05211 Renal cell carcinoma
    102975643 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102975643 (TGFB1)
   05161 Hepatitis B
    102975643 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    102975643 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102975643 (TGFB1)
   05144 Malaria
    102975643 (TGFB1)
   05145 Toxoplasmosis
    102975643 (TGFB1)
   05140 Leishmaniasis
    102975643 (TGFB1)
   05142 Chagas disease
    102975643 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    102975643 (TGFB1)
   05321 Inflammatory bowel disease
    102975643 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    102975643 (TGFB1)
   05414 Dilated cardiomyopathy
    102975643 (TGFB1)
   05415 Diabetic cardiomyopathy
    102975643 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102975643 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102975643 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:pcad03110]
    102975643 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:pcad04052]
    102975643 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:pcad00536]
    102975643 (TGFB1)
Chaperones and folding catalysts [BR:pcad03110]
 Intramolecular chaperones
  Others
   102975643 (TGFB1)
Cytokines and neuropeptides [BR:pcad04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   102975643 (TGFB1)
Glycosaminoglycan binding proteins [BR:pcad00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   102975643 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 102975643
NCBI-ProteinID: XP_023988444
Ensembl: ENSPCTG00005016912
UniProt: A0A2Y9TIY3
LinkDB
Position
Unknown
AA seq 391 aa
MPPSGLRLLPLLLPLLWLLVLPPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVENSNEI
YGKIKRSPHSMYMLFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNDSWR
YLSNRLLAPSDSPEWLSFDVTGVVRQWLTHGEEIEGFRLSAHCSCDSKDNTLQVDINAGF
SSGRRGDLATIHGMNRPFLLLMATPLERAQHLHSPRHRRALDTNYCFSSTEKNCCVRQLY
IDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQ
ALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1176 nt   +upstreamnt  +downstreamnt
atgccgccctcggggctgcggctgctgccgctgctgctgccgctgctgtggctactagtg
ctgccgcctggccggccggccgccggactgtccacctgcaagaccatcgacatggagctg
gtgaagcgaaagcgcatcgaggccatccgaggccagattctgtccaagcttcggctcgcc
agccccccgagccagggggaggtgccgcccggtccgctgcccgaggccgtactggcgctt
tacaacagtacccgtgaccgggtggccggggaaagtgccgaacctgagcctgagccagag
gcggactactacgccaaggaggtcacccgcgtgctcatggtggaaaacagcaacgaaatc
tatgggaagatcaagcgtagcccacacagcatgtatatgctcttcaacacgtccgagctc
cgggaagcggtgcccgaacctgtgttgctctctcgggcagagctgcgcctgctgaggctc
aagttaaaagtggagcagcacgtggagctgtaccagaaatacagcaatgattcctggcgc
tacctcagcaaccggctgctggcccccagcgactcaccagagtggctgtcctttgatgtc
actggagttgtgcggcagtggctgacccacggagaggaaatagagggctttcgcctcagt
gcccactgttcctgtgacagcaaagataacacactccaagtggacattaacgcagggttc
agttccggccgccggggtgacctcgccaccattcatggcatgaaccggcccttcctgctc
ctcatggccaccccgctggagagggcccagcacctgcacagcccccggcaccgccgagcc
ctggacaccaactactgcttcagctccacggaaaagaactgctgcgttcggcagctctac
attgacttccgcaaggacctgggctggaagtggattcacgaacccaagggctaccacgcc
aatttctgcctggggccctgcccctacatctggagcctggacacgcagtacagcaaggtc
ctggccctgtacaaccagcacaacccgggcgcgtcggcggcgccgtgctgcgtgccgcag
gcgctggagccgctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctg
tccaacatgatcgtgcgctcctgcaagtgcagctga

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