Physeter macrocephalus (sperm whale): 102976967
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Entry
102976967 CDS
T06011
Symbol
FASN
Name
(RefSeq) fatty acid synthase
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad00061
Fatty acid biosynthesis
pcad01100
Metabolic pathways
pcad01212
Fatty acid metabolism
pcad04152
AMPK signaling pathway
pcad04910
Insulin signaling pathway
pcad04936
Alcoholic liver disease
Module
pcad_M00082
Fatty acid biosynthesis, initiation
pcad_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
102976967 (FASN)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
102976967 (FASN)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
102976967 (FASN)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
102976967 (FASN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
pcad01004
]
102976967 (FASN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pcad04147
]
102976967 (FASN)
Enzymes [BR:
pcad01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
102976967 (FASN)
Lipid biosynthesis proteins [BR:
pcad01004
]
Fatty acid synthase
Animal type
102976967 (FASN)
Exosome [BR:
pcad04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
102976967 (FASN)
Exosomal proteins of breast milk
102976967 (FASN)
Exosomal proteins of colorectal cancer cells
102976967 (FASN)
Exosomal proteins of bladder cancer cells
102976967 (FASN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
Thioesterase
KR
Ketoacyl-synt_C
KAsynt_C_assoc
FAS_pseudo-KR
ADH_zinc_N_2
ADH_zinc_N
PKS_DH_N
Methyltransf_12
PP-binding
adh_short
Methyltransf_23
Methyltransf_31
PS-DH
Methyltransf_11
DUF7080
Thiolase_N
ACP_syn_III
Motif
Other DBs
NCBI-GeneID:
102976967
NCBI-ProteinID:
XP_023985886
Ensembl:
ENSPCTG00005018083
UniProt:
A0A2Y9T899
LinkDB
All DBs
Position
14:122838598..122857420
Genome browser
AA seq
2515 aa
AA seq
DB search
MEEVVIAGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPRRLGKLKDLSRF
DASFFGVHPKQANTMDPQLRLLLEVTYEAIVDGGINPASLRGTNTGVWVGVSSSEASEAL
SRDPETLMGYSMVGCQRAMMANRLSFFFDFKGPSVALDTACSSSLLALQSAYQAIRSGEC
PAAVVGGINILLKPNTSVQFMKLGMLSPEGSCKSFDAAGDGYCRAEAVVAVLLTKKSLAR
RVYATILNAGTNTDGFKEQGVTFPSGEVQEQLIRSLYKSAGLTPESLEYIEAHGTGTKVG
DPQELNSITRALCATRQDPLLIGSTKSNMGHAEPASGLAALVKVLLSLEHGVWAPNLHFH
SPNPKIPALQDGQLQVVDRPLPVLGGNVGINSFGFGGSNVHVILRPNSQPPPPPAPHSAL
PRLLRASGRTLEAVQGLLEQGLQHSQDLAFVSMLNDIAAAPTAAMPFRGYAVLGGQGGDQ
EVHQVPAGKRPLWFICSGMGAQWRGMGLSLMRLGSFRDSILRSDEAVKPLGLQVSDLLMS
TDEATFDDTVQSFVSLTAIQIALIDLLTSMGLRPDGIIGHSLGEVACGYADGCLSQEEAV
LAAYWRAQCIKEANIPPGAMAAVGLSWEECKRRCPPGIVPACHNSEDSVTISGPQAAMSE
FVQQLKQEGVFAKEVRTGGIAFHSYFMDSIAPALLQALKKVIREPRPRSMCWLSTSIPEA
QWQGRLARTFSAEYNVNNLVSPVLFQEALRHVPEHAVVLEIAPHALLQAILKRGLKSSCT
VIPLMKKDHRDNLEFFLGNVGRLHLMGIDINPNGLFPPVEFPAPRGTPLISPHIKWDHSQ
TWDVPAVEDFPSGSSSSSVTVYKIDASPETPDHYLLDHCIDGRVIFPATGYLFLVWKTLA
RALDQNMEQVPVVFEDVTLHQATILPKTGTVPLEVRLLEASCTFEVSENGNLIVSGQIHQ
WKDPDPRLFDNQYGTAPTPVDPTAAFHLSQGDVYKELRLRGYNYGPHFQGILEANLEGNT
GRLLWKDNWVTFLDTMLQMSLLVPGHRNLCLPTRITAIHIDPTTHRQKLHALQGETQVAD
VVVNRCLNSIVAGSVHISRLHASVAPRRQQEQLAPILEKFCFTPHVESGCLAGSLALQEE
LQLCRGLAQALQMKVAQQGMKMVVPGLESAQAPREAPQQGLPRLLATACQLQLNGNLQQE
LGQVLAQERPLLCDDPLLSGLLDSPALKACVDTALENTASLRMKVVEVLAGDGRLYSRIP
ALLNTQPLMQLDYIATDRHPQALEAAQAKLQQLDLTQGQWDPVDPAPSSLGRADLLVCNC
ALATLGDPATAVGNMAATLKEGGFLLLHTLLGGYSLGETVAFLTCSEPHQGGQHLLSQDE
WESLFTGASLHLVALKRSFYGSVLFLCRRLAPQDSPVFLSVEDASFGWVDSLKNILADSS
SRPVWLMAVGCTTSGVVGMVNCLRKEPGGHQIRCVLVSNLSSASPIPEMNPNSLELQKVL
QGDLVMNVYRDGAWGAFRHFPLEKDRPEEQTEHAFVNILTRGDLSSIRWVCSPLRHAQPT
GPGVQFCTIYYASLNFRDVMLATGKLSPDAIPGKWVARDCMLGMEFSGRDARGKRVMGLV
PAEGLATSILVSQDFLWDVPSNWTLEEAASVPVVYTTAYYALVVRGRMQPGETVLIHSGS
GGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLNEASFANSRDTSFEQHVLWYTA
GKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLKNVTFHGILLD
AIFDEDSATWREVSALLQAGIRDGVVQPLKRTVFPKTQVEDAFRYMAQGKHIGKVVLQVR
EEEQEAVLRGTKPTLTAALSKTYCPAHKTYIITGGLGGFGLELSQWLMLRGAQKLVLTSR
SGIRTGYQARQVREWRRQGVQVLVSTSNVSSLDGARSLITEATQLGPVGGVFNLAMVLRD
AMLENQTPEFFQDVNKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNASQTNYGFA
NSAMERICEKRRHDGLPGLAVQWGAIGDVGVVLETMGNNDIVIGGTLPQRIISCMEVLDL
FLNQPHPVLSSFVLAEKKAAAHGDGSSQQDLVKAVAHILGIRDLATVNLDSSLADLGLDS
LMGVEVRQMLEREHDRVLSMREIQQLTLRKLQELSSQAGTADELVAPTPKEDSPARQQAQ
LNLSTLLVNPEGPTLTPLNSVQSSERPLFLVHPIEGSITVFHSLAAKLSIPTYGLQCTGA
APLDSIQSLAAYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAQQSAGPTNNSLFL
FDGSHTYVLAYTQSYRAKMTPGCEAEAEAEAMCFFVQQFTDAEHGRVLEALLPLEGLEER
VAAAVELIAQSHAGLDRHAVRFAARSFYQKLRAAEKYTPQATYHGNVTLLRAKTGGTYGE
DLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESILSIIHSSLAEPRVSVREG
NT seq
7548 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggtggtgatcgctggcatgtccgggaagctgcctgagtcggagaacttggag
gagttctgggccaatctcatcggcggtgtggacatggtgacggatgatgacaggcggtgg
aaggcaggactgtatggcctgccccggcggttaggcaagctgaaggacctgtcccggttt
gacgcctccttcttcggggtccaccccaagcaggcaaacacaatggatccccagctgcgc
ttgcttctggaggtcacctacgaggccattgtggacggaggcatcaacccagcttccctt
cgtgggacgaacaccggtgtctgggtgggtgtgagcagctctgaggcctcagaggctctg
agtcgagaccctgaaaccctcatgggctacagtatggtgggctgccagcgtgccatgatg
gccaaccgcctctccttcttcttcgacttcaaagggcccagcgttgccctggacacagcc
tgctcctccagcctgctggccctgcagagcgcctaccaggccatccgcagtggggagtgc
cccgcggccgttgtgggtggcatcaacatcctgctgaagcccaacacctcggtgcagttc
atgaagttgggcatgctcagccctgagggctcctgcaaatccttcgatgcagcaggggat
ggctactgccgagcagaggctgtggtggccgtcttgctgaccaagaagtccctggcccga
cgggtgtatgccaccatcctcaatgccggcaccaacactgatggcttcaaagagcaaggc
gtcaccttcccctctggagaggtgcaggagcagctcatccgctccctgtacaagtcggcc
gggctgacccccgagtccctggagtatatcgaagcccatggcaccggcaccaaggtgggc
gacccccaggagctgaacagcatcacgcgggccctgtgtgccacccgccaggaccccctg
ctgatcgggtccaccaagtcaaacatggggcacgcggagcccgcctcggggctcgcagca
ctggtcaaggtgctgctgtccctggagcacggggtctgggcccccaacctgcacttccac
agcccaaaccccaagatcccagcgctgcaagacgggcagctgcaggtagtggaccggcct
ttgcccgttctcgggggcaatgtgggcatcaactccttcggcttcggcggctccaacgtg
catgtcatcctccggcccaactcccagccgcccccgccgcctgccccgcactctgccctg
ccccgtctgctgcgggccagcgggcgcacgcttgaggctgtgcagggcctgctggagcag
ggcctccagcacagccaggacctggccttcgtgagcatgctcaacgacatcgcggccgcc
cccacggccgccatgccctttcgtggctacgctgtgctgggcggccagggcggcgaccag
gaggtgcaccaggtgccagctggcaagcgcccgctctggttcatctgctccgggatgggc
gcacagtggcgcgggatggggctgagcctcatgcgcctgggcagcttccgcgactccatc
ctgcgctcagacgaggccgtgaagcctttgggactgcaagtgtcggacctgttgatgagc
acagatgaggccacctttgatgacaccgtccagtccttcgtgagcctcactgccatccag
attgccctcatagacctgctgacctccatgggcctgcgacctgacggcatcattgggcac
tccctgggcgaggtggcctgcggctacgccgacggctgcctctctcaggaggaggctgtc
ctcgctgcctactggagggcccagtgcatcaaggaggccaacatcccacccggggccatg
gcagctgtgggcttgtcctgggaagagtgtaagcggcgctgcccccctggtatcgtgcct
gcctgccacaactccgaggactctgtgaccatctccggacctcaggccgcaatgtccgag
ttcgtgcagcagctgaagcaggagggtgtgtttgccaaggaggtgcggacaggtggcata
gcgttccactcctacttcatggactccatcgcccctgcgctgctgcaggcgctcaagaag
gtgatccgggagccacggccccgctccatgtgctggctcagcacctccatccccgaggcc
cagtggcagggccgcctggcccgcacgttctcagctgagtacaacgttaacaacttggtg
agccccgtgctcttccaggaggcactgaggcacgtgcccgagcacgccgtggtgctggag
atcgccccccacgccctgctgcaggccatcctgaagcgaggcctcaagtccagctgcacc
gtcatcccgctgatgaagaaggaccacagggacaacctggagttcttcctcggcaacgtg
ggcaggctccacctgatgggcattgacatcaaccccaacggtctgttcccacccgtggag
ttcccggctccccgggggacccccctcatttccccccacatcaagtgggaccacagccag
acttgggatgtgcccgccgtggaggacttccccagtggctccagcagctcctctgtcact
gtctataagatcgatgccagccctgagacccctgaccactacctgctggatcactgcatc
gatggccgcgtgatcttccccgccactggctacctattcctggtatggaagacgctggca
cgagccctggaccaaaacatggagcaggtgcctgtggtgtttgaggacgtgacgctacac
caggccaccatcctgcccaagacagggaccgtgcccctggaagtgcggcttctggaggct
tcgtgcaccttcgaggtgtctgagaacggcaacctgatcgtgagcgggcagatacaccag
tggaaggaccccgatcccaggctctttgacaaccagtatggcacggcccccacacctgta
gaccccactgctgcgttccacctgagccagggcgacgtgtacaaggagctgcggctgcgg
ggctacaactacggcccccacttccagggcatcctcgaggccaacctcgaaggtaacaca
ggccggctgctgtggaaggacaactgggtgaccttcctggacaccatgctgcagatgtcc
ctcctggtcccgggccaccgcaacctgtgcctgcccacgcgcatcaccgccatccacatc
gaccccaccacccaccggcagaagctgcacgcgctgcaaggcgagacacaagtggccgac
gtggtggtgaacaggtgtctgaacagcatagtggccggcagcgtccacatctcgaggctc
catgcctcggtggcccctcggcgacagcaggagcagctggcacccatcctggagaagttc
tgcttcacgccgcacgtggagagcgggtgcctggctgggagcctggccctgcaggaggag
ctgcagctgtgcagggggctggcacaggcactgcagatgaaggtggcccagcaggggatg
aagatggttgtgcccgggctggaaagtgcccaggctccccgggaggccccgcaacagggc
ctgcctcggctgctggccaccgcctgccaactgcaactcaatgggaacctacagcaggaa
ctgggccaggtcctggcccaggagaggcccctgctgtgtgatgaccccctgctcagcggc
ctcctcgactccccagcactcaaggcgtgcgtggacaccgccctggagaacacggccagc
ctcagaatgaaggtggtggaggtgctggctggtgacggccgactgtattcccgcatcccg
gcgctgctgaacacccagcccctgatgcagctggactacatagccactgaccgccacccc
caggccctggaggctgcccaagccaagctgcagcagctcgacctgacccagggccagtgg
gaccctgtggacccagcccccagcagcctgggcagggctgacctcctggtgtgcaactgt
gccctggccacccttggtgacccggccacggccgtcggcaacatggcggctaccctgaag
gagggaggcttcctgctgctgcacacgctgctcggaggttactccctgggggagactgtc
gcctttctcacctgctctgagccacatcaaggggggcagcacctcctgagccaggacgag
tgggagagcctatttaccggggcatccctgcacctggtggccctgaagaggtccttctac
ggctctgtgctcttcctgtgccgccggctggccccgcaggacagcccagtcttcctgtct
gtggaagatgccagcttcggatgggtcgactcactgaagaacatcctggctgactcctcc
tcccggcccgtgtggctcatggccgttggctgcaccacctcaggagtcgtgggcatggtg
aactgtctccgaaaagagcccggcgggcaccagattcggtgcgtcctggtgtccaacctc
agtagcgcgtcccccatccctgagatgaacccaaactccttggagctgcagaaggtgctg
cagggggacctggtgatgaacgtctaccgggacggggcctggggggcgttccgccacttc
ccactggaaaaggaccggccagaggagcagacagagcacgcctttgtaaacatcctcacc
cgaggggacctctcctccatccgctgggtctgctctcctctgcgccacgcccagcccact
ggccctggagtccagttctgcaccatctattatgcctccctcaacttccgagacgtcatg
ctggccacgggcaagctgtcccccgacgccatcccaggaaaatgggtcgctcgagactgc
atgctgggcatggagttctccggccgagatgccagaggcaagcgtgtgatggggctggtg
cccgccgaaggcctggccacctccattctggtgtctcaggacttcctatgggacgtgcct
tccaactggaccctggaggaggcagcttcagtgcccgtcgtctataccacagcctattac
gcgttggtagtacgtggacgcatgcagcctggggagacggtgctcatccactcgggctcg
ggcggtgtgggtcaggccgccatcgccatcgctctcagcctgggctgccgcgtcttcacc
actgtggggtcagctgaaaagcgggcatacctccaggccaggttcccacagctcaacgaa
gccagctttgccaactcccgggacacgtccttcgagcagcacgtgctttggtacacggcc
gggaagggtgttgacctcgtcctgaattccctggcggaagagaagctgcaggccagtgtg
cggtgcctggcccagcatggtcgattcctggaaattggcaaatttgacctttccaacaac
caccccctgggcatggccatcttcctgaagaacgtgactttccacgggatcctgctggac
gcaatctttgatgaagacagtgccacctggcgggaggtgtcggcgctgctgcaggcgggc
atccgggacggcgtggtgcagcccctcaagcgcaccgtgttccccaagacccaggtggag
gatgccttccgctacatggcccagggcaaacacatcggcaaagtggtcctccaggtacgc
gaggaggagcaggaggcggtgctgcgagggaccaagcccaccctgacggcggccttgtcc
aagacctactgcccagcccacaagacctacatcatcacagggggcctgggtggcttcggc
ctagagctgtcccagtggcttatgctgcgaggggcccagaagctggtgctgacctcccgc
tccgggatccgcacaggttaccaggccaggcaggtccgtgagtggagacgccagggtgtg
caggtccttgtgtccaccagcaacgtcagctcgctggatggtgcccggagccttatcact
gaggccacccagcttgggcctgtaggcggcgtcttcaacctggccatggtcctgagagac
gccatgctggagaaccagacccctgagttcttccaggacgtcaacaaacccaagtacagt
ggcaccctgaacttggacagggtgacccgggaggcatgccccgagctggactacttcgtg
gtcttctcctcggtgagctgcgggcgtggcaacgccagccagaccaactacgggttcgcc
aactccgccatggagcgcatatgtgagaagcgccggcatgacggcctcccaggcctcgcc
gtgcagtggggcgcaattggcgatgtgggcgtcgtgctggagaccatgggtaacaacgac
atagtcattggcgggacactgccccagcgcatcatctcctgcatggaggtgctggacctc
ttcctgaaccagccccaccccgtcctgagcagctttgtgctggcggagaagaaggccgca
gcccatggtgacggcagcagccagcaggacctggtgaaggctgtggctcacatcctgggc
atccgtgacttggccactgtcaacttggacagctcactggcagacctgggcctagactca
ctcatgggcgtggaggtgcgccagatgctggagcgagagcatgaccgggtgctgtccatg
cgggaaatccagcagctcacgctccggaagctgcaggaactttcctcgcaggctggcaca
gctgatgagctggtggcccccacacccaaggaggacagccctgcccggcagcaggcccag
ctgaacctgagcaccctgctggtgaaccctgagggcccgaccttgactccgctcaactct
gtgcagagctccgagcgacccctattcctagtgcaccccatcgagggctccatcacggtg
ttccacagcctggctgccaagctcagcattcccacctacggcctgcagtgcacgggagct
gcacccctggacagcatccagagcctggccgcctactacatcgagtgcatcaggcaggtg
cagccagaggggccctaccgcattgctggctactcctatggggcctgcgtggccttcgag
atgtgctcacagctgcaggcacagcagagcgccggccccacgaacaatagcctcttcctg
ttcgatggctcgcacacctacgtgctggcctacacgcagagctaccgcgccaagatgacc
cctggctgcgaggcagaggccgaggccgaggccatgtgcttcttcgtacagcagttcact
gacgcggagcacggcagggtgctggaggcgctactgcccctcgagggcctggaggagcgc
gtggcggctgccgtggagctgatcgcacagagccatgcgggcctggaccgccacgccgtc
cgcttcgcggcgcgctccttctaccagaagctgcgggcggccgagaagtacacgccgcag
gccacctaccatggcaacgtgacactgctgcgcgccaagacaggcggcacctatggcgag
gacctgggcgctgactacaacctgtcccaggtgtgcgacggcaaggtgtccgtgcatgtc
attgagggtgaccaccgcacgctgctggagggcagcggcctggaatccatcctcagcatc
atccacagctccctggccgagccacgtgtcagcgtgcgggagggctag
DBGET
integrated database retrieval system
