Physeter macrocephalus (sperm whale): 102977395
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Entry
102977395 CDS
T06011
Symbol
ALOX12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12 isoform X3
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad00590
Arachidonic acid metabolism
pcad01100
Metabolic pathways
pcad01523
Antifolate resistance
pcad04726
Serotonergic synapse
pcad04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
102977395 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
102977395 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
102977395 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102977395 (ALOX12)
Enzymes [BR:
pcad01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
102977395 (ALOX12)
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
102977395
NCBI-ProteinID:
XP_007100761
Ensembl:
ENSPCTG00005016834
UniProt:
A0A2Y9EF90
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All DBs
Position
14:complement(89486303..89502447)
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AA seq
663 aa
AA seq
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MGRYRIRVATGAALFAGSHHRVQLWLVGARGETELELQLLPARGQEEESEHDIPEDLGPL
QFVKLRKHHSLVDNAWFCDHITVQGPAAFEEATFPCYSWVQADSVLCLPEGTARLAGNNA
LDVFQKHREKELKERRQIYCWATWKEGLPLTIAAGCEDDLPANMRFHEEKRLDFEWTLKA
GTLETVLKRVYTLLGSWNRLEDFDHIFWGQKSTLSEKVRQRWQDDELFGYQFLNGTNPML
LRRCTSLPSRLVLPSGMEELRAQLEEELQDSSLFEADFILLDGIPANVIRGEKQYLAAPL
VMLKMDTSGKLLPMVIQIQPPSSSSPTPPLFLPSDPPLAWLLAKSWVRNSDFQLHQLQYH
LLNTHLLAEVIAVATMRCLPGLHPVFKLLIPHIHYTMEINTRARTQLISEGGIFEKAVST
GGGGHVHVLRRALAQLTYCSLCPPNDLAERGLLGTPGALYACDALRLWEITARYVEGIIH
LFYRGDDVVRGDAELQAWCREITEVGLCQAQNRGFPISFQSQNQLCHFLTMCVFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVQQACLQMTITWHLGRR
QPDMVPLGHHKEKYFSDPKAKSVLNQFQTDLENLEREITDRNEQLDLPYEYLKPSLIENS
VTI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatccgcgtggccaccggggccgcactcttcgccgggtcgcaccac
cgcgtgcagctgtggctggtcggggcgcgcggcgagacggagctggagctgcagctgttg
ccggcgcggggccaggaggaggagtctgagcacgacattcccgaggacttggggccactg
cagttcgtgaagctgcgcaaacaccactccctggtggacaacgcgtggttctgcgaccac
atcacggtgcagggccctgcagccttcgaggaggccaccttcccgtgctactcctgggtg
caggccgacagcgtgctgtgcctgcccgagggcaccgcccgcctggcaggaaacaacgca
ctggacgtgttccagaaacatcgagagaaggaactgaaagaaagacgtcagatatactgc
tgggccacatggaaggaagggttacccctgacaatagctgcgggctgtgaggacgatcta
cctgcaaatatgagattccacgaggagaagaggctggactttgagtggacactgaaggca
gggactctggagacggtcctcaaacgcgtttacaccctcctgggctcctggaaccgcttg
gaggattttgatcacatcttctggggccagaagagtaccctgtctgagaaggttcgccag
cgctggcaggacgatgaattgtttggctaccagttcctcaatggcaccaatcccatgctg
ttgagacgctgcacctctctgccctcccggctagtgctgccctcggggatggaggagcta
cgggcccagctggaggaagaactccaggacagttccctgtttgaggctgatttcattctc
ctggatggaattccagccaatgtgatccgaggagagaagcagtacctggctgcccccctc
gtcatgctgaagatggacaccagtgggaagctgctacccatggtcatccagatccagcct
cccagctccagctccccgaccccaccactgttcctgccctcagatcctccacttgcctgg
ctcctggcaaagtcctgggtccgaaattcagatttccaactgcaccagctccaatatcat
ctgctgaacacccacctgctggctgaggtcattgctgtggccaccatgaggtgcctcccg
gggctgcacccggtcttcaagctcctgatcccacacatccactacacgatggaaatcaac
acccgggcacggacccaactcatctcagaaggaggtatatttgaaaaggcagtgagcacc
ggtggagggggccacgtgcacgtgctccgccgggccctggctcagctgacctactgttcc
ctctgtcctcccaacgatctggctgagcgcggcctgctgggaaccccgggtgctctctat
gcctgcgatgctttacggctctgggagatcactgcccggtacgtggaggggatcatccac
cttttctaccgcggggatgacgtcgtgagaggggacgctgagctgcaggcctggtgtcgg
gagatcactgaggtggggctgtgccaggcccagaaccgaggtttccccatctccttccag
tcccagaatcaactctgccatttccttaccatgtgtgtcttcacgtgcactgctcagcat
ggggccatcaaccagggccagctggactggtatgcctgggtccctaatgccccatgcaca
atgcggatgcccccacctaccaccaaggaagatgtgacaatggccacggtgatgggctca
ctacctgatgtccaacaggcctgtcttcaaatgaccatcacgtggcatctggggcgccgc
cagccagacatggtgcctctggggcatcacaaagaaaagtatttctcagaccccaaggcc
aagtctgtactaaaccaattccaaacagatctggaaaacttggaaagggagattacagac
cggaatgagcaacttgacctgccctatgaatacctaaagcccagcctcatagagaacagc
gtcactatctga
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