Physeter macrocephalus (sperm whale): 102979922
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Entry
102979922 CDS
T06011
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad04014
Ras signaling pathway
pcad04072
Phospholipase D signaling pathway
pcad04148
Efferocytosis
pcad04360
Axon guidance
pcad04625
C-type lectin receptor signaling pathway
pcad04630
JAK-STAT signaling pathway
pcad04650
Natural killer cell mediated cytotoxicity
pcad04660
T cell receptor signaling pathway
pcad04670
Leukocyte transendothelial migration
pcad04722
Neurotrophin signaling pathway
pcad04920
Adipocytokine signaling pathway
pcad04931
Insulin resistance
pcad05168
Herpes simplex virus 1 infection
pcad05205
Proteoglycans in cancer
pcad05208
Chemical carcinogenesis - reactive oxygen species
pcad05211
Renal cell carcinoma
pcad05220
Chronic myeloid leukemia
pcad05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
102979922 (PTPN11)
04630 JAK-STAT signaling pathway
102979922 (PTPN11)
04072 Phospholipase D signaling pathway
102979922 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
102979922 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
102979922 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
102979922 (PTPN11)
04660 T cell receptor signaling pathway
102979922 (PTPN11)
04670 Leukocyte transendothelial migration
102979922 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
102979922 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
102979922 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
102979922 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
102979922 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
102979922 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102979922 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
102979922 (PTPN11)
05211 Renal cell carcinoma
102979922 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
102979922 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
102979922 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
pcad01009
]
102979922 (PTPN11)
Enzymes [BR:
pcad01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
102979922 (PTPN11)
Protein phosphatases and associated proteins [BR:
pcad01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
102979922 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
Y_phosphatase3
PTPlike_phytase
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
102979922
NCBI-ProteinID:
XP_023976875
Ensembl:
ENSPCTG00005012444
UniProt:
A0A2Y9SKK4
LinkDB
All DBs
Position
19:11220570..11303924
Genome browser
AA seq
597 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW
QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI
DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK
RKGHEYTNIKYSLTDQASGDQSPLPPCTPTPSCAEMREDNARVYENVGLMQQQKSFR
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaatatcactggcgtggaggcagaaaacctactg
ttgacaagaggagttgatggcagttttttggcaaggcccagtaaaagtaaccctggagac
tttacactttctgttagaagaaatggagctgtcacccacatcaagattcagaacactggt
gattactatgacttgtatggaggggagaagtttgccactttggctgaattggtccagtat
tacatggaacatcatgggcaattaaaagagaagaatggagatgttattgagctcaaatat
cctctgaactgtgcagatcctacctctgaaaggtggtttcatggacatctgtctgggaaa
gaagcagagaaattattaaccgagaaaggaaaacacggtagctttcttgtgcgggagagc
cagagccaccctggagattttgttctctctgtccgaaccggagatgacaaaggggagagc
aatgacggcaagtctaaagtgacccacgttatgatccgctgtcaggaactgaaatatgat
gttggtggaggagaacggtttgactctttgacagatctcgtggagcattacaagaagaat
cctatggtagaaacattgggcacagtactacaactcaagcagcccctcaacacaactcgt
atcaatgctgctgaaatagaaagtcgggttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacaggagtgcaaa
cttctctacagccgaaaagagggtcagaggcaagagaataaaaacaaaaatagatataaa
aacatcctaccctttgatcacaccagggttgtcctacacgatggtgatcccaatgagcct
gtttcagattacatcaatgcaaacattatcatgcctgaatttgaaaccaagtgcaacaac
tcaaagcccaaaaagagttacattgccacacaaggctgcctgcaaaacaccgtgaatgac
ttttggcggatggtgtttcaagagaactcccgagtgattgtcatgacaacaaaagaagtg
gagagaggaaagagtaaatgtgtcaaatactggcctgatgagtatgcgctaaaagaatac
ggggtcatgcgcgttaggaacgtcaaggaaagtgctgctcatgactatacgttaagagaa
cttaaactttcgaaggttggacaagctctactccaggggaatacggagagaacggtctgg
caataccactttcggacctggccggaccacggagtgcccagtgaccccgggggcgtgctg
gacttcctggaggaggtccaccataagcaggagagcatcatggacgcggggcctgtggtg
gttcactgcagtgctggaattggccgaacagggacgttcattgtgattgatattcttatt
gacatcatcagagagaaaggtgtcgactgtgacattgacgttcccaaaaccattcagatg
gtgcggtctcagaggtcagggatggtccagacagaagcacagtaccgattcatctatatg
gctgtccagcattatattgaaacactacagcgcaggattgaagaagagcagaaaagcaag
aggaaagggcacgaatacacaaatattaagtattccctgacggaccaggcaagtggagat
cagagtcccctcccgccttgtaccccaacgccgtcctgtgcagaaatgagagaagataat
gctagagtctatgaaaatgtgggtctgatgcagcagcagaaaagtttcagatga
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