Physeter macrocephalus (sperm whale): 102980126 Help Entry 102980126         CDS       T06011                                  Symbol IL6 Name (RefSeq) interleukin-6   KO K05405   interleukin 6 Organism pcad  Physeter macrocephalus (sperm whale) Pathway pcad01521   EGFR tyrosine kinase inhibitor resistance pcad01523   Antifolate resistance pcad04060   Cytokine-cytokine receptor interaction pcad04061   Viral protein interaction with cytokine and cytokine receptor pcad04066   HIF-1 signaling pathway pcad04068   FoxO signaling pathway pcad04151   PI3K-Akt signaling pathway pcad04218   Cellular senescence pcad04620   Toll-like receptor signaling pathway pcad04621   NOD-like receptor signaling pathway pcad04623   Cytosolic DNA-sensing pathway pcad04625   C-type lectin receptor signaling pathway pcad04630   JAK-STAT signaling pathway pcad04640   Hematopoietic cell lineage pcad04657   IL-17 signaling pathway pcad04659   Th17 cell differentiation pcad04668   TNF signaling pathway pcad04672   Intestinal immune network for IgA production pcad04931   Insulin resistance pcad04932   Non-alcoholic fatty liver disease pcad04933   AGE-RAGE signaling pathway in diabetic complications pcad04936   Alcoholic liver disease pcad05010   Alzheimer disease pcad05020   Prion disease pcad05022   Pathways of neurodegeneration - multiple diseases pcad05132   Salmonella infection pcad05133   Pertussis pcad05134   Legionellosis pcad05135   Yersinia infection pcad05142   Chagas disease pcad05143   African trypanosomiasis pcad05144   Malaria pcad05146   Amoebiasis pcad05152   Tuberculosis pcad05161   Hepatitis B pcad05162   Measles pcad05163   Human cytomegalovirus infection pcad05164   Influenza A pcad05166   Human T-cell leukemia virus 1 infection pcad05167   Kaposi sarcoma-associated herpesvirus infection pcad05168   Herpes simplex virus 1 infection pcad05169   Epstein-Barr virus infection pcad05171   Coronavirus disease - COVID-19 pcad05200   Pathways in cancer pcad05202   Transcriptional misregulation in cancer pcad05321   Inflammatory bowel disease pcad05323   Rheumatoid arthritis pcad05332   Graft-versus-host disease pcad05410   Hypertrophic cardiomyopathy pcad05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pcad00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102980126 (IL6)    04668 TNF signaling pathway     102980126 (IL6)    04066 HIF-1 signaling pathway     102980126 (IL6)    04068 FoxO signaling pathway     102980126 (IL6)    04151 PI3K-Akt signaling pathway     102980126 (IL6)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     102980126 (IL6)    04061 Viral protein interaction with cytokine and cytokine receptor     102980126 (IL6)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     102980126 (IL6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     102980126 (IL6)    04620 Toll-like receptor signaling pathway     102980126 (IL6)    04621 NOD-like receptor signaling pathway     102980126 (IL6)    04623 Cytosolic DNA-sensing pathway     102980126 (IL6)    04625 C-type lectin receptor signaling pathway     102980126 (IL6)    04659 Th17 cell differentiation     102980126 (IL6)    04657 IL-17 signaling pathway     102980126 (IL6)    04672 Intestinal immune network for IgA production     102980126 (IL6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102980126 (IL6)    05202 Transcriptional misregulation in cancer     102980126 (IL6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102980126 (IL6)    05161 Hepatitis B     102980126 (IL6)    05171 Coronavirus disease - COVID-19     102980126 (IL6)    05164 Influenza A     102980126 (IL6)    05162 Measles     102980126 (IL6)    05168 Herpes simplex virus 1 infection     102980126 (IL6)    05163 Human cytomegalovirus infection     102980126 (IL6)    05167 Kaposi sarcoma-associated herpesvirus infection     102980126 (IL6)    05169 Epstein-Barr virus infection     102980126 (IL6)   09171 Infectious disease: bacterial    05132 Salmonella infection     102980126 (IL6)    05135 Yersinia infection     102980126 (IL6)    05133 Pertussis     102980126 (IL6)    05134 Legionellosis     102980126 (IL6)    05152 Tuberculosis     102980126 (IL6)   09174 Infectious disease: parasitic    05146 Amoebiasis     102980126 (IL6)    05144 Malaria     102980126 (IL6)    05142 Chagas disease     102980126 (IL6)    05143 African trypanosomiasis     102980126 (IL6)   09163 Immune disease    05323 Rheumatoid arthritis     102980126 (IL6)    05321 Inflammatory bowel disease     102980126 (IL6)    05332 Graft-versus-host disease     102980126 (IL6)   09164 Neurodegenerative disease    05010 Alzheimer disease     102980126 (IL6)    05020 Prion disease     102980126 (IL6)    05022 Pathways of neurodegeneration - multiple diseases     102980126 (IL6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102980126 (IL6)    05410 Hypertrophic cardiomyopathy     102980126 (IL6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102980126 (IL6)    04932 Non-alcoholic fatty liver disease     102980126 (IL6)    04931 Insulin resistance     102980126 (IL6)    04933 AGE-RAGE signaling pathway in diabetic complications     102980126 (IL6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102980126 (IL6)    01523 Antifolate resistance     102980126 (IL6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:pcad04052]     102980126 (IL6) Cytokines and neuropeptides [BR:pcad04052]  Cytokines   Interleukins    102980126 (IL6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IL6 GCSF IL23 Mod_r BGLAP_C Motif Other DBs NCBI-GeneID:  102980126 NCBI-ProteinID:  XP_007102917 Ensembl:  ENSPCTG00005003017 UniProt:  A0A2Y9EHI1 LinkDB All DBs Position 5:77346230..77350301 Genome browser AA seq 237 aa AA seqDB search MRPGMSEVQSALEPTRNERELHLPSRNPAMNSLSTIAFSLGLLLVMATAFPTPGPLGEDF KDDTTSDRLLLTSPDKTEALIKYILGKISAMRKEMCEKYDKCENSKEALAENNLNLPKMA EKDGCFQSGFNQETCLMKITTGLLEYQIYLDYLQNEYEGDKGSIEAVQISIKALVQILRQ KVKNPDEVTTPDPTTNATLLNNLQSQNNDWMKNTKIILILRSLENFLQFSLRAIRIK NT seq 714 nt NT seq  +upstreamnt  +downstreamnt atgagaccggggatgtctgaggttcagtctgccctcgagcccaccaggaacgaaagagag ctccatttgccctccaggaacccagctatgaactccctctccacaatcgccttctccctg gggctgctcctggtgatggctactgctttccctaccccgggacccctgggagaagatttc aaagatgataccacttcagacagactactcctcacctctccagacaaaactgaagctctc attaagtacatcctcggcaaaatctctgcaatgagaaaggagatgtgtgagaagtatgac aagtgtgaaaacagcaaggaggcactggcagaaaacaacctgaaccttccaaaaatggca gaaaaagacggatgcttccaatctgggttcaatcaggagacctgcttgatgaaaatcacc actggtcttctggagtatcagatatacctggactacctccagaacgagtacgagggtgat aagggaagcatcgaggctgtgcagattagtatcaaagcactggtccagatcctgaggcaa aaggtaaagaatccagatgaagtaaccacccctgacccaactacaaatgccaccctgctg aataatctgcagtcacagaacaatgactggatgaagaacacaaagattatcctcatcctg cgaagccttgagaatttcctgcagttcagcctgagggctattcggataaagtag

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