KEGG   Physeter macrocephalus (sperm whale): 102982240
Entry
102982240         CDS       T06011                                 
Symbol
FGFR3
Name
(RefSeq) fibroblast growth factor receptor 3 isoform X4
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad01521  EGFR tyrosine kinase inhibitor resistance
pcad04010  MAPK signaling pathway
pcad04014  Ras signaling pathway
pcad04015  Rap1 signaling pathway
pcad04020  Calcium signaling pathway
pcad04144  Endocytosis
pcad04151  PI3K-Akt signaling pathway
pcad04550  Signaling pathways regulating pluripotency of stem cells
pcad04810  Regulation of actin cytoskeleton
pcad05200  Pathways in cancer
pcad05206  MicroRNAs in cancer
pcad05219  Bladder cancer
pcad05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102982240 (FGFR3)
   04014 Ras signaling pathway
    102982240 (FGFR3)
   04015 Rap1 signaling pathway
    102982240 (FGFR3)
   04020 Calcium signaling pathway
    102982240 (FGFR3)
   04151 PI3K-Akt signaling pathway
    102982240 (FGFR3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102982240 (FGFR3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    102982240 (FGFR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102982240 (FGFR3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102982240 (FGFR3)
   05206 MicroRNAs in cancer
    102982240 (FGFR3)
   05230 Central carbon metabolism in cancer
    102982240 (FGFR3)
  09162 Cancer: specific types
   05219 Bladder cancer
    102982240 (FGFR3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102982240 (FGFR3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcad01001]
    102982240 (FGFR3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:pcad04090]
    102982240 (FGFR3)
Enzymes [BR:pcad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102982240 (FGFR3)
Protein kinases [BR:pcad01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   102982240 (FGFR3)
CD molecules [BR:pcad04090]
 Proteins
  102982240 (FGFR3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 FGFR3_TM V-set C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 102982240
NCBI-ProteinID: XP_023975247
Ensembl: ENSPCTG00005006670
UniProt: A0A2Y9SD17
LinkDB
Position
7:complement(144831022..144847102)
AA seq 698 aa
MGAPACALAFFVAVAVVMTGAVSGSPGMEQRVVRRAAAGAPYWTRPERMDKKLLAVPAAN
TVRFRCPAAGNPTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVV
ENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKH
VEVNGSKVGPDGTPYVTVLKSWISESVEADARLRLANVSERDGGEYLCRASNFIGVAEKA
FWLRVHGPQAAEEELVEAGEAGSVYAGVLSYGVGFLLFILVVAAVTLCRLRSPPKKGLGS
PTVHKVSRFPLKRQVSLESSSSMSSNTPLVRIARLSSGEGPALANVSELELPADPKWELS
RARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEM
MKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREYLRARRPPGTDYSFDACRLPEEQ
LTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYY
KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLK
EGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSVPFE
QYSPGGQDTPSSGSSGDDSVFAHDLLPPAPPGSGGSRT
NT seq 2097 nt   +upstreamnt  +downstreamnt
atgggcgccccggcttgcgccctcgcgttctttgtggccgtggcagtcgtgatgaccggc
gccgtctccggatccccgggcatggagcagcgcgtcgtgcggagagcagcagcaggggcc
ccttactggacgcggcccgagcggatggacaagaagctgctggcggtgccggcggccaac
acggttcgcttccgctgcccagccgccggcaaccccaccccgtccatctcctggctgaag
aacggcaaggagttccgaggcgagcaccgcatcgggggcatcaagctgcggcaccagcag
tggagcctggtcatggagagcgtggtgccttcggaccgcggcaactacacgtgcgtcgtg
gagaacaagttcggcagcatccggcagacgtacaccctggacgtgctggagcgctccccg
caccggcccatcctgcaggcggggctgcccgccaaccagacggcggtgctgggcagcgac
gtggagttccactgcaaggtgtacagcgacgcgcagccccacatccagtggctcaagcac
gtggaggtgaacggcagcaaagtggggcccgacggcacgccctacgtcacggtgctcaag
tcgtggatcagtgagagtgtggaggctgacgcgcgcctccgcctggccaatgtgtccgag
cgcgacgggggcgagtacctctgtcgagcctccaatttcataggcgtggctgagaaggcc
ttttggctgcgtgttcacgggccccaagcagctgaggaggagctggtggaggctggtgag
gctggcagtgtgtacgcaggtgtcctcagctacggggtgggcttcctcctcttcatcctg
gtggtggccgctgtgaccctctgccgcctgcgcagcccccccaagaagggcctgggctcg
cccaccgtgcacaaggtctcccgcttcccgctcaagcgacaggtgtccttggagtccagc
tcgtccatgagctccaacacgccgctggtgcggatcgcccggctgtcctcgggggagggc
cccgcgctggccaacgtctcggagctcgagctgcccgccgaccccaaatgggagctgtcc
cgggcccggctgactctgggcaagcctctcggggagggctgcttcggccaggtggtcatg
gcggaggccatcggcatcgacaaggaccgggctgccaagcccgtcacggtggcggtgaag
atgctgaaagatgacgccacggacaaggacctgtcggacctggtgtccgagatggagatg
atgaagatgatcgggaaacacaagaacatcatcaacctgctgggcgcctgcacgcagggc
gggcccctgtacgtgctggtggagtacgcggccaagggcaacctgcgggagtacctgcgg
gcgcggcggcccccgggcacggactactccttcgacgcttgccggctgcccgaggagcag
ctcaccttcaaggacctggtttcctgcgcctaccaggtggcgcggggcatggagtacctc
gcctcgcagaagtgcatccacagggacctggccgcccgcaacgtgctggtgaccgaggac
aacgtgatgaagatcgcggacttcggcctggcccgcgacgtgcacaacctcgactactac
aagaagaccaccaacggccgcctgcccgtgaagtggatggcgcccgaggccttgtttgac
cgcgtctacacccaccagagtgacgtctggtccttcggggtcctgctctgggagatcttc
acgctggggggctcgccgtaccccggcatccccgtggaggagctcttcaagctgctgaag
gaaggccaccgcatggacaagccggccaactgcacgcacgacctgtacatgatcatgcgc
gagtgctggcacgccgtgccctcccagaggcccaccttcaagcagctggtggaagacctg
gaccgcgtgctcaccgttacatccaccgacgagtacctcgacctgtcggtgccctttgag
cagtactcgccgggcggccaggacacccccagctccggctcctcaggggacgactccgtg
ttcgcccatgacctgctgcccccggccccaccaggcagcgggggctcgcggacgtga

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