Physeter macrocephalus (sperm whale): 102982983
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Entry
102982983 CDS
T06011
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad04120
Ubiquitin mediated proteolysis
pcad04144
Endocytosis
pcad04330
Notch signaling pathway
pcad04668
TNF signaling pathway
pcad04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
102982983 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
102982983 (ITCH)
04668 TNF signaling pathway
102982983 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102982983 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102982983 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pcad04131
]
102982983 (ITCH)
04121 Ubiquitin system [BR:
pcad04121
]
102982983 (ITCH)
Enzymes [BR:
pcad01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
102982983 (ITCH)
Membrane trafficking [BR:
pcad04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
102982983 (ITCH)
Ubiquitin system [BR:
pcad04121
]
Ubiquitin ligases (E3)
HECT type E3
102982983 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
102982983
NCBI-ProteinID:
XP_028354239
Ensembl:
ENSPCTG00005009484
UniProt:
A0A455BYV6
LinkDB
All DBs
Position
14:22934848..23053711
Genome browser
AA seq
868 aa
AA seq
DB search
MNDAAAMYKYLFKTLLSIFGGICQEVKLLDHVVCRPVGVMSDSGSQLGSMGSLTMKSQLQ
ITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNTNSPKWKQPLTVIVTPVSKLHF
RVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTLQLVGDKEPTETIGDLSVCLDG
LQLESDVVANGETTCSESASQNDDGSRPKDETRANTNGSDHPEDAGSGENRRVNGNNSPS
LSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNSNTSEGAT
SGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQHGRVYYVDHIEKRTTWDRPEPLPP
GWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGN
QDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRNQGQLNEKPLPE
GWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQL
AMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSH
EVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLP
FYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKP
NGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLL
CGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGF
ADLMGSNGPQKFCIEKVGKENWLPRSHT
NT seq
2607 nt
NT seq
+upstream
nt +downstream
nt
atgaatgatgctgctgctatgtacaaatacctcttcaagaccctgctttccatttttggg
ggtatatgccaagaagtgaaattgctggatcatgtggtttgccgtcctgttggtgttatg
tctgacagtggatcacagcttggttcaatgggtagcctaaccatgaaatcacaacttcag
ataactgtcatttcagcgaaacttaaagaaaataaaaagaattggtttgggccaagtcct
tatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacgaac
agtcccaaatggaagcaacctcttacagttatcgtcacccctgtgagtaaattacatttt
cgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcattagat
atctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgactttacag
cttgtaggtgacaaagaaccaacagagacaataggagatttgtcagtttgtctcgatggg
ctgcagctagagtctgatgttgttgctaatggtgaaactacatgttcagaaagtgcttca
cagaatgatgatggctccagacccaaggatgaaacaagagcgaacacaaatggatcagac
caccctgaggatgcagggtctggtgaaaataggagggtcaatgggaacaattctccatca
ctctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctccacct
accccacgtagaccagcatctgtcaatggctcaccatctgccacttctgaaagtgatggc
tctagtacaggctctctgccaccaacgaatacaaattcaaatacatctgaaggagcaacg
tctggattaataattcctcttactatatctggaggttcaggccctaggccattaaatcct
gtacctcaagctccccttccacccggttgggagcagagagtggaccagcatggacgagtt
tactatgtagatcatattgaaaaaagaacaacatgggatagaccagaacctctacctcct
ggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcacaaga
acaacgacgtggcagaggccaacattggaatctgtccggaactatgaacaatggcagctc
caacgtagtcagcttcaaggagctatgcagcaatttaaccagaggttcatttatgggaat
caagacttgtttgctacatcacaaaataaagaatttgatcccctgggtcccctgccacct
ggatgggagaagagaacggacagcaatggtagagtatattttgtcaaccacaatactcgt
atcacacaatgggaagaccccagaaatcaaggtcaattaaatgaaaagcccttacctgaa
ggctgggaaatgaggttcacagtagatggaattccatattttgtggaccacaatagaaga
acaaccacctatatagatccccgcactggaaaatctgccttagacaatggaccccagata
gcctatgtacgggacttcaaggcaaaggttcagtatttccggttctggtgtcagcaactg
gccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattccttt
cagcagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgatttttcca
ggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtcacat
gaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataattactgcttg
cagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttattggc
aggtttattgctatggctctgttccatgggaaattcatagacacaggtttttctttgcca
ttctataagcgtatcttgaacaaaccagttggactcaaggatttagaatctattgatcca
gaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttggaa
atgtatttttccgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaaccc
aatggtggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggtagct
gaatggaggttgtctcgcggtgttgaagaacagacacaagctttctttgagggctttaat
gaaattcttccccagcagtatttgcagtactttgatgcaaaggaattagaggttctttta
tgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcattac
actaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaatcgataatgag
aagagaatgagacttttgcagtttgttactggaacctgccgattgcctgttggaggattt
gctgacctcatggggagcaatgggccacagaaattctgcattgaaaaagttgggaaagaa
aattggttgcctagaagtcatacctga
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