KEGG   Physeter macrocephalus (sperm whale): 102983069
Entry
102983069         CDS       T06011                                 
Symbol
TNF
Name
(RefSeq) tumor necrosis factor
  KO
K03156  tumor necrosis factor superfamily, member 2
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad01523  Antifolate resistance
pcad04010  MAPK signaling pathway
pcad04060  Cytokine-cytokine receptor interaction
pcad04061  Viral protein interaction with cytokine and cytokine receptor
pcad04064  NF-kappa B signaling pathway
pcad04071  Sphingolipid signaling pathway
pcad04150  mTOR signaling pathway
pcad04210  Apoptosis
pcad04217  Necroptosis
pcad04350  TGF-beta signaling pathway
pcad04380  Osteoclast differentiation
pcad04612  Antigen processing and presentation
pcad04620  Toll-like receptor signaling pathway
pcad04621  NOD-like receptor signaling pathway
pcad04622  RIG-I-like receptor signaling pathway
pcad04625  C-type lectin receptor signaling pathway
pcad04640  Hematopoietic cell lineage
pcad04650  Natural killer cell mediated cytotoxicity
pcad04657  IL-17 signaling pathway
pcad04660  T cell receptor signaling pathway
pcad04664  Fc epsilon RI signaling pathway
pcad04668  TNF signaling pathway
pcad04920  Adipocytokine signaling pathway
pcad04930  Type II diabetes mellitus
pcad04931  Insulin resistance
pcad04932  Non-alcoholic fatty liver disease
pcad04933  AGE-RAGE signaling pathway in diabetic complications
pcad04936  Alcoholic liver disease
pcad04940  Type I diabetes mellitus
pcad05010  Alzheimer disease
pcad05014  Amyotrophic lateral sclerosis
pcad05020  Prion disease
pcad05022  Pathways of neurodegeneration - multiple diseases
pcad05132  Salmonella infection
pcad05133  Pertussis
pcad05134  Legionellosis
pcad05135  Yersinia infection
pcad05140  Leishmaniasis
pcad05142  Chagas disease
pcad05143  African trypanosomiasis
pcad05144  Malaria
pcad05145  Toxoplasmosis
pcad05146  Amoebiasis
pcad05152  Tuberculosis
pcad05160  Hepatitis C
pcad05161  Hepatitis B
pcad05163  Human cytomegalovirus infection
pcad05164  Influenza A
pcad05165  Human papillomavirus infection
pcad05166  Human T-cell leukemia virus 1 infection
pcad05168  Herpes simplex virus 1 infection
pcad05169  Epstein-Barr virus infection
pcad05170  Human immunodeficiency virus 1 infection
pcad05171  Coronavirus disease - COVID-19
pcad05205  Proteoglycans in cancer
pcad05310  Asthma
pcad05321  Inflammatory bowel disease
pcad05322  Systemic lupus erythematosus
pcad05323  Rheumatoid arthritis
pcad05330  Allograft rejection
pcad05332  Graft-versus-host disease
pcad05410  Hypertrophic cardiomyopathy
pcad05414  Dilated cardiomyopathy
pcad05417  Lipid and atherosclerosis
pcad05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102983069 (TNF)
   04350 TGF-beta signaling pathway
    102983069 (TNF)
   04064 NF-kappa B signaling pathway
    102983069 (TNF)
   04668 TNF signaling pathway
    102983069 (TNF)
   04071 Sphingolipid signaling pathway
    102983069 (TNF)
   04150 mTOR signaling pathway
    102983069 (TNF)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    102983069 (TNF)
   04061 Viral protein interaction with cytokine and cytokine receptor
    102983069 (TNF)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    102983069 (TNF)
   04217 Necroptosis
    102983069 (TNF)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    102983069 (TNF)
   04620 Toll-like receptor signaling pathway
    102983069 (TNF)
   04621 NOD-like receptor signaling pathway
    102983069 (TNF)
   04622 RIG-I-like receptor signaling pathway
    102983069 (TNF)
   04625 C-type lectin receptor signaling pathway
    102983069 (TNF)
   04650 Natural killer cell mediated cytotoxicity
    102983069 (TNF)
   04612 Antigen processing and presentation
    102983069 (TNF)
   04660 T cell receptor signaling pathway
    102983069 (TNF)
   04657 IL-17 signaling pathway
    102983069 (TNF)
   04664 Fc epsilon RI signaling pathway
    102983069 (TNF)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    102983069 (TNF)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102983069 (TNF)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102983069 (TNF)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102983069 (TNF)
   05170 Human immunodeficiency virus 1 infection
    102983069 (TNF)
   05161 Hepatitis B
    102983069 (TNF)
   05160 Hepatitis C
    102983069 (TNF)
   05171 Coronavirus disease - COVID-19
    102983069 (TNF)
   05164 Influenza A
    102983069 (TNF)
   05168 Herpes simplex virus 1 infection
    102983069 (TNF)
   05163 Human cytomegalovirus infection
    102983069 (TNF)
   05169 Epstein-Barr virus infection
    102983069 (TNF)
   05165 Human papillomavirus infection
    102983069 (TNF)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102983069 (TNF)
   05135 Yersinia infection
    102983069 (TNF)
   05133 Pertussis
    102983069 (TNF)
   05134 Legionellosis
    102983069 (TNF)
   05152 Tuberculosis
    102983069 (TNF)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102983069 (TNF)
   05144 Malaria
    102983069 (TNF)
   05145 Toxoplasmosis
    102983069 (TNF)
   05140 Leishmaniasis
    102983069 (TNF)
   05142 Chagas disease
    102983069 (TNF)
   05143 African trypanosomiasis
    102983069 (TNF)
  09163 Immune disease
   05310 Asthma
    102983069 (TNF)
   05322 Systemic lupus erythematosus
    102983069 (TNF)
   05323 Rheumatoid arthritis
    102983069 (TNF)
   05321 Inflammatory bowel disease
    102983069 (TNF)
   05330 Allograft rejection
    102983069 (TNF)
   05332 Graft-versus-host disease
    102983069 (TNF)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102983069 (TNF)
   05014 Amyotrophic lateral sclerosis
    102983069 (TNF)
   05020 Prion disease
    102983069 (TNF)
   05022 Pathways of neurodegeneration - multiple diseases
    102983069 (TNF)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102983069 (TNF)
   05418 Fluid shear stress and atherosclerosis
    102983069 (TNF)
   05410 Hypertrophic cardiomyopathy
    102983069 (TNF)
   05414 Dilated cardiomyopathy
    102983069 (TNF)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102983069 (TNF)
   04940 Type I diabetes mellitus
    102983069 (TNF)
   04936 Alcoholic liver disease
    102983069 (TNF)
   04932 Non-alcoholic fatty liver disease
    102983069 (TNF)
   04931 Insulin resistance
    102983069 (TNF)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102983069 (TNF)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    102983069 (TNF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:pcad04052]
    102983069 (TNF)
   00536 Glycosaminoglycan binding proteins [BR:pcad00536]
    102983069 (TNF)
Cytokines and neuropeptides [BR:pcad04052]
 Cytokines
  Tumor necrosis fators
   102983069 (TNF)
Glycosaminoglycan binding proteins [BR:pcad00536]
 Heparan sulfate / Heparin
  Cytokines
   102983069 (TNF)
SSDB
Motif
Pfam: TNF
Other DBs
NCBI-GeneID: 102983069
NCBI-ProteinID: XP_007110219
Ensembl: ENSPCTG00005013376
UniProt: A0A2Y9EW81
LinkDB
Position
18:complement(85181256..85184050)
AA seq 233 aa
MSTESMIRDVELAEEALSKTAGDSQGSRRCLCLSLFSFFLVAGATMLFCLLHFGVIGPQR
EEFPTGYSIISPLAQTLRSSSKTSSNKPVAHVVANLSAQGQLRWLNTYANTLLANSVKLE
DNQLVVPTDGLYLIYSQVLFRGQGCPPTHLFLTHTISRIAVSYQTKVNLLSAIKSPCQRE
TPEGAEAKPWYEPIYQGGVFQLEKGDRLSAEINLPDYLDFAESGQVYFGIIAL
NT seq 702 nt   +upstreamnt  +downstreamnt
atgagcactgaaagcatgatccgggatgtggagctggcagaggaggcgctctccaagacg
gccggggactcccagggttccagaaggtgcttgtgtctcagcctcttctccttcttcctg
gtcgcaggagccaccatgctcttctgcctgctgcacttcggggtaatcggcccccagagg
gaagagttcccaactggctactccatcatcagccctctggctcagacactcagatcatct
tctaaaacctcaagtaacaagcccgtagcccatgttgtagccaacctcagtgctcagggg
cagctccggtggctgaacacatatgccaacaccctcctggccaacagcgtgaagctggaa
gacaaccagctggtggtgccgacagacgggctgtacctcatctactcccaggtcctcttc
aggggccaaggctgccctcccacccacttgttcctcacccacaccatcagccgcatcgct
gtctcctaccagaccaaggtcaacctcctctctgccatcaagagcccttgccagagggag
acgccagagggggctgaggccaagccctggtatgagcccatctaccagggaggggtcttc
cagctggagaagggtgatcgactcagtgctgagatcaacctgcccgactatctggacttt
gctgagtctgggcaggtctactttgggatcattgccctgtga

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