Physeter macrocephalus (sperm whale): 102984551
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Entry
102984551 CDS
T06011
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X2
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad00562
Inositol phosphate metabolism
pcad01100
Metabolic pathways
pcad01521
EGFR tyrosine kinase inhibitor resistance
pcad04068
FoxO signaling pathway
pcad04070
Phosphatidylinositol signaling system
pcad04071
Sphingolipid signaling pathway
pcad04115
p53 signaling pathway
pcad04140
Autophagy - animal
pcad04150
mTOR signaling pathway
pcad04151
PI3K-Akt signaling pathway
pcad04218
Cellular senescence
pcad04510
Focal adhesion
pcad04931
Insulin resistance
pcad05165
Human papillomavirus infection
pcad05166
Human T-cell leukemia virus 1 infection
pcad05200
Pathways in cancer
pcad05206
MicroRNAs in cancer
pcad05208
Chemical carcinogenesis - reactive oxygen species
pcad05213
Endometrial cancer
pcad05214
Glioma
pcad05215
Prostate cancer
pcad05218
Melanoma
pcad05222
Small cell lung cancer
pcad05224
Breast cancer
pcad05225
Hepatocellular carcinoma
pcad05230
Central carbon metabolism in cancer
pcad05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pcad05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
102984551 (PTEN)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
102984551 (PTEN)
04070 Phosphatidylinositol signaling system
102984551 (PTEN)
04071 Sphingolipid signaling pathway
102984551 (PTEN)
04151 PI3K-Akt signaling pathway
102984551 (PTEN)
04150 mTOR signaling pathway
102984551 (PTEN)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102984551 (PTEN)
09143 Cell growth and death
04115 p53 signaling pathway
102984551 (PTEN)
04218 Cellular senescence
102984551 (PTEN)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102984551 (PTEN)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102984551 (PTEN)
05206 MicroRNAs in cancer
102984551 (PTEN)
05208 Chemical carcinogenesis - reactive oxygen species
102984551 (PTEN)
05230 Central carbon metabolism in cancer
102984551 (PTEN)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102984551 (PTEN)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
102984551 (PTEN)
05214 Glioma
102984551 (PTEN)
05218 Melanoma
102984551 (PTEN)
05215 Prostate cancer
102984551 (PTEN)
05213 Endometrial cancer
102984551 (PTEN)
05224 Breast cancer
102984551 (PTEN)
05222 Small cell lung cancer
102984551 (PTEN)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102984551 (PTEN)
05165 Human papillomavirus infection
102984551 (PTEN)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102984551 (PTEN)
09167 Endocrine and metabolic disease
04931 Insulin resistance
102984551 (PTEN)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102984551 (PTEN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
pcad01009
]
102984551 (PTEN)
Enzymes [BR:
pcad01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
102984551 (PTEN)
3.1.3.48 protein-tyrosine-phosphatase
102984551 (PTEN)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
102984551 (PTEN)
Protein phosphatases and associated proteins [BR:
pcad01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
102984551 (PTEN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PTEN_C2
Tc-R-P
PTP-SAK
DSPc
PTP-NADK
Y_phosphatase
PTPlike_phytase
Y_phosphatase3
DUF3256
Motif
Other DBs
NCBI-GeneID:
102984551
NCBI-ProteinID:
XP_007125605
Ensembl:
ENSPCTG00005019852
UniProt:
A0A2Y9FLR7
LinkDB
All DBs
Position
20:46641588..46730083
Genome browser
AA seq
403 aa
AA seq
DB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq
1212 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatggggtttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctatgtgctgaaagacattatgataccgccaaa
tttaactgcagagttgcacagtatcctttcgaagaccataatccaccacagctagaactt
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgtagca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgcgcatatttgtta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtatattattatagctac
ctgttaaagaatcatctggattatagaccagtggcattgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcaatttgtggtctgccagcta
aaggtgaagatatattcctccaattcaggacccacacgacgggaagacaagttcatgtac
tttgagttccctcagccattgcctgtgtgtggtgacatcaaagtagagttcttccataaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaatacattcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagtatttgcagtatagagcgtgcagataatgacaaggaatatctagtactcacttta
acaaaaaatgatcttgacaaagcaaataaagacaaggccaaccgatacttttctccaaat
tttaaggtgaagctgtacttcacaaaaacagtagaggagccatcaaatccagaggctagc
agttcaacttctgtaacaccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgatccagagaatgaaccttttgatgaagatcagcatacacaaatt
acaaaagtctga
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