Physeter macrocephalus (sperm whale): 102984604
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Entry
102984604 CDS
T06011
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret isoform X2
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad04010
MAPK signaling pathway
pcad04020
Calcium signaling pathway
pcad04151
PI3K-Akt signaling pathway
pcad05200
Pathways in cancer
pcad05216
Thyroid cancer
pcad05223
Non-small cell lung cancer
pcad05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102984604 (RET)
04020 Calcium signaling pathway
102984604 (RET)
04151 PI3K-Akt signaling pathway
102984604 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102984604 (RET)
05230 Central carbon metabolism in cancer
102984604 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
102984604 (RET)
05223 Non-small cell lung cancer
102984604 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102984604 (RET)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102984604 (RET)
Protein kinases [BR:
pcad01001
]
Receptor tyrosine kinases (RTK)
RET family
102984604 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD1
RET_CLD4
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
102984604
NCBI-ProteinID:
XP_028337722
Ensembl:
ENSPCTG00005018973
UniProt:
A0A455AMB7
LinkDB
All DBs
Position
20:10739180..10806553
Genome browser
AA seq
1071 aa
AA seq
DB search
MARATAGTAGLRLLLLLPLLGEAPLGLYFARDAYWEKLYVDQPAGMPLLYVHALQDVPEE
VPSFRLGQHLYGAYRTRLHENDWVRIQEDTGLLYLNRSLDHSSWEKLSIRNGGFPLLTVY
LQVFLSPASLREGECQWPGCARVSFSIINASFPACSALKPRDLCFPETGLSFRIRENRPP
GTFHQFRLLPVQFLCPNVSAVYRLLGGESLPFGCAVDSLEVSTRWALDREQREKYELVAK
CTVRVGAREEEVMVPFPVTVYDEDDSAPSFLGGVDTASAVVEFKRKEGTVVATLRVFDAD
VVPASGELLRRYTSTLLSGDAWALQTFRVEHSPNETLAQTNGSFVRATVHDYRLVLNRSL
PISESRAVQLAVLVNDSDFQGPGEGVLLLHFNVSVVPVSLRLPSTYSFASSRRARRFAQI
GKVCVENCQEFSGIHVQYKLQLSSANCSALGMVTSAEDATGTLFVNDTEALQRPECAQLQ
YTVVAVERPTRQQAQAPLLVTLEGTYVAEEPGCPLSCAVSKRRPECEECGGLGSLTGRCE
WRQGDGKGITRNFSTCSPSIKTCPDGHCDAVESRDANICPQDCLRGGSVIGGHEPGERRG
IKAGFGICNCFPEEKKCFCEPEDSPDPLCDELCRTVIAAAVLFSFIVSVLLSTFCIHRYH
KNAHKPPIASAEMTFRRPAQAFPVSYSSSGARRPSLDSVENQVSVDAFKIPEDPKWEFPR
KNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASASELRDLLSEFNLLTQ
VSHPQVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKAGPGYVGSRDSRNSSYLDNP
EERALTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNVLVAEGRRMKISDFGLSRDVYE
EDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLF
NLLKTGYRMERPDNCSEEMYSLMLQCWKEEPDKRPVFADISKDLDKMMVKSRDYLDLAAS
TPSDSLLYDDGLSEEEMPLVDCNNAPLPRTLPSTWIENKLYGRISHAFTRF
NT seq
3216 nt
NT seq
+upstream
nt +downstream
nt
atggcgagggcgacggccggcaccgcggggctgcggttgctgctgctgctgccgctgctc
ggcgaggccccactgggactctacttcgcaagggatgcttactgggagaagctgtacgtg
gaccagccggccggcatgcccctgctctacgtccacgccctgcaggacgtccccgaggag
gtgcccagcttccgcctgggccagcacctctacggcgcctaccgcacacggctgcacgag
aacgactgggtccgtatccaggaggacacggggcttctctaccttaaccggagcctggac
cacagctcctgggagaagctcagcatccgcaacggtggcttcccgctgctcacagtctac
ctccaggtcttcctgtcgcccgcgtcccttcgtgagggcgagtgccagtggccgggctgt
gcccgagtgtccttctccatcatcaacgcctccttcccggcttgcagtgccctcaaaccc
cgggacctctgcttccccgagacgggcctgtccttccgcattcgggagaacaggcctccc
ggcaccttccaccaattccgcctgctgcctgtgcagttcctctgccccaacgtcagcgcg
gtctacaggcttctgggaggtgagagtctgcccttcggctgcgctgtggacagcctggag
gtgagcacgcgctgggccctggaccgcgaacagcgggagaagtatgagctggtggctaag
tgcacggtgcgcgtcggcgcgcgtgaggaggaggtgatggtgccctttcccgtgaccgtg
tacgacgaagacgactctgcgcccagcttcctcgggggcgtcgacaccgccagcgccgtg
gtggagttcaagcggaaggagggcactgttgtggccacactacgtgtcttcgatgcagat
gtggtgccagcatccggggagctcctgagacggtacacaagcacgctgctctccggggat
gcctgggccctccagaccttccgagtagagcactcgcccaacgagaccttggcccagacc
aacggcagctttgtgcgggcaaccgtgcatgactacaggctggttctcaaccggagcctc
cccatctcggagagccgggcggtgcagctggccgtgctggtcaacgactcggacttccag
ggcccaggggagggcgtcctcctcctccacttcaacgtgtctgtggtgcccgtcagcctg
cgcctgcccagcacctactcctttgcctcaagcaggcgggcccgccgcttcgcccagatt
gggaaagtctgtgtggaaaactgccaggagttcagtggcatccacgtgcagtacaagctt
cagctctccagcgccaactgcagcgccctggggatggtcacctcggccgaggacgccacg
gggaccctgttcgtgaacgacacggaggccctgcagcggcccgagtgtgcccagctccag
tacacggtagtggccgtcgaacggccaacccgccagcaagcccaggccccgctgctcgtc
acactggaggggacatatgtggcagaggagccaggctgccccctgtcctgcgcggtcagc
aagaggcggcctgagtgtgaggaatgcggtggcctgggctctctgacgggcaggtgcgag
tggagacagggagacggcaaagggatcaccaggaacttctccacctgctcccccagcatc
aagacctgccccgatggccactgtgacgccgtggaaagcagagacgccaacatctgcccc
caggactgcctccggggcggcagcgtcattggtgggcacgaacctggggagcgccggggg
attaaagccggcttcggtatctgcaactgcttcccggaggagaagaagtgcttctgcgag
ccggaagacagccccgacccgctgtgtgacgagctttgccgcacggtgatcgcggcagcc
gtgctcttctccttcatcgtgtccgtgctgctgtccaccttctgcatccaccgctaccac
aagaacgcccacaagccgcccatcgcctcagctgagatgaccttccgccggcctgcccag
gcctttccggtcagctactcctcatccggtgcccgccggccctctctggactccgtggag
aaccaggtctctgtggatgccttcaagatcccggaggatccaaagtgggaattccctcgg
aagaacttggttcttggaaaaactctgggagaaggagaatttggaaaagtggtcaaagca
acggccttccggctgaaaggcaaagcagggtacacgactgtggctgtaaagatgctgaaa
gagaacgcctcggcgagcgagctgcgggacctgctgtcagagtttaacctcctgacgcag
gtcagccacccgcaagtcatcaagctatacggggcctgcagccaggacgggccacttctc
ctcatcgtggagtatgccaagtacggctccctgcggggcttcctccgagagagccgcaag
gcggggcctggctacgtgggcagcagagacagccgcaactccagctacctggacaacccg
gaggagcgggccctgaccatgggcgacctcatctccttcgcctggcagatctcgcggggg
atgcagtacctggccgagatgaagctcgtccatcgggacttggcagccagaaacgtccta
gtagccgaggggcgcaggatgaagatctcggattttggtctgtcccgagatgtttatgaa
gaggattcctacgtgaagaggagcaagggtcggatcccagtcaagtggatggccattgag
tccctcttcgatcacatctacaccacccagagtgacgtgtggtccttcggtgtcctgctg
tgggagattgtgacgctggggggcaacccctaccctgggattcctccagagcggctcttc
aaccttctgaagacaggctaccggatggagaggccagacaactgcagcgaggagatgtac
agtctgatgctgcagtgctggaaggaggagccagacaagaggccagtgtttgccgacatc
agcaaagacctggataagatgatggttaagagcagagactacttggacctggccgcatcc
accccatctgattccctgctgtacgacgacggcctgtcggaggaggagatgcccctggtg
gactgtaataacgctcccctccctcgaaccctcccctccacgtggattgaaaacaaactc
tatggtagaatttcacatgcatttactagattctag
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