KEGG   Physeter macrocephalus (sperm whale): 102985760
Entry
102985760         CDS       T06011                                 
Symbol
EHHADH
Name
(RefSeq) peroxisomal bifunctional enzyme isoform X1
  KO
K07514  enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad00071  Fatty acid degradation
pcad00280  Valine, leucine and isoleucine degradation
pcad00310  Lysine degradation
pcad00380  Tryptophan metabolism
pcad00410  beta-Alanine metabolism
pcad00640  Propanoate metabolism
pcad00650  Butanoate metabolism
pcad01100  Metabolic pathways
pcad01212  Fatty acid metabolism
pcad03320  PPAR signaling pathway
pcad04146  Peroxisome
Module
pcad_M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
pcad_M00087  beta-Oxidation
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    102985760 (EHHADH)
   00650 Butanoate metabolism
    102985760 (EHHADH)
  09103 Lipid metabolism
   00071 Fatty acid degradation
    102985760 (EHHADH)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    102985760 (EHHADH)
   00310 Lysine degradation
    102985760 (EHHADH)
   00380 Tryptophan metabolism
    102985760 (EHHADH)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    102985760 (EHHADH)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    102985760 (EHHADH)
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    102985760 (EHHADH)
Enzymes [BR:pcad01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.35  3-hydroxyacyl-CoA dehydrogenase
     102985760 (EHHADH)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.17  enoyl-CoA hydratase
     102985760 (EHHADH)
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.8  Delta3-Delta2-enoyl-CoA isomerase
     102985760 (EHHADH)
SSDB
Motif
Pfam: 3HCDH_N ECH_1 3HCDH ECH_2 UDPG_MGDP_dh_N NAD_binding_2 TrkA_N F420_oxidored 2-Hacid_dh_C
Other DBs
NCBI-GeneID: 102985760
NCBI-ProteinID: XP_007119930
Ensembl: ENSPCTG00005008175
UniProt: A0A2Y9FD47
LinkDB
Position
1:complement(77954626..78016269)
AA seq 723 aa
MAEFTRLQNCLALIRLRNPPVNALSETVLRGIKEGLQKALTDHTVKAIVICGADGIFSAG
ADIRGFSADITFDLTLGSVVDEVQRNKKPVVAAIQRVALGGGLELALGCHYRIAHAEAQV
GFPEVTLGILPGARGTQLLPRLIGVPAALDLITSGRHISANEALKLGILDKIVNSDLVEE
AIKFAQRVSDQSLESRRIYNKPIQSLSNMDSIFSEALLKMRKQHPGCLSQETSVRAVQAA
VQYPYEVGIKKEEELYVYLQRSGQARALQYSFLAERTTNKWSTPSGASWKIALARPISSV
GIVGLGTMGRGIAISFAMAKIPVIAVESDKKQLETANKIITSILEKEVSKMQQSGHPWSG
PKPRLTTSMKELSGVDLVIEAVFEERNLKKQVFAELSAVCKPEAFLCTNTSALDIDEIAS
SSDRPHLVIGTHFFSPAHVMKLLEVIPSRYSSPTTIATIMNLSKKIKKIGVVVGNCFGFV
GNRMLKPYYNQTYFLLEEGSKPEEIDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLT
GPTLPPGTPSRKRGSWRYCPIPDMLCESGRFGQKTGEGWYLYDKPLGRIHKPNPWLSKFL
TQYRETYHIEPRIISRDEILERCLYSLINEAFCILGEGMVATPEHIDVVYLHGYGWPRHR
GGPMFYASTVGLPTVVEKLQKYHRQNPDIPQLEPCDYLKKLASQGNPPLKEWQSLAGPPS
SKL
NT seq 2172 nt   +upstreamnt  +downstreamnt
atggctgagtttacgcggctgcagaactgcctggcgctgatccgcctacgaaacccgcct
gtcaacgcgctcagtgagactgttctccgtggaataaaagagggtctgcagaaagctcta
acagaccatacagtaaaagccattgtgatttgtggagcagatggcatcttctctgcaggt
gctgatatccgtggcttcagtgctgatattacctttgacttgacactgggaagtgtagta
gatgaagtacagagaaacaagaagcctgtggtggcagctatccaaagggtggctttagga
gggggactggagctggccctgggctgtcactataggattgcccatgcagaggctcaagtt
ggcttcccagaagtcacactaggaatccttcctggtgcaagaggaacccagcttctcccc
agacttattggagttcctgctgcacttgacttaattacctcaggaagacatatttcagca
aatgaagctcttaagctgggtattctagataaaattgtgaactcagatctggttgaagaa
gcaatcaaatttgcccagagagtttcagatcaatctctagaatcccgtagaatctacaac
aagccaatccagagcttgtccaacatggacagcattttcagtgaagcccttctgaagatg
cggaagcagcaccctgggtgcctttctcaggagacttccgtccgtgcagtccaggccgct
gtccagtatccctatgaggtgggcatcaagaaggaagaggagctgtatgtgtaccttcag
agatcagggcaggctagagccctgcaatattctttcttggcggagaggaccacaaataag
tggtccactccctctggagcatcctggaaaatagcattggcacggcccatctcttctgtt
ggcattgtcggcttgggaacaatgggccgaggcattgccatatcttttgcaatggccaaa
atccctgtgattgctgtagaatcagacaagaagcagctagagactgcaaacaagataata
acctccatcttagaaaaggaagtgtccaaaatgcagcagagtggccacccttggtcagga
ccaaaacccaggttaactacatctatgaaagagcttagtggtgtagatttagtcattgaa
gcagtatttgaggaaaggaacctgaagaaacaggtctttgctgaactgtcagccgtgtgc
aagccagaagcatttttgtgcaccaatacttcagccctggacattgatgagattgcttct
tccagtgatcgtcctcacttggtcattggcacccacttcttctcaccagctcacgtcatg
aagttgttagaggttattcccagccgatactcttcccccactaccattgccactattatg
aatttatcaaaaaagattaaaaaaattggagtagttgtaggcaattgttttggatttgtt
gggaatcgaatgctgaagccttattataatcagacatatttcttattggaagaaggcagt
aaaccagaggagatagatcaggtgctggaagagtttggtttcaaaatgggaccttttaga
gtgtctgatcttgctgggttggatgtaggttggaaatcccgaaaagggcaaggtcttact
ggacctacattgcctccaggaactccctcccgaaagcgaggcagctggagatattgccca
attcctgatatgctctgtgaatcaggacgatttggccagaagacaggtgagggttggtac
ctttatgataagccgttgggtaggattcacaaacctaatccctggctttccaaatttctg
acacagtacagagaaacctatcacattgaaccacgtatcattagccgggatgagatcctc
gagcgctgcttatattcactcatcaatgaagcattctgcatcttgggagaagggatggtg
gctaccccagagcacattgatgttgtctatttacacgggtatggatggccaaggcacagg
ggtgggcccatgttctatgcttccacagttgggttgcccacagtggtagagaagttgcag
aaatatcacaggcagaatcctgatattccccaactggagccttgtgactatctgaaaaaa
ctggcttcccagggaaaccctcctctgaaagagtggcaaagcttggcaggaccccccagc
agtaaattgtga

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