Physeter macrocephalus (sperm whale): 102986597
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Entry
102986597 CDS
T06011
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad01524
Platinum drug resistance
pcad03440
Homologous recombination
pcad03460
Fanconi anemia pathway
pcad04120
Ubiquitin mediated proteolysis
pcad04151
PI3K-Akt signaling pathway
pcad05206
MicroRNAs in cancer
pcad05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
102986597 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
102986597 (BRCA1)
03460 Fanconi anemia pathway
102986597 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
102986597 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
102986597 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
102986597 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
102986597 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
pcad01009
]
102986597 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
pcad04121
]
102986597 (BRCA1)
03036 Chromosome and associated proteins [BR:
pcad03036
]
102986597 (BRCA1)
03400 DNA repair and recombination proteins [BR:
pcad03400
]
102986597 (BRCA1)
Enzymes [BR:
pcad01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
102986597 (BRCA1)
Protein phosphatases and associated proteins [BR:
pcad01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
102986597 (BRCA1)
Ubiquitin system [BR:
pcad04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
102986597 (BRCA1)
Multi subunit type E3
BRCC complex
102986597 (BRCA1)
Chromosome and associated proteins [BR:
pcad03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
102986597 (BRCA1)
DNA repair and recombination proteins [BR:
pcad03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
102986597 (BRCA1)
BRCA1-A complex
102986597 (BRCA1)
BRCA1-B complex
102986597 (BRCA1)
BRCA1-C complex
102986597 (BRCA1)
BRCA complex
102986597 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
102986597 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-RING_2
zf-C3HC4_4
zf-C3HC4_3
RING_XB3-XBAT31
zf-RING_5
zf-RING_6
zf-Nse
zf-ANAPC11
zf-RING_10
zf-rbx1
BRCT
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
102986597
NCBI-ProteinID:
XP_028353920
Ensembl:
ENSPCTG00005012077
UniProt:
A0A455BY27
LinkDB
All DBs
Position
14:117307538..117356878
Genome browser
AA seq
1690 aa
AA seq
DB search
MDFSADHVEEVQNVLHAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDITRRSLQESTRFSQLVEELLKIIHAFELDTGLQIANSYNFSKKKNNSPEHLKE
EVSIIHSMGYRNRTKRLRQSEPENPTLETSLSVQLPNLGIVRSLRTKQQIQPQNKSVYIE
LGSDSSEDTVNKASYFSVGDHELLEITPQGAKAEASLNPAKKAACEFSEKDITKAEHHQF
SNKDLTTTEKHETEKHPEKYQGISVSNLHVEPCGTDTHASSLQHENSSLLLTKDRMNVEK
AEFCNKSKQPVLAKSQQSRWAESKDTCNDRQTPSTEKKVVLNADPLYGRKELNKQKSACS
DSPRDSQEFPWIAVNSSIQKVNEWFSRSDEMLTSNDLRDGGFESNPEVARAVEVPQEVDG
YLGSSEKIDLMASDPHGALIRESERVHSKPVESNIEDKIFGKTYRRKASLPNLSHVAENL
IIGASTVGPQITQERPLTNKLKRKRRSTSGLHPEDFIKKVDLAVIPKTPEKIIEGTDQTE
QNGHGVNITSNGHETEMKGDCVQKEKNANLTESLEKESAFRTKAEPISSSISNMELELNI
HSSKAPKNRLGRMSSSRKIHALELVVSRNPSPPNHTELQIDSCSSTEEMKKKHSSQMPVR
CGKKLQFIGDKEPTTGAKKSNKPHEQINKRLDSDTYPELNLTNIPVFFTHCSSSNKLQEF
VNPSLQREENLGTIQVSNSTEDPKDLTLSGGKGLQIERSVESSSISLVPDTDYGTQDSIS
LLEADTLGKAKTAPNQHVSLCAAIESPKELIHGCSKDIRNDTEDFKDPLGHHVNHIQEAS
TEMEESELDTQYLQNMFKVSKRQTFALFSNPENPEKECATVCAHSGSLREQSPRVPLECR
QKEENQGKSESKIKHVWAINTTVDFPVAGQKDKPSDHAKRSPKRVTRLCQSSQFRSNKTE
LIIANKHGISQNPYLIPSLSPIRSSVKTICKKNLSEEKFAEPVMSPERAMENESIIQSTV
STISQNNIRESTFKEVSSSSTNEVGSSTNEVGSSINEVGSSGENIQAKLDRNRGPKLSAL
LRLGLMQPEVYKQSLPVSNCQLPEIKRQGENEGTLQAVNADFSPCLVSDNLEQPMGRSHA
SQVCSETSDELLNDDKIKENSNFAESDIKERSVFSKSVQKGEFRKSTGPLAHHTCLAQGH
ERGAESSEEKVSSEDEELPCFQHLFGKVTNTLSPSTRHNAVATEGLSNETEENLISLKNS
LNDCSDQVTSAKASQEHHLHEEARCSDSLFSSRCSAVEDLTANTNTQDPFLMFDPFSKQV
GHQSENQEVLSDKELVSDDDERETGLEEDNRQEEQSVDSDLDEAASEYESETSLSEDCLG
LSSQSDILTTQQRDTMQDNLLKIQQEMAELEAVLEQHGSQRSHSSPSLIADSCAPEDLLN
LEQNTTEKAVLTSEKSSEYPISQNPESLSADKFQVSPDCSTSKNKEPGMERSSPSKSQLS
DNSWYMHSLSRSLQNRNCPPQKELEFVDVEEQRLTESEAQDLMEQSHLPRQDLEGTPYLE
SGISLFSDDPESDPSEDGAPEPAHVCSMPPSASALKLPQFQVEESSGSPAAAHTTNTAGY
NVREEGVSREKPELISSTQRGNRRISMVASGLTPKEFVLVHRFARKHHVTLTNLITEETT
HVIMKTAEGS
NT seq
5073 nt
NT seq
+upstream
nt +downstream
nt
atggatttttctgcggatcacgttgaagaagtacaaaatgtccttcatgctatgcagaaa
atcttagagtgtccaatctgtctggagttgatcaaagagcctgtttccacaaagtgtgat
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctttgtgtaagaatgatataaccagaagaagcctacaagaaagtacaagatttagt
cagcttgttgaagagctactgaagatcattcatgcttttgagcttgacacaggattgcag
attgcaaacagttataacttttcaaaaaagaaaaataactctcctgagcatctaaaggaa
gaagtttctatcattcacagtatgggctaccgaaaccggaccaaaagacttcgacaaagt
gaacctgaaaatcctaccttggaaaccagtcttagtgtccagctccctaaccttggaatt
gtgagatctctgaggacaaagcagcagatacaacctcagaataagtccgtctacattgaa
ttgggatctgattcttctgaagatacagttaataaggccagttatttcagtgtaggagac
catgaattgttagaaatcacccctcaaggagccaaggctgaagccagtttgaatcctgca
aaaaaggctgcttgtgagttttctgagaaggacataacaaaggctgaacatcatcaattc
agtaataaagatttgaccaccactgagaagcatgaaactgagaagcatccagaaaagtat
cagggtatttctgtttcaaacttgcatgtggagccatgtggcacagatactcatgccagc
tcattacagcatgaaaacagcagtttattactcactaaagacagaatgaatgtagaaaag
gctgaattctgtaataaaagcaaacagcctgtcttagcaaagagccaacagagcagatgg
gctgaaagtaaggacacatgtaatgataggcagactcccagtacagagaaaaaggtagtt
ctgaatgctgatcccctatatgggagaaaagaactgaataagcagaaatctgcatgctct
gacagtcctagagattcccaagagtttccttggatagcagtgaatagtagcatacagaaa
gttaatgaatggttttccagaagtgatgaaatgttaacttctaacgacttacgtgatggg
ggatttgaatcaaaccctgaagtagctcgtgcagtggaagttccacaggaagttgatgga
tatttgggttcttcagagaaaatagacttaatggccagtgatcctcatggtgctttaata
cgtgaaagtgaaagagtccactccaaaccagtagagagtaatattgaagataaaatattt
gggaaaacctatcggaggaaggcaagcctccctaacttgagccacgtagctgaaaatcta
attataggagcatctactgtaggacctcagattacacaagagcgccccctcacaaataaa
ctaaagcgtaaaaggagaagtacatcaggccttcatcctgaggattttatcaagaaagtc
gatttggcagttattccaaagactcctgaaaaaataattgagggaactgaccaaacagag
cagaatggtcatggggtgaatattactagtaatggtcatgagactgaaatgaaaggtgat
tgtgttcagaaagagaaaaatgctaacctaacagaatcattggaaaaagaatctgctttc
agaactaaggctgaacctataagcagcagtataagcaatatggaactagaattgaatatc
catagttcaaaagcacctaaaaataggctggggaggatgtcctcttccaggaagattcat
gcacttgaactagtagtcagtagaaacccaagcccacctaatcatactgaactacaaatt
gatagttgttctagcactgaagagatgaagaaaaaacattccagccaaatgccagtcagg
tgcggcaaaaagcttcaattcattggagataaagaacctacaactggagccaagaagagt
aacaagccacatgaacaaataaataaaagacttgacagtgacacttatccagaactaaat
ttaacaaacatacctgttttttttactcactgttctagttctaataaacttcaagagttt
gttaatcctagccttcaaagagaggagaacctaggaacaattcaagtgtcgaatagtact
gaagaccccaaagatctgacattaagtggaggaaaaggtttgcaaattgaaagatctgta
gagagttccagtatttccttggtacctgatactgattatggcactcaggatagtatctca
ttactggaagctgacaccctagggaaggcaaagacagcaccaaatcaacatgtgagtctg
tgtgcagcaattgaaagccccaaggaacttatccacggttgttctaaagatattagaaac
gacacagaggactttaaggatccactgggacatcacgttaaccacattcaggaggcgagc
acagaaatggaagagagtgaacttgatacacagtatttgcagaatatgttcaaggtttca
aagcgtcagacgtttgctctgttttcaaatccagaaaatccagaaaaggaatgtgcaaca
gtctgtgcccactctgggtccttaagagaacaaagtccaagagtccctcttgaatgcaga
caaaaagaagaaaatcagggaaagagtgagtctaaaatcaagcatgtgtgggcaattaat
acaactgtggacttccctgttgctggtcaaaaagataagccgagcgatcatgccaaacgt
agccccaaaagagtaactaggctttgtcagtcatcacagttcagaagcaacaaaactgag
ctcattattgcaaataaacatgggatttcacaaaacccatatcttataccatcactttct
cccatcaggtcatctgttaaaactatatgtaagaaaaacctgtcagaggaaaagtttgcg
gaacctgtaatgtcacctgaaagagcaatggaaaacgagagcatcattcaaagtacagtg
agcacaatcagccaaaataacattcgagaaagcacttttaaagaagtcagctcaagcagt
actaatgaagtaggttccagtaccaatgaagtaggctctagtattaatgaagtaggttcc
agtggtgaaaacattcaagcaaaactagatagaaacagaggacctaaattaagtgctttg
ctcagattaggtctcatgcaacccgaagtctataagcaaagtcttcctgtaagtaactgt
caacttcctgaaataaaaaggcaaggagaaaatgaaggcacacttcaggctgttaatgca
gatttctccccatgtctagtttcagataacctagaacaacctatgggaagaagccatgct
tctcaggtttgctctgagacatctgatgagttgttaaatgatgacaaaataaaggaaaat
agcaactttgctgaaagtgacattaaggaaagatctgtttttagcaaaagtgtccaaaaa
ggagaattcagaaagagcactggccctttagcccatcatacatgtttggctcagggtcac
gaaagaggggctgagtcctcagaagagaaagtgtctagtgaggatgaagagcttccctgc
ttccaacacttatttggtaaagtaaccaatacactgtctccatctaccagacataatgct
gttgccacagagggtctatctaatgaaacagaggagaacttaatatcattgaagaatagc
ttaaatgactgcagtgaccaggtaacatcggcaaaggcatcccaggaacatcaccttcat
gaggaagcgagatgttctgatagcttattttcttcacggtgcagtgcagtggaagacttg
actgctaatacaaacacccaggatcctttcttgatgtttgatcctttttccaaacaagtg
gggcatcagtctgaaaaccaggaagttctgagtgacaaggaattggtttcagatgatgac
gaaagggaaactggcttggaagaggataatcgccaagaagagcagagtgtggattcagac
ttagatgaagcagcatccgagtatgagagcgaaacaagcctctctgaagactgtttgggg
ctgtcctcccagagcgatatcttaaccactcagcagagggataccatgcaagataacctg
ctaaagatccagcaggaaatggccgaactggaagctgtgttagagcagcacgggagccag
cgttctcacagctccccttccctcatagccgattcttgtgcccctgaggacctgctaaat
ctggaacaaaacacaacagaaaaagcagtattaacttcagagaaaagtagtgaatatcct
ataagccagaatccagaaagcctttctgctgacaagtttcaagtatctccggattgttct
accagtaaaaataaagaaccaggaatggaaaggtcttccccgtctaaatcgcagttgtca
gataatagttggtatatgcacagcctctcaaggagtcttcagaacagaaactgcccacct
caaaaggagcttgagtttgttgatgtggaggagcaacggctgactgagtctgaggcccaa
gatttaatggagcagtcgcatttgccaagacaagatctagagggaaccccttacctagaa
tctggaatcagcctcttctctgatgaccctgagtctgatccctctgaagacggagcccca
gagccagctcatgtctgcagcatgccaccctcagcctctgcactgaaattaccccaattt
caagtagaagaatcttccgggagtccggctgctgcccatactactaatactgcagggtat
aatgtgagggaagaaggtgtgagcagggagaagccagagttgatatcttcaacacaaaga
ggcaacagaagaatttctatggtggcatcaggcttgaccccaaaagaatttgtgcttgtg
cacaggtttgccagaaaacatcacgtcactttaactaatctaattactgaagagactact
catgtcattatgaaaacagctgaaggttcttga
DBGET
integrated database retrieval system
