Physeter macrocephalus (sperm whale): 102989784
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Entry
102989784 CDS
T06011
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad04010
MAPK signaling pathway
pcad04020
Calcium signaling pathway
pcad04022
cGMP-PKG signaling pathway
pcad04024
cAMP signaling pathway
pcad04260
Cardiac muscle contraction
pcad04261
Adrenergic signaling in cardiomyocytes
pcad04270
Vascular smooth muscle contraction
pcad04713
Circadian entrainment
pcad04720
Long-term potentiation
pcad04723
Retrograde endocannabinoid signaling
pcad04724
Glutamatergic synapse
pcad04725
Cholinergic synapse
pcad04726
Serotonergic synapse
pcad04727
GABAergic synapse
pcad04728
Dopaminergic synapse
pcad04742
Taste transduction
pcad04911
Insulin secretion
pcad04912
GnRH signaling pathway
pcad04921
Oxytocin signaling pathway
pcad04924
Renin secretion
pcad04925
Aldosterone synthesis and secretion
pcad04927
Cortisol synthesis and secretion
pcad04929
GnRH secretion
pcad04930
Type II diabetes mellitus
pcad04934
Cushing syndrome
pcad04935
Growth hormone synthesis, secretion and action
pcad05010
Alzheimer disease
pcad05020
Prion disease
pcad05022
Pathways of neurodegeneration - multiple diseases
pcad05031
Amphetamine addiction
pcad05207
Chemical carcinogenesis - receptor activation
pcad05410
Hypertrophic cardiomyopathy
pcad05412
Arrhythmogenic right ventricular cardiomyopathy
pcad05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102989784 (CACNA1C)
04020 Calcium signaling pathway
102989784 (CACNA1C)
04024 cAMP signaling pathway
102989784 (CACNA1C)
04022 cGMP-PKG signaling pathway
102989784 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
102989784 (CACNA1C)
04929 GnRH secretion
102989784 (CACNA1C)
04912 GnRH signaling pathway
102989784 (CACNA1C)
04921 Oxytocin signaling pathway
102989784 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
102989784 (CACNA1C)
04924 Renin secretion
102989784 (CACNA1C)
04925 Aldosterone synthesis and secretion
102989784 (CACNA1C)
04927 Cortisol synthesis and secretion
102989784 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
102989784 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
102989784 (CACNA1C)
04270 Vascular smooth muscle contraction
102989784 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
102989784 (CACNA1C)
04727 GABAergic synapse
102989784 (CACNA1C)
04725 Cholinergic synapse
102989784 (CACNA1C)
04728 Dopaminergic synapse
102989784 (CACNA1C)
04726 Serotonergic synapse
102989784 (CACNA1C)
04720 Long-term potentiation
102989784 (CACNA1C)
04723 Retrograde endocannabinoid signaling
102989784 (CACNA1C)
09157 Sensory system
04742 Taste transduction
102989784 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
102989784 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
102989784 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
102989784 (CACNA1C)
05020 Prion disease
102989784 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
102989784 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
102989784 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
102989784 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
102989784 (CACNA1C)
05414 Dilated cardiomyopathy
102989784 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
102989784 (CACNA1C)
04934 Cushing syndrome
102989784 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pcad04040
]
102989784 (CACNA1C)
Ion channels [BR:
pcad04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
102989784 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
CAC1F_C
PKD_channel
Motif
Other DBs
NCBI-GeneID:
102989784
NCBI-ProteinID:
XP_023984736
Ensembl:
ENSPCTG00005003556
UniProt:
A0A2Y9T1D3
LinkDB
All DBs
Position
6:complement(53386633..53864375)
Genome browser
AA seq
2140 aa
AA seq
DB search
MVNENTRMYIPEENHQGPSYGSPRRAHADVNANAAAGLAPEHIPTPGAALSWQAAIDAAR
RARLMGSAGDAAISTVSSTRRKRQQHGKPKKQGGALATRPPRALLCLTLGNPIRRACIGI
VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGLDEEKPRNMSMPTSETESVNTENVA
GGDIEGESCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSSIFYWLVIFLVFLNTLT
IASEHYSQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGI
LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
TASPEKKQEVMERPAVEETKEEKIELKSITADGESPPATKINMDDLQPNESEDKSSYPNP
ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPSNRFRLQCHRIVNDS
VFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH
KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYVTYKDGE
VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
EISVFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAVQHHGQSCLFKIAMNVLNMLFTG
LFTVEMILKLVAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPFMNAEEN
SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ
VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPGSS
AEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI
WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA
TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA
TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDLGPEIRRAISGDLTAEEELD
KAMKEAVSAASEDDIFRRAGGLFGNHVRCSPSASRSAFPQTFTTQRPLHISKAGAGQGDA
ESPSHEKLVDSTFTPSSYSSMGSNANINNANNTALGRCPRPAGQPGAVSLSTVEARGPPL
SPAVQVQGASWRLSSKRCPSRDSQIAMVCQEEAPRGETCDLRMDEDAEYGSEPSLISTEM
LSYQDDENRQLAPAEEDRRDIHLSPKRGFLRSASLGRRASFHLECLKRQKNPGGDISQKT
VLPLHLVHHQALAVAGLSPLLQRSHPPGALPPPQATAPAAPGPAWPPWPVPTLRLERAES
SDKLTSSFPSVHCGPWAGEPTPCGASGGIRRARPVSLTVPSPAGPRGRPFHGSASSLVEA
VLISEGLGQFAQDPRFLEAATQELADACNLTIEEMESAADNILSGGARQSPNGTLLPCAN
CRDPGPDREGGAEDAARAPSPEPRQGGGEPRDSRAFASSL
NT seq
6423 nt
NT seq
+upstream
nt +downstream
nt
atggtcaatgaaaacacgaggatgtacattccggaggaaaaccaccaaggtcccagctat
gggagcccgcggcgggcccacgccgacgtgaacgccaacgcggccgcggggctggcgcct
gagcacatccccacgccgggggccgccctgtcctggcaggcggccatcgacgcggcccgg
cgggccaggctgatgggcagcgccggcgacgccgccatctccacggtgagctccacgcgg
cggaagcggcagcagcacgggaagcccaagaagcagggcggcgcgctggccacgcgcccg
ccccgggccctgctctgcctgaccctcgggaaccccatccggagggcgtgcatcggcatc
gtcgagtggaagccgtttgaaatcattatcttactgactatttttgccaactgcgtggcc
ttagccatctatattccctttccagaggacgactccaacgccaccaactccaacctggaa
cgggtggagtatctctttctcatcatttttactgtggaagcatttttaaaagtcatagcc
tatgggctcctctttcaccccaatgcttacctccgcaacggctggaacttgctggatttt
atcattgtggtcgtcgggcttttcagtgcaatcttagagcaagcgaccaaagccgacggg
gccaacgccctgggagggaagggggctggattcgacgtgaaggcgctcagggcgttccgc
gtgctgcggcccctgcggctggtgtccggggtcccgagtctccaggtggtcctgaactcc
atcatcaaggccatggtacccctgctacacatcgccctgctcgtgctcttcgttatcatc
atctacgccatcatcgggctggagctcttcatggggaagatgcacaagacctgctacaac
caggagggcatcgcagatgtcccagcagaagacgacccctccccctgtgccctggagacg
ggccacgggcggcagtgccagaacggcacggtgtgcaagccgggctgggatgggcccaag
cacggcatcaccaacttcgacaactttgctttcgccatgctgaccgtgttccagtgcatc
accatggagggctggaccgacgtcctctactgggtcaatgatgccgtgggaagggactgg
ccctggatctattttgttacactaatcatcatagggtcattttttgtacttaacttggtt
ctcggtgtccttagcggagagttttccaaagagagggagaaggccaaggcccggggcgac
ttccagaagctgcgggagaagcagcagctagaggaggacctgaagggctacctggactgg
atcacgcaggcggaggacatcgaccctgagaacgaggacgagggcttggacgaggagaaa
ccccgaaacatgagcatgcccaccagtgagaccgagtccgtcaacaccgaaaacgtggcc
ggaggtgacatcgagggagagagctgcggggccaggctggcccacaggatctccaagtcg
aagttcagccgctactggcgccggtggaatcggttctgcaggcggaaatgccgcgcggcc
gtgaagtcgagcatcttctactggcttgtcatcttcctggttttcctcaacacgctcacc
atcgcctctgagcactacagtcagccccactggctcacggaagtccaagacacggccaac
aaggccctgctggccctgttcacggcggagatgctgctcaagatgtacagcctggggctg
caggcctacttcgtgtccctcttcaaccgcttcgactgcttcatcgtatgcggcggcatc
ctggagaccatcctggtggagaccaagatcatgtcgcccctgggcatctccgtgctgaga
tgcgtacgcctcctgaggatatttaagatcacgaggtactggaactccctgagcaacctg
gtggcgtccctgctgaactctgtgcgctccatcgcctccctgctgctgcttctcttcctc
ttcatcatcatcttctccctcctgggcatgcagctgttcggggggaagttcaacttcgat
gagatgcagacccggaggagtacgttcgataacttcccccagtccctgctcaccgtgttt
cagatcctgaccggggaggactggaattcggtgatgtatgatgggatcatggcttatggc
ggcccctcttttccagggatgttagtctgtatttacttcatcatcctcttcatctgtgga
aattatatcctactgaatgtgttcttggccattgccgtggacaacctggctgacgccgag
agcctcacctctgcccagaaggaggaggaagaagagaaggagaggaagaagctggccagg
actgccagcccagagaagaaacaagaggtgatggagaggccggccgtggaggagaccaag
gaggagaaaatcgagctgaaatccatcactgcggatggagagtccccccctgccaccaag
atcaacatggacgacctccagcccaacgagagtgaggacaagagttcctaccccaacccg
gaaaccacaggagaagaggatgaggaggagcctgagatgcccgtgggcccccgcccacgc
cccctctcggagctgcacctgaaggagaaggcagtgcccatgccagaagccagcgccttc
ttcatcttcagcccaagcaacaggttccgtctccagtgccaccgcatcgtcaacgactcc
gtcttcaccaacctgatcctcttcttcatcctgctcagcagcatctccctggctgccgag
gaccccgtccagcacacctccttcaggaaccacattctgttttattttgacattgttttc
actaccattttcaccattgaaattgctctgaagatgaccgcctacggcgccttcctgcac
aagggctccttctgccgcaactacttcaacatcctggacctgctggtggtcagcgtgtcc
ctcatctccttcggcatccagtccagtgccatcaacgtggtgaagatcttgcgagtcctg
cgggtgctcaggcccctgagggccatcaacagggccaaggggctgaagcacgtggtgcag
tgcgtgttcgtggccatccgcaccatcgggaacatcgtcatcgtcaccacgctgctccag
ttcatgttcgcctgcatcggggtccagctcttcaagggcaagctctacacctgttcggac
agttccaaacagacggaggccgaatgcaaggggaactacgtcacatacaaggacggggag
gtggatcaccccatcatccagccgcgcagctgggagaacagcaagtttgactttgacaac
gtcctggcggctatgatggccctgttcaccgtctccacctttgaggggtggccggagctg
ctgtaccgctccatcgactcccacacggaggacaagggccccatttacaactaccgcgtg
gagatctccgtcttcttcatcatctacatcatcatcatcgccttcttcatgatgaacatc
ttcgtgggcttcgtcatcgtcaccttccaggagcagggggagcaggagtacaagaactgc
gagctggacaagaaccagcggcagtgcgtggagtacgcgctcaaggcccggcccctgcgg
aggtacatccccaagaaccagcaccagtacaaggtgtggtacgtggtcaactccacctac
ttcgagtacctgatgttcgtcctcatcctgctcaacaccatctgcctggccgtgcagcac
cacggtcagagctgcctgttcaaaatcgccatgaacgtcctcaacatgctcttcaccggc
ctcttcacggtggagatgattctgaagctcgtcgccttcaagcccaagcactatttctgt
gatgcatggaacacatttgacgccttgattgttgtgggtagcattgttgatatagccatc
accgaggtaaacccagctgaacatacccaatgctctccctttatgaacgcggaggagaac
tcccgcatctccatcaccttcttccgcctcttccgggtcatgcgtctggtcaagctgctg
agccgtggggagggcatccggacgctgctgtggacgttcatcaagtccttccaggccctg
ccctacgttgccctcctgatcgtgatgctgttcttcatctacgccgtgatcggaatgcag
gtgttcgggaaaatcgccctcaatgacacgacggagatcaacaggaacaacaacttccag
accttcccccaggccgtgctgctcctgttcaggtgcgccaccggggaggcgtggcaggac
atcatgctggcctgcatgccaggcaagaagtgcgcccccgagtcggaaccgggcagcagc
gctgagggggagacgccctgcggcagcagcttcgctgtcttctacttcatcagcttctac
atgctctgcgcctttctgatcatcaacctcttcgtagccgtcatcatggacaactttgac
tacctgacgagggactggtccatcctgggtccccaccacctggacgaatttaagagaatc
tgggcggagtatgatcctgaagccaagggtcgcatcaaacacctggacgtggtgaccctg
ctccggagaattcagcccccgctgggctttgggaagctgtgccctcaccgcgtggcttgc
aaacgcctggtctccatgaacatgcccctgaacagcgacgggaccgtcatgttcaacgcc
accctgtttgccctggtccggacggccctgaggatcaaaacggaagggaacctggaacag
gccaacgaggagctgcgggccatcatcaagaagatctggaagcggaccagcatgaagctg
ctggaccaggtggtgccgcctgcgggagatgatgaggtcacggtgggcaagttttacgct
actttcctgatccaagagtatttccggaaattcaagaagcgcaaagagcagggcctggtg
ggcaagccctcccagaggaacgccctgtccctgcaggctggtctgcgcaccctgcatgac
ctcgggcccgagatccgccgggccatctccggggacctgaccgccgaggaggagctggac
aaggccatgaaggaggctgtgtccgcggcctcggaagacgacatcttcaggagggccggc
ggccttttcggcaaccacgtgcgctgctcccccagcgccagccggagtgccttcccccag
accttcaccacccagcgtcctctgcacatcagcaaggcgggcgccggccagggtgacgcg
gagtcgccctcccacgagaaactggtggactccaccttcacgcccagcagctactcgtcc
atgggttccaacgccaacatcaacaacgccaacaacaccgccctgggccgctgcccccgc
cctgccggccagcccggcgctgtcagcctcagcaccgtggaggcccgtgggccccccttg
tcccccgctgtccaggtgcagggggcctcgtggaggctcagctccaagaggtgcccctcc
cgggacagccagatagccatggtgtgtcaggaggaggcccctcggggcgagacttgtgac
ctgaggatggatgaggacgccgagtacggcagcgagcccagcctgatctccacggagatg
ctctcctaccaggacgacgagaatcggcagctggcgcccgccgaggaggacaggagagac
atccatctgtctccgaagaggggcttcctgcgctccgcctccctaggtcgaagggcctcc
ttccacctggagtgtctgaagcgacagaagaatccagggggagacatctctcagaagaca
gtcctgcccctgcatctcgttcaccatcaggcgctggcggtggcgggcctgagccccctc
ctgcagagaagccatccccctggcgccctccccccgccgcaggccacggcccctgccgcg
cccggcccggcctggcccccgtggcctgtgcccaccctgcggctggagagggccgagtcc
agcgacaagctcaccagcagcttcccgtccgtccactgcggcccctgggccggggagccc
acgccctgtggggccagcggcggcatccggagggcgcggcccgtgtccctcaccgtgccc
agcccggcggggccccggggccggcccttccacggcagcgccagcagcctggtggaggcg
gtcttgatctcggaaggactggggcagtttgctcaggatcccaggttcctcgaggccgcc
acccaggagctggccgacgcctgcaacctgaccatcgaggagatggagagcgcggccgac
aacatcctcagcgggggtgcccggcagagccccaacggtaccctgctcccgtgtgcaaac
tgcagggacccggggccagaccgagaggggggcgcggaggacgcggcccgggcgcccagc
cccgagccccgccagggcggaggggagccccgggacagcagggccttcgccagcagcctg
tag
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integrated database retrieval system
