Physeter macrocephalus (sperm whale): 102990026 Help Entry 102990026         CDS       T06011                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism pcad  Physeter macrocephalus (sperm whale) Pathway pcad04062   Chemokine signaling pathway pcad04151   PI3K-Akt signaling pathway pcad04217   Necroptosis pcad04550   Signaling pathways regulating pluripotency of stem cells pcad04630   JAK-STAT signaling pathway pcad04658   Th1 and Th2 cell differentiation pcad04659   Th17 cell differentiation pcad05161   Hepatitis B pcad05162   Measles pcad05166   Human T-cell leukemia virus 1 infection pcad05169   Epstein-Barr virus infection pcad05200   Pathways in cancer pcad05203   Viral carcinogenesis pcad05223   Non-small cell lung cancer pcad05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:pcad00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102990026 (JAK3)    04151 PI3K-Akt signaling pathway     102990026 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     102990026 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     102990026 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     102990026 (JAK3)    04659 Th17 cell differentiation     102990026 (JAK3)    04062 Chemokine signaling pathway     102990026 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102990026 (JAK3)    05203 Viral carcinogenesis     102990026 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     102990026 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102990026 (JAK3)    05161 Hepatitis B     102990026 (JAK3)    05162 Measles     102990026 (JAK3)    05169 Epstein-Barr virus infection     102990026 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     102990026 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pcad01001]     102990026 (JAK3) Enzymes [BR:pcad01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102990026 (JAK3) Protein kinases [BR:pcad01001]  Non-receptor tyrosine kinases   JAK family [OT]    102990026 (JAK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 SH2_1 FERM_F1 Jak1_Phl ABC1 SH2 FERM_C_FAK1 Haspin_kinase Motif Other DBs NCBI-GeneID:  102990026 NCBI-ProteinID:  XP_023990249 Ensembl:  ENSPCTG00005021717 UniProt:  A0A2Y9F7X6 LinkDB All DBs Position Unknown AA seq 1104 aa AA seqDB search MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQCLSFSFGDHSAEELCVWAAKA CGILPVYHSLFALALEDLSCWFPPSHIFSVEDAGTQVLVYRLRFYFPNWFGLEKCHRFGL RKNLASAILDLPVLEHLFAQHRNDLVSGRLPMGLSLKEQGECLSLAVLDLAQMALDQGQR PEELLKTISYKVCLPPGLRDLIQGLSFVTRRRIRRTVRRALRRLAACQTDKHSLMAKYIM DLERLDPDRATETFRVGLPGAAGGQDAQGQLRVAGGSGIAWSPGEHEVLQPFCDFPEIVD ISIKQAPRIGPAGEHRLVTITRTDNQILEAEFPGLPAALSFVALVDGYFRLTTDSGHYFC KEVAPPRLLEQVAEQCHGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDSYLLTVCVATP LGPDYKGCLIRCDPTGTFSLAGLGHPHSSLRELLAAYWDGGLHVDGVELNLTFCCTPRPK EKSNLIVVRRDCNPPTSSPVQPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR HEVVDGEARETEVLLKVMDAKHKNCMESFLEAATLMSQVSYQHLVLLHGVCMAGDSIMVQ EFVYLGALDTYLRKCGQLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGT DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS GVTMPISTLDPAKKLQFYQERQQLPAPKWMELALLIQQCMAYEPGQRPSFRAVIRDLNSL ITSDYELLSDPTPGALVPHDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR YDPLGDNTGALVAVKQLQHSGPEQQRDFQREIQILKALHSDFIVKYRGVSYGPGRLSLRL VMEYLPSGCLRDFLQRYRARLDAGRLLLYASQICKGMEYLGSRRCVHRDLAARNILVESE THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL FTYSDKSCSPSAEFLRMMGCARDVPALCRLLELLADGQRLPAPPACPGEVHELMKLCWAP SPQDRPPFSTLGPQLDALWSGSQG NT seq 3315 nt NT seq  +upstreamnt  +downstreamnt atggcacctccaagtgaggagacgcccctgatccctcagcgctcctgcagcctctcctct tcagaggctggtgccctgcacgtgctgctgccccctcggggccctggacccccgcagtgc ctatccttctcctttggggaccactcagctgaagagctatgtgtttgggctgctaaggcc tgtggcatcctgcccgtgtaccactccctctttgctctggccttggaggacctgtcctgt tggttccccccgagccacatcttctccgtggaggacgcgggcacccaggtccttgtctac aggctccgcttttacttccccaactggtttgggctagagaagtgccaccgctttgggcta cgaaagaacttagccagtgccatccttgacctgccagtcctggagcacctctttgcccag caccgcaatgacctggtcagcggccgcctcccgatgggcctcagcctcaaggagcagggt gagtgtctcagcttggctgtgctggacctggcccagatggccctcgaccagggtcagcgg cccgaggagctgctgaagaccatcagctacaaggtctgcctgccccctggcctgcgcgac ctgatccagggcctgagcttcgtgacgcgaaggcgtatccgaaggacagtgcgccgggcc ttgcgccgcttggccgcctgccagactgataagcactcgctcatggccaagtacatcatg gacctcgagcggctggacccagacagggccaccgagaccttccgcgtgggcctccccgga gctgctggtggtcaggatgcgcaggggcagctccgcgtggctggcggcagtggcatcgcc tggagcccgggagaacacgaggtcctccagcccttctgcgactttccagaaatcgtggat atcagcatcaagcaggccccgcgcattggccccgccggggagcatcgcctggtcaccatc accaggacagacaaccagatcctggaggccgagttcccggggctgcccgcagcgttgtcc ttcgtggcgctcgtggatggctacttccggctgaccactgactccgggcactacttctgc aaggaggtggcgcccccgcggctgctggagcaggtggctgagcagtgccatggccccatc accttggattttgccatcaacaaactcaagactgggggttcacttcccggctcctacgtt ctccgccgcagtccccaggatttcgacagctacctcctaactgtctgtgtcgcgaccccc ctgggccctgattacaagggctgcctcatccggtgcgaccccacaggaaccttctccctg gctggccttggccatccccacagcagtcttcgagagctcctggcagcctattgggatggt gggttgcacgtggatggggttgagctgaacctcaccttctgctgcacccccagacccaaa gaaaagtccaatctgattgtggtccggagagattgcaacccacccacatcatcccctgtt cagccccaatcccaatgccagctgagtcagatgacatttcacaagatccctgctgacagc ctggagtggcatgagaacctgggtcacgggtcctttaccaagatttaccggggctgtcgc catgaggttgtggatggggaggcccgagagacagaggtgctgctcaaagtgatggatgcc aagcacaagaactgcatggagtcattcctggaagcagcgaccttgatgagccaagtatcg taccagcatctcgtgttgctccatggcgtgtgcatggctggagacagcataatggtgcag gaatttgtatacctgggagcgctggacacatatctgcgcaagtgtggccagctggtgccg gccagctggaagctacaggtgatcaaacagctggcttatgccctcaactatctggaagac aaaggtctccctcacggcaatgtctcagcccggaaggtgctcctggctcgggaggggact gacgggaacctgcctttcatcaagctgagtgaccccggtgtcagccccactgtgctaagc ctggagatgctcactgacaggatcccctgggtggcccctgagtgtctccaggaggcccga acacttggcttggaagctgacaagtggggctttggtgccacagtctgggaggtgttcagc ggtgtcacaatgcccatcagcaccctggatcctgccaagaagctccagttttaccaggaa cggcagcaactgcctgcacccaagtggatggagctggccctgctgatccaacagtgcatg gcctatgagccaggccagaggccctctttccgcgctgtcatccgtgacctgaacagcctc attacttcagattatgagctcctctcagaccccacacctggtgccctggtgccccatgat gggctttggaatggggcccagctctatgcctgccaggaccctaccatctttgaggagaga cacctcaagtacatctcacagctgggcaagggcaactttggcagtgtggaactgtgccgc tatgacccgctgggcgacaacacaggtgccctggtggccgtgaagcagttgcagcacagc gggccagaacagcagagggacttccagcgggagatccagatcctcaaagccctccacagt gacttcattgtcaagtaccggggtgtcagctatggcccaggccgcctgagcctgcggctg gtcatggagtacctgcccagcggctgcctgcgcgacttcctgcagcggtaccgcgcgcgc cttgacgctggccgcctgctcctctacgcctcgcaaatctgcaagggcatggagtacctg ggctcccgccgctgcgtgcaccgcgacctggcagcccgtaacatcctggtggagagcgag acgcatgtcaaaatcgctgacttcggcctcgccaagctgctgccgctcgacaaagactac tacgtggtccgcgagccaggccagagccccatcttctggtacgccccagagtccctctcg gacaatatcttctcgcgccagtcagatgtctggagcttcggggtcgtcctgtacgagctc ttcacctacagtgacaagagctgtagcccctcagccgagttcctgcggatgatgggatgt gccagagatgtgccagccctctgccgcctcctggagctgctggccgacggccagaggctg cccgcacctcctgcctgtcctggtgaggttcatgagctcatgaagctgtgctgggcccct agcccacaagaccggccaccattcagcaccctgggcccccagctggatgcactgtggagt ggaagccagggatag

DBGET integrated database retrieval system