| Entry |
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| Symbol |
LCK
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| Name |
(RefSeq) LOW QUALITY PROTEIN: tyrosine-protein kinase Lck
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| KO |
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| Organism |
pcad Physeter macrocephalus (sperm whale)
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| Pathway |
| pcad04650 | Natural killer cell mediated cytotoxicity |
| pcad05166 | Human T-cell leukemia virus 1 infection |
| pcad05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer |
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| Brite |
KEGG Orthology (KO) [BR:pcad00001]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
102992010 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102992010 (LCK)
04660 T cell receptor signaling pathway
102992010 (LCK)
04658 Th1 and Th2 cell differentiation
102992010 (LCK)
04659 Th17 cell differentiation
102992010 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
102992010 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102992010 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102992010 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
102992010 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
102992010 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:pcad01001]
102992010 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:pcad03036]
102992010 (LCK)
Enzymes [BR:pcad01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102992010 (LCK)
Protein kinases [BR:pcad01001]
Non-receptor tyrosine kinases
SRC family
102992010 (LCK)
Chromosome and associated proteins [BR:pcad03036]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
102992010 (LCK)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
572 aa
MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKPMLSIWNGSEVRDPLVTYEGSNPPASP
LQGDFNQQGLEEKSSGPLAVSLHLLTYSPPVLPPSPSVLSATMXLLNLSSQPIPGRFSLT
PPVFTDNLVIALHSYEPSHDGDLGFEKGEQLRILEQNGEWWKAQSVTTGQEGYIPFNFVA
RANSLEPEPWFFKTLSRKDAERQLLAPGNTHGSFLIRESESTTGSFSLSVRDFDQTQGEV
VKHYKIRNLDKGGFYISPRITFPGLHELVRHYMNSSDGLCTRLSRPCQTQKPQKPWWEDE
WEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQH
QRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTSVGIKLTINKLLDMAAQIAEGMAFIEE
QNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTF
TIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLEQGYRMVRPDNCPDELYHLMMLCW
KELPEDRPTFDYLRSVLEDFFTATEGQYQPQP |
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| NT seq |
1719 nt +upstreamnt +downstreamnt
atgggctgtagctgcagctcaaaccctgaagatgactggatggaaaacatcgatgtatgt
gagaactgccattaccccatagtcccactggatggcaagcccatgctgtccatctggaat
ggctctgaagtgcgggatccactggtcacctacgagggctccaaccccccagcttctcca
ctgcaaggtgacttcaaccagcagggcctggaagagaagtccagtggacccttggctgtc
agcctccatctcctcacctactcaccacctgtccttcctccttccccctcagtcttgtcg
gctaccatgtaactcctgaacttgagctcccagcctattccaggcaggttctccctgact
ccccctgtctttacagacaacctggttatcgccttgcacagctatgagccttcccacgat
ggagacctgggcttcgagaagggtgaacagctacgtatcctggagcagaatggcgagtgg
tggaaggcgcagtccgtgaccacgggccaggaaggttacatccccttcaactttgtggcc
agagcgaacagcctggagcccgaaccctggttcttcaagaccctgagccgcaaggacgcg
gagaggcagctcttggcgcccgggaacacgcacggctccttcctgatccgagagagtgaa
agcaccacgggatctttttcactgtccgtccgggacttcgaccagacccagggagaagtg
gtgaaacattacaagatccgtaaccttgacaaaggaggcttctacatctccccccgcatc
acttttcctggcttgcatgagctggtccgccattatatgaattcttcggacgggctgtgc
acgaggttgagccgcccctgccagacccagaagccccagaagccgtggtgggaggatgag
tgggaggttcccagggagacgctgaagctggtggagcggctgggggctggccagttcgga
gaggtgtggatggggtactacaacgggcacacgaaggtggcagtgaagagcctgaagcag
ggcagcatgtcccccgatgccttcctggccgaggccaacctcatgaagcagctgcaacac
cagcggctggtccggctctacgcggtggtcacccaggagcccatctatatcatcacggaa
tacatggagaatgggagcctggtggattttctcaagacctccgtaggcatcaagctgacc
atcaacaaactcttggacatggcagcccaaattgcagagggcatggcattcattgaagag
cagaattatatccaccgtgacttgagggccgccaacatcctggtgtctgataccctgagc
tgcaagatcgcagactttggcctagcacgcctcattgaggacaatgagtacacagccagg
gagggggccaagttccccattaagtggacagcaccagaagccattaactatgggacattc
accatcaagtcggacgtgtggtctttcgggatcctgctgacggagattgtcactcacggc
cgcatcccttacccagggatgaccaatcctgaggtgattcagaacctggagcaaggctac
cgcatggtacgacctgacaactgtccagatgagttgtaccaccttatgatgctgtgctgg
aaggagctcccggaggaccggcccacctttgactacctgcgcagcgtgctggaggacttc
ttcacagccacagagggccagtaccagcctcagccttga |
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