Physeter macrocephalus (sperm whale): 102992865
Help
Entry
102992865 CDS
T06011
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad00061
Fatty acid biosynthesis
pcad00620
Pyruvate metabolism
pcad00640
Propanoate metabolism
pcad01100
Metabolic pathways
pcad04152
AMPK signaling pathway
pcad04910
Insulin signaling pathway
pcad04920
Adipocytokine signaling pathway
pcad04922
Glucagon signaling pathway
pcad04931
Insulin resistance
pcad04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
102992865 (ACACB)
00640 Propanoate metabolism
102992865 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
102992865 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
102992865 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
102992865 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
102992865 (ACACB)
04922 Glucagon signaling pathway
102992865 (ACACB)
04920 Adipocytokine signaling pathway
102992865 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
102992865 (ACACB)
04931 Insulin resistance
102992865 (ACACB)
Enzymes [BR:
pcad01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
102992865 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
102992865 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
102992865 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
ACCA_BT
Biotin_lipoyl
Biotin_carb_C
Motif
Other DBs
NCBI-GeneID:
102992865
NCBI-ProteinID:
XP_028335695
Ensembl:
ENSPCTG00005014106
UniProt:
A0A455AGT5
LinkDB
All DBs
Position
19:complement(8864050..8926714)
Genome browser
AA seq
1742 aa
AA seq
DB search
MVVALKELSIRGDFRTTVEYLTNLLETESFQNNDIDTSWLDNLIAEKVQAEKPDIMLGVV
CGALNVADSMFRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGVKYILKVARQSPTMF
VLIMNGCHIEIDAHRLNDGGLLLSYSGSSYTTYLKEEVDSYRITIGNKTCVFEKENDPTV
LRAPSAGKLIQYLVEDGGHIEAGGSYAEIEVMKMITTLNVQESGRVKYVKRPGAVLEAGC
VVARLELDDPSKVHPAEPFTGELPSQPTLPILGEKLHQVFHGVLENLRNIMKGYCLPEPI
FSIKLKDWVQKLLVTIRHPTLPLLDLQEIMTSVSGRIPAPVEKAVRRVMAQYASNITSVL
CQFPSQQIATILDCHAATLQRKADREVFFMNTQSIVQLVQKYRSGTRGYMKAVVLDLLRR
YLLVEHHFQQAHYDKCVINLREQLKPDMSQVWDCIFSHAQVAKKNQLVIMLIDELCGPDP
SLSDELTSILSELTQLSKSKHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGH
QFCPENLKKLILSETTIFDVLPTFFYHTNKVVCMASLEVYVRRGYIAYELTSLQHRQLPD
GTCVVEFQFMLPSSHPNRMAVPISITNPELLRHSTELFMDSGFSPKSQRMGAMVAFQRFE
DFTRNFDEVISCFANVPKDIPLFSKARTSLYSEDDNKSLREEPIHILNVALQYADYLEDE
KLVPIFRTFVQSKKNILVEYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPAL
AFQLELSRLRNFDITAMPCANHKMHLYLGAARVKEGAEVTDHRFFIRVIIRHSDLITKEA
SFEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVM
RYGSRLWKLRVLQAEVKINIRQTTTDRAVPIRLFITNESGYYLDISLYKEVTDPRSGNIM
FHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKMWGSPD
KYPKDILTYAELVLDPQGQLVEMNRLPGGNEVGMVAFKMRFKTLEYPEGRDVILISNDIT
FRIGSFGLGEDLLYLRASEMARAEGIPKIYLAANSGARIGLAEEIKHMFQVAWVDPEDPH
KGIKYLYLTPQDYTTISSLNSVHCKHIEEEGESRYVITDIIGKEDGLGVENLRGSGMIAG
ETSLDYDEIVTISLVTCRALGIGAYLVRLGQRVIQVENSHIILTGAMALNKVLGREVYTS
NNQLGGVQIMHYNGVSHVTVPDDFEGVCTILEWLSYMPKDNRSPVPIITPTDPIDREIEF
QPSRAPYDPRWLLAGRPHPTLKGSWQSGFFDQGSFKEIMVPWAQTVVTGRARLGGIPVGV
IAAETRTVELAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIQDFNREKLPLMIFAN
WRGFSGGMKDMYDQVLKFGAYIVDGLRKYKQPILIYIPPCAELRGGSWAVMDTSINPLCI
EIYADRESRASVLEPEGTVEIKYRKKDLVKTMRRIDPIYKKLMEQLGTSELSDKDRKELE
GQLKAREDLLLPIYHQVAVQFADLHDKPSRMLEKGAISDILDWKTARTFLYWRLRRLLLE
DQVKQEVLQACSKLSHVHVQSMLRRWFMEMEGAVKAYLWDNNQTAVQWLEQHWQAGAGLR
STIRENIEYLKRDSVLKTIRGLVQENPEVAVDSLVYICQHLSPAERAQIIHLLSTMDSPA
ST
NT seq
5229 nt
NT seq
+upstream
nt +downstream
nt
atggtggtggctttgaaggaactgtccatccggggtgacttcaggaccaccgtggaatat
ctcaccaatctcctggagaccgagagcttccagaacaacgacattgacaccagctggttg
gataatctcatcgccgagaaagtgcaggccgagaagccggatatcatgctcggggtggtg
tgcggagccttgaacgtggccgactcgatgttcaggacctgcatgacagatttcttacac
tcgctggaaaggggccaggtcctccccgcagactctctgctgaacattgtggatgtagaa
ttaatctatggaggcgttaagtacatcctcaaggtggcccggcagtctccaaccatgttc
gtcctgatcatgaatggctgtcacatcgagatcgacgcccaccggctgaacgacgggggg
ctgctgctgtcctacagtggcagcagctacaccacgtacctgaaggaggaggtcgacagt
taccgaatcaccatcggcaacaagacgtgtgtgtttgagaaggagaatgatcccacggtc
ctgagagccccttcggcggggaagctgatacagtacttggtggaggacgggggccacatc
gaggctgggggcagctatgctgagatagaggtgatgaagatgatcacgaccctgaatgtg
caggagagtggccgggtgaagtatgtcaagcgcccaggggctgtgttggaagcaggctgt
gtggtggccaggctggagctcgacgacccttctaaagtgcacccggctgagccattcacg
ggagagctcccctcccaaccaacgctgcccatcctcggagagaaactgcaccaggttttt
cacggtgtcctggaaaatctgaggaacatcatgaagggctactgtctgccggagcctatt
tttagcatcaagctgaaggactgggtgcagaagctcctggtgaccatccggcacccaacg
ctgccactgctggatctgcaggagatcatgaccagcgtgtcgggccgcatccccgccccc
gtggagaaggctgtccgcagggtgatggcccagtacgccagcaacatcacctcggtgctg
tgccagttccccagccagcagatagccaccatcctggactgccatgcggctaccctgcag
cggaaggccgatcgggaggtcttcttcatgaacacccagagcattgtgcagctggtccag
aaataccgcagtgggacccggggctacatgaaggcggtggtgttggatctcctgcgaaga
tatttactggttgagcaccatttccaacaagcccactacgacaagtgtgtgataaacctc
agggagcagctgaaaccagacatgtcccaggtgtgggactgcatcttctcccatgcgcag
gtggccaagaagaaccagctggtgatcatgttgatcgatgagctctgtggcccagaccct
tccctgtcagatgagctgacctccatcctcagcgagctcactcagctgagcaaaagcaag
cactgcaaggtggccctcagagccaggcaggtcctgattgcctcccacctcccctcctat
gagctgaggcacaaccaggtggagtccattttcctgtctgccatcgacatgtatggccac
cagttctgcccggaaaacctcaagaaattaatactctcagaaacgaccatatttgacgtc
ctgcccactttcttctatcatactaacaaagtcgtctgcatggcatccttggaggtttat
gtgcggaggggctacatcgcctatgagttaaccagcctgcagcaccggcagctcccggac
ggcacctgtgtggtggaattccagttcatgctgccctcctcccacccaaaccggatggcc
gtacccatcagcatcaccaaccctgaactgctgaggcacagcacggagctcttcatggac
agtggcttctcccccaagtcccagcggatgggggccatggttgccttccagagatttgag
gatttcaccaggaactttgatgaggtcatttcctgctttgccaacgtgcccaaggacatc
cctctcttcagcaaggcccgtacttccctgtactccgaggatgacaacaagagcctccga
gaagagccgatccacatcctgaacgtggccctccagtatgcagactacctggaggatgag
aagctggtgcctattttccgaacattcgttcagtccaagaaaaacatccttgtggagtat
ggactccgaagaattacattcctgattgctcaagagaaagaatttcccaagtttttcaca
ttcagagcaagagacgagtttgcagaagatcgcatttaccgtcacttggagccggccctg
gccttccagctggagctcagccggttgcgtaactttgacataactgccatgccctgcgcc
aaccacaagatgcatctgtacctgggcgctgccagagtgaaagagggcgccgaggtcacg
gaccacaggttcttcatccgcgtcatcatcaggcattcagacctgatcaccaaggaagcc
tccttcgagtacctgcagaacgaaggcgagcggctgcttctggaggccatggacgagctg
gaggtggcgtttaacaacaccagcgtgcgcacagactgcaatcacatcttcctcaacttc
gtgcccaccgtcatcatggacccctccaagattgaggagtcagtgcggtccatggtgatg
cgctacggcagccggttgtggaaactccgcgtgctccaggctgaggtcaagatcaacatc
cgccagaccaccaccgaccgcgccgttcccatccgcctgttcatcaccaacgagtcaggc
tactacctggacatcagcctctacaaagaagtgaccgaccccagatctggaaacatcatg
tttcactccttcggcaacaaacaagggccccagcacgggatgctgatcaatactccctac
gtcaccaaggatctgcttcaggccaagcgattccaggcccagtccctgggtaccacctat
gtgtatgacttcccggaaatgttcaggcaggctctttttaaaatgtggggctccccggac
aagtaccccaaagacatcctgacatacgccgaactagtgctggacccgcagggccagctg
gtggagatgaaccgacttcctggaggaaatgaggtgggcatggtggccttcaaaatgagg
tttaagacccttgagtacccagaagggcgcgacgtcatcctcatcagcaatgacatcacc
ttccggataggatcctttggccttggagaagaccttctgtacctgcgggcgtccgagatg
gcccgggcagagggcatccccaaaatctacctcgctgccaacagtggggcccgtatcggc
cttgcggaggagatcaaacacatgttccaggtggcttgggtggacccggaagacccccac
aagggaattaaatacctgtacctgactccccaagactacaccacaatcagctccctgaac
tccgtccattgtaaacacatcgaggaagaaggagaatccaggtatgtcatcacggatatc
attgggaaggaggatggcctgggcgtagagaatctgaggggctcaggcatgattgctggg
gagacctccctggattatgatgagattgtcaccatcagcttggtgacctgccgagccctt
gggatcggggcctacctggtgaggctgggccagcgagtgatccaggtggagaattcccac
atcatcctgacaggggcaatggctctcaacaaggtcctgggcagagaggtttacacatcc
aacaaccagctgggcggcgtgcagatcatgcattacaatggtgtctcccatgtcaccgtg
ccggatgacttcgagggtgtttgtaccatcctggagtggctgtcctatatgccaaaggat
aatcgcagcccagtcccaatcatcacacccactgaccccattgacagagagattgaattc
caaccatctcgcgcgccctatgacccccggtggttgcttgcaggaaggcctcacccaacc
ctgaagggatcctggcagagtggattcttcgaccagggcagtttcaaggaaatcatggtg
ccctgggcccagaccgtggtgacgggacgagcaaggcttggggggatccccgtcggagtg
atcgctgcagagacacggacagtggagttggctgtgcccgcagaccctgccaacctggat
tccgaggccaagataatccagcaggcaggccaggtgtggttcccagactcggcctacaag
acagcccaggccatccaggatttcaaccgggagaagttgcccctcatgatctttgccaac
tggagggggttctccggtggcatgaaagacatgtacgaccaggtgctgaagtttggagcc
tacatcgtggatggcctccggaagtacaaacagcccatcctgatctacatcccgccctgc
gcggagctccggggaggctcctgggcagtcatggacacctccatcaacccgctgtgcata
gaaatatacgcggacagagagagcagagcgagtgttctggagccagagggaacagtggag
attaagtaccggaagaaagatctggtaaagaccatgagaagaatcgacccaatttacaag
aagctcatggaacagctaggaacgtctgagctctccgacaaggaccgcaaggagctggag
ggccagctgaaggcccgggaggacctgctgctgcccatctaccaccaggtggcggtgcag
ttcgccgacctccacgacaagcccagcaggatgctggagaagggtgccatctctgacatc
ctggattggaagaccgcccgcaccttcctgtactggcgcctgcgccgcctgctgctggag
gaccaggtcaagcaggaggtcctgcaggcctgcagcaagctcagccacgtgcatgtccag
tccatgctgcgccgctggttcatggagatggagggggccgtcaaggcctacctatgggac
aacaaccagacggcggtgcagtggctggagcagcattggcaggcgggggcggggctgcgc
tccaccatccgcgagaacatagagtacttgaagcgggactctgtcctcaagaccatccga
ggcctggttcaagaaaaccccgaggtggccgtggactccctggtgtacatatgccagcac
ctcagcccggccgagcgggcccagatcattcacctcctgtccaccatggacagcccggcc
tccacctga
DBGET
integrated database retrieval system
