KEGG   Proteus columbae: F1325_18955
Entry
F1325_18955       CDS       T06419                                 
Name
(GenBank) trimethoprim-resistant dihydrofolate reductase DfrA1
  KO
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
pcol  Proteus columbae
Pathway
pcol00670  One carbon pool by folate
pcol00790  Folate biosynthesis
pcol01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:pcol00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    F1325_18955
   00670 One carbon pool by folate
    F1325_18955
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:pcol01504]
    F1325_18955
Enzymes [BR:pcol01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     F1325_18955
Antimicrobial resistance genes [BR:pcol01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    F1325_18955
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: QHN12394
UniProt: A0A6I7DCJ2
LinkDB
Position
complement(4058477..4058950)
AA seq 157 aa
MKLSLMVAISKNGVIGNGPDIPWSAKGEQLLFKAITYNQWLLVGRKTFESMGALPNRKYA
VVTRSSFTSDNENVLIFPSIKDALTNLKKITDHVIVSGGGEIYKSLIDQVDTLHISTIDI
EPEGDVYFPEIPSNFRPVFTQDFASNINYSYQIWQKG
NT seq 474 nt   +upstreamnt  +downstreamnt
gtgaaactatcactaatggtagctatatcgaagaatggagttatcgggaatggccctgat
attccatggagtgccaaaggtgaacagctcctgtttaaagctattacctataaccaatgg
ctgttggttggacgcaagacttttgaatcaatgggagcattacccaaccgaaagtatgcg
gtcgtaacacgttcaagttttacatctgacaatgagaacgtattgatctttccatcaatt
aaagatgctttaaccaacctaaagaaaataacggatcatgtcattgtttcaggtggtggg
gagatatacaaaagcctgatcgatcaagtagatacactacatatatctacaatagacatc
gagccggaaggtgatgtttactttcctgaaatccccagcaattttaggccagtttttacc
caagacttcgcctctaacataaattatagttaccaaatctggcaaaagggttaa

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