Puma concolor (puma): 112852387
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Entry
112852387 CDS
T08890
Symbol
JAK3
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine-protein kinase JAK3
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo04062
Chemokine signaling pathway
pcoo04151
PI3K-Akt signaling pathway
pcoo04217
Necroptosis
pcoo04550
Signaling pathways regulating pluripotency of stem cells
pcoo04630
JAK-STAT signaling pathway
pcoo04658
Th1 and Th2 cell differentiation
pcoo04659
Th17 cell differentiation
pcoo05161
Hepatitis B
pcoo05162
Measles
pcoo05166
Human T-cell leukemia virus 1 infection
pcoo05169
Epstein-Barr virus infection
pcoo05200
Pathways in cancer
pcoo05203
Viral carcinogenesis
pcoo05223
Non-small cell lung cancer
pcoo05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
112852387 (JAK3)
04151 PI3K-Akt signaling pathway
112852387 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
112852387 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
112852387 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
112852387 (JAK3)
04659 Th17 cell differentiation
112852387 (JAK3)
04062 Chemokine signaling pathway
112852387 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112852387 (JAK3)
05203 Viral carcinogenesis
112852387 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
112852387 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
112852387 (JAK3)
05161 Hepatitis B
112852387 (JAK3)
05162 Measles
112852387 (JAK3)
05169 Epstein-Barr virus infection
112852387 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
112852387 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcoo01001
]
112852387 (JAK3)
Enzymes [BR:
pcoo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
112852387 (JAK3)
Protein kinases [BR:
pcoo01001
]
Non-receptor tyrosine kinases
JAK family [OT]
112852387 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F1
ABC1
Kdo
Kinase-like
SH2_1
FERM_F2
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
112852387
NCBI-ProteinID:
XP_025771660
UniProt:
A0A6P6H7F4
LinkDB
All DBs
Position
Unknown
AA seq
1050 aa
AA seq
DB search
MAHPPLSPPAKKGSGSPRAAAHQDFVDGSPASRKPHAHWFVGPALNQICFFIASGSTNLT
QPRLRSQLDYNSQEPLPSEAGALHCCCXPSGPRTPQRLSFSFGDHSAEELCVWAAKASGE
SVLPVHHPFAPTRRILSHWQPPSHIFSWWEDAKQLQVLLYSLQASSPTGHFPNWFGXEKC
HRLPWKDLASHPDLPRESPSTSWASVSREQGECLSLAVLDLPRWPAEQAQQPEELLKTAA
DAGKSEDCAPGLPLRTACQADGRHSARLSTSWDLESWTRQAAESFLVSLPGXAGGQMPGL
LXVAGDSGIHWSPEDTRPPALLRIFQTSAIKQVRVGPHREHRHHRHQDDNQILPDFAINK
LHVGAPFLGMFSTGCLIRVTPTGTFSLAGLGRPHSSLRALGSLGWDAGLHGWGYSLTSCC
PRPKEKSNLIVVRRGCSTPTSSLVWPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIY
RGCRHEAVDGEARETEVLLKVMDAKHRNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDS
VMVQEFVRLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLA
REGADGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVW
EVFSGIPMPISILDPAKKLQFYEERQHLPAPKWMELATLIQQCMAYEPGQRPSFRAIIRD
LNSLITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSV
ELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQ
SLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYASQICKGMEYLGSRRCVHRDLAARNIL
VESETHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVV
LYELFTYGNKNCSPSAEFLRMMGWERDVPALCRLLELLAEGQRLPAPPACPGEVHELMKL
CWAPSPQDRPTFSALGPQLDTLWSGSRGVA
NT seq
3153 nt
NT seq
+upstream
nt +downstream
nt
atggcgcaccctccgctctcgccgccagccaagaaaggaagtggcagccctcgcgcagcc
gctcaccaggacttcgttgacggaagtcccgcctcccgcaagccgcacgcccattggttt
gtcggcccggcgctcaaccagatctgctttttcattgcctccggatccaccaacctcaca
cagccccgccttcgttcgcagctagactacaactcacaggagcctctgccttcagaggct
ggtgccctgcattgctgctgtnntccctcggggccccggaccccacaacgcctgtccttc
tcctttggggaccattcagctgaagagctatgtgtttgggctgctaaggccagtggtgag
tcggtcctgcctgtgcaccacccctttgctcccacacggaggatcctgtcccactggcaa
cctccgagccacatcttctcctggtgggaggatgcaaagcaactccaagtcctgctctac
agcctccaggcttcttccccaacaggccatttccccaactggtttgggnctgagaaatgc
caccgcttgccatggaaggacttggctagccatcctgacttgccacgggagagcccttct
accagctgggcctcagtctcaagggagcagggtgaatgtctcagcctggcagtgctggac
ctacctcgatggcctgcggagcaggctcagcagcctgaggagctgctgaagaccgctgcg
gacgccgggaagtccgaggactgtgcgccgggcctgccgctgcggaccgcctgccaggct
gatggcaggcactccgccaggctaagtacatcatgggacctggagagctggacccgccag
gccgccgagtccttcctcgtgagcctccctgggnctgctggtggtcagatgcccgggctg
ctcncagtggctggtgacagcggcatccactggagtccggaggacacgaggcctccagcc
cttctgcgaattttccagacatcagcaatcaagcaggtccgtgttggtcctcaccgggag
caccgccatcaccgccaccaggacgacaaccagatcctgcctgattttgccatcaacaag
cttcatgtcggggctcccttcctcggcatgttctctacgggctgcctcatccgtgtgacc
cctactggaaccttctccctggctggcctcggccgcccacacagcagtcttcgagctctt
ggcagcctgggttgggatgctgggctgcacggatggggctacagcctcacctcctgctgc
cccagacccaaagaaaagtccaacctgatcgtggtgcggagaggttgcagcactcccaca
tcatcccttgtttggccccaatcccagtgccagctgagtcagatgacgtttcacaagatc
cctgctgacagcctggagtggcatgagaacctgggtcatgggtccttcaccaagatttac
cgaggttgtcgccatgaggctgtggacggggaagcccgggagacagaggtgctactcaaa
gtgatggatgccaagcacagaaactgcatggagtccttcctggaagcagcgagcctgatg
agccaagtgtcgtatcagcacctcgtgttgctccacggcgtgtgcatggctggagacagt
gtcatggtgcaggaatttgtgcgcctgggagccctggatacatatctgcgcaagtctggc
cacctggtaccagccagctggaagctgcaggtgatcaaacagctggcctatgccctcaac
tatctggaagacaaaggcctcccccatggcaatgtctcagcccggaaggtgctcttggct
cgggagggggctgacgggaacctgcccttcatcaagttgagtgaccctggtgtcagcccc
actgtgctgagcctggagatgctcactgacaggatcccctgggtggcccctgagtgtctc
caggaggcccggacccttggcttggaagctgacaagtggggtttcggtgccacagtctgg
gaagtgttcagcgggatcccgatgcccatcagtatcctggatcctgccaagaagctccag
ttttacgaggaacggcagcaccttcctgcccccaagtggatggagctggccacactgatc
caacagtgcatggcctatgagccaggccagaggccctccttccgcgccatcatccgtgac
ctgaacagcctcatcacttcagattatgagctcctctcagaccccacacctggtgccttg
gcgccccgtgatgggctgtggaatggcgcccagctctacgcctgccaggaccctaccatt
tttgaggagagacatctcaagtacatctcacagctaggcaagggcaactttggcagcgtg
gagctgtgccgctatgacccactgggcgacaacacgggggccctagtggctgtgaagcag
cttcagcacagcgggccagatcagcagagggacttccagcgggagatccagatcctcaaa
gccctccacagcgacttcattgtcaagtaccgcggtgtcagctatggcccgggccgccag
agcctgcggctggtgatggagtacctgcccagcggctgcctgcgcgacttcctgcagcga
caccgcgcgcgcctcgacgccagccgcctgctcctctacgcctcgcagatctgcaagggc
atggagtacctgggctcccgccgctgcgtgcaccgcgacctggcggcccgtaacatcctg
gtggagagcgagacgcacgtcaagatcgccgactttggcctcgccaagctgctgccgctc
gacaaagactactacgtggtccgcgagcccggccagagccccatcttctggtacgcccca
gagtccctctctgacaacatcttctcgcgtcagtcggacgtctggagcttcggggtcgtc
ctgtacgagcttttcacctacggcaacaagaattgcagcccctcagccgagttcctccgg
atgatgggatgggagcgagacgtccccgccctctgccgcctcctggagctgctggctgag
ggccagaggctgcccgcgcctcctgcctgccccggtgaggttcatgagctcatgaagctg
tgctgggccccgagcccgcaagaccggccaacattcagtgccctgggcccccagctggat
acactgtggagtggaagccggggggtagcatag
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integrated database retrieval system
