Puma concolor (puma): 112854345
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Entry
112854345 CDS
T08890
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo04010
MAPK signaling pathway
pcoo04020
Calcium signaling pathway
pcoo04151
PI3K-Akt signaling pathway
pcoo05200
Pathways in cancer
pcoo05216
Thyroid cancer
pcoo05223
Non-small cell lung cancer
pcoo05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112854345 (RET)
04020 Calcium signaling pathway
112854345 (RET)
04151 PI3K-Akt signaling pathway
112854345 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112854345 (RET)
05230 Central carbon metabolism in cancer
112854345 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
112854345 (RET)
05223 Non-small cell lung cancer
112854345 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcoo01001
]
112854345 (RET)
Enzymes [BR:
pcoo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
112854345 (RET)
Protein kinases [BR:
pcoo01001
]
Receptor tyrosine kinases (RTK)
RET family
112854345 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD1
RET_CLD4
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
112854345
NCBI-ProteinID:
XP_025773597
UniProt:
A0A6P6HD24
LinkDB
All DBs
Position
Unknown
AA seq
1249 aa
AA seq
DB search
MARAGQDHGELAKSLLAELDSSPLLMGKLAELLGPGLACSFELAGDNPPRHSGAKAVDGD
AKNSQVLLASTLLTRARSVGAERMSSSCCIESHDLSSADMQRPLTVSPSTTEDFVGEQSL
SQQAGPPGHAVPSSDPPSEPAFRDVAMLALGQDAAMAPLGLYFARDAYWEKLYVDQPAGM
PLLYVHALRDMPEEVPTFRLGQHLYGIAYRARLHENDWIRIEEDTGLLYLNRSLDHSTWD
KLSIRNGGFPVLTIYLQVFLSPTSLREGECQWPGCARVYFSFVNTSFPACGSLKPRELCF
PETGVSFRIRENRPPGTFHQFRLLPVQFLCPNISVAYRLLEGENLPFHCAPDSLEVSTRW
PLDRELREKYELVAACTVRVGARKEEVVMVPFPVTVYDEDDSAPTFLGGIDTASAVVEFK
RKEGTVVAKIRVFDADVVPASGELLKRYTNTLLSGDAWVLQTFRIEHSPNETLAQANGSF
VRATVHDYRLVLNRSLPISENRSLQLTVLVNDSDFQGPGEGTLFLHFNVSVLPVSLHLPS
TYIFTVSRRARRFAQIGKVCVENCQEFSGIHVQYRLQLSSTNCSVLGVVTSAEDTTGNLF
VNDTEALQRPNCSQLRYTVVAADRPTRKQTQALLVVTVEGTYVAEEPGCPLSCAVSKRRP
ECEECGGLGSLTGRCEWRQGDGKGITRNFSTCSPSIKTCPDGHCDAVESRNVNICPQDCL
RGGSIIGGHEPGERWGIKAGFGICNCFPEEKKCFCEPEDSQEPLCDELCRTVIAAAVLFS
FVVSMLLSTFCIHRYHKNAHKPPIASAEMTFRRPAQAFPVSYSSSGARRPSMDSMENQVS
VDAFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENAS
PSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLFLIVEYAKYGSLRGFLRESRKAGPG
YVGSGGSRSSSYLDNPEERALTMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVAEG
RKMKISDFGLSRDVYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIV
TLGGNPYPGIPPERLFNLLKTGYRMERPDNCSEEMYGLMLQCWKQEPDKRPVFADISKDL
EKMMVKNRDYLDLAASTPSDSLLYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMS
DPNWPEESPVPLTRADGTNTVCPRYANDSVYANWMVSPSAAQLMDAFDS
NT seq
3750 nt
NT seq
+upstream
nt +downstream
nt
atggccagggctggccaggaccatggagagctggcgaagagcctgctggcggagctggac
agcagcccactgctcatggggaagttggctgagttgcttgggccgggactggcctgcagc
ttcgagctggctggagacaatcctccaaggcacagtggagccaaggctgtggacggtgac
gccaagaacagccaggttctactggcttctaccctgctgaccagggccaggagtgtgggt
gctgagagaatgtccagcagctgctgtattgagtctcatgacttaagctcagctgacatg
cagcggcccctcactgtgagccctagcaccactgaggactttgtcggggagcaaagcctg
tcccagcaggcagggccccctggccatgctgtgcccagctctgatcccccttctgagcct
gccttccgggacgtggccatgctggcgctggggcaggatgctgccatggctccgctggga
ctctacttcgccagggatgcttactgggagaaactctacgtggaccagccagctggcatg
cccctgctctacgtccatgccctgcgggacatgccggaggaggtgcccaccttccgcctg
ggccagcacctctacggcatcgcctaccgtgcaaggctgcatgagaacgactggattcgc
atcgaggaggacactggccttctctaccttaaccggagcctggatcacagcacctgggac
aagctcagcatccgcaatggcggcttccctgtgctcaccatctacctccaggtcttcctg
tcacctacatccctgcgtgagggcgagtgccaatggcccggctgtgcccgtgtgtacttc
tcctttgtcaacacctccttcccggcttgtggttccctcaaaccccgggagctctgcttt
cctgagacaggtgtctccttccgcatcagagagaataggcctcctggcactttccaccag
ttccgcctgctgcctgtgcagttcctctgccccaacatcagcgtggcctacaggctccta
gaaggtgagaacctgcccttccactgcgccccggacagcctggaggtgagcacgcgctgg
cccctggatcgcgagctgcgggagaagtacgagctggtggctgcttgcacggtgcgcgtc
ggcgcacgcaaggaggaggtggtgatggtacccttccccgtgaccgtgtatgatgaggac
gactcggcgcccaccttcctcgggggcatcgacaccgccagcgctgtggtggagttcaag
aggaaggagggcactgtggtggccaaaatacgtgtcttcgatgcagacgtggtgccggca
tccggggagctcctgaagcgatacacaaacacactactctctggggatgcctgggtcctc
cagacattccgtatcgagcactcccccaacgagaccttggcccaggccaacggcagcttt
gtgcgggcaactgtgcatgactacaggctggttctcaaccggagcctccccatctcggag
aaccgctccctgcagctgaccgtgctggtcaatgactcggacttccagggccccggggag
ggcaccctcttcctccacttcaacgtgtccgtgctgcctgtcagcttgcacttgcccagc
acctacatcttcactgtgagcaggcgggcccgccgctttgcccagattgggaaagtctgt
gtggaaaactgccaggagttcagcggcatccacgtgcagtacaggctgcagctctccagc
accaactgcagtgtcctgggggtggtcacctcagccgaggacaccacagggaaccttttc
gtgaacgacacagaagccctgcagcggcccaattgctctcaactccggtacacggtagtg
gctgccgaccggccaacccgcaagcagacccaggccctgctggttgtcaccgtggagggg
acatatgtggctgaggagccaggctgccccctgtcctgtgcagtcagcaagagacgccct
gaatgtgaggagtgcggtggcctgggctctctgacgggcaggtgcgagtggagacaggga
gatggcaaaggaatcaccaggaacttctccacctgctcccccagcatcaagacctgcccc
gacggccactgtgatgccgtggagagcagaaatgtcaacatctgcccccaggactgcctc
cggggcggcagcatcattggtgggcatgagccaggggagcgctgggggattaaagctggc
ttcggtatctgcaactgtttcccagaggagaagaagtgcttctgcgaacctgaagacagc
caggagccgctgtgtgacgagctctgccgcacggtgatcgcagccgctgtgctcttctcc
ttcgtcgtctccatgctgctctccaccttctgcatccaccgctaccacaagaatgcccac
aagccacccattgcctctgctgagatgaccttccgccggcctgcccaggccttcccggtc
agctactcctcgtccggcgcccgccggccctctatggactccatggagaaccaggtctct
gtggacgccttcaagatcccggaggatccaaagtgggaatttcctcgaaagaacttggtt
cttgggaaaaccctgggagaaggcgaatttggaaaagtggttaaggcgacagccttccgg
ctgaaaggcaaagcagggtacacaaccgtggccgtgaagatgctgaaagagaatgcttcc
ccaagtgagctgcgggacctgctgtcagagttcaacctcctgaagcaggtcaaccaccca
catgtcatcaagctgtatggggcctgcagccaggacggcccgctcttcctcattgtggag
tatgccaagtacggttccctgcggggcttcctccgagagagccgcaaggcggggcccggc
tacgtgggcagcggaggcagccgcagctccagctacctggacaaccccgaggagcgggcc
ctgaccatgggcgacctcatctccttcgcctggcagatctctcgggggatgcggtacctg
gctgagatgaagcttgtccatcgggacttggcagccagaaatgtcctggtagctgagggg
cggaagatgaagatttcagattttggcctgtcccgagacgtttatgaagaggattcctat
gtgaagaggagcaagggtcggattccagtcaaatggatggcaattgagtctcttttcgat
catatctacaccacccaaagtgatgtgtggtcctttggtgtcctgctgtgggagattgtg
actctggggggcaacccctaccctgggatccctccggagcggcttttcaacctcctgaag
acaggctaccggatggagaggcctgacaactgcagtgaggagatgtacggtctcatgctg
cagtgttggaagcaggaaccagacaagaggccagtgtttgctgacatcagcaaagacctg
gaaaagatgatggttaagaacagagactacttggacctggctgcctccaccccatccgac
tccctgctttatgacgacggcctctcggaggaggagacgcccctggtggactgtaataat
gctcccctccctcgagccctcccctccacgtggattgaaaacaaactctatggcatgtca
gacccgaactggcctgaagagagtcctgtaccactcacgagagctgatggcactaacact
gtgtgtccaagatatgcaaatgatagtgtatatgctaactggatggtttcaccctcagcg
gcacaattaatggacgcatttgatagttaa
DBGET
integrated database retrieval system
