Puma concolor (puma): 112854661 Help Entry 112854661         CDS       T08890                                  Symbol HK1 Name (RefSeq) hexokinase-1 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism pcoo  Puma concolor (puma) Pathway pcoo00010   Glycolysis / Gluconeogenesis pcoo00051   Fructose and mannose metabolism pcoo00052   Galactose metabolism pcoo00500   Starch and sucrose metabolism pcoo00520   Amino sugar and nucleotide sugar metabolism pcoo01100   Metabolic pathways pcoo01200   Carbon metabolism pcoo01250   Biosynthesis of nucleotide sugars pcoo04066   HIF-1 signaling pathway pcoo04910   Insulin signaling pathway pcoo04930   Type II diabetes mellitus pcoo04973   Carbohydrate digestion and absorption pcoo05230   Central carbon metabolism in cancer Module pcoo_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate pcoo_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose pcoo_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:pcoo00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     112854661 (HK1)    00051 Fructose and mannose metabolism     112854661 (HK1)    00052 Galactose metabolism     112854661 (HK1)    00500 Starch and sucrose metabolism     112854661 (HK1)    00520 Amino sugar and nucleotide sugar metabolism     112854661 (HK1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     112854661 (HK1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     112854661 (HK1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     112854661 (HK1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     112854661 (HK1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     112854661 (HK1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     112854661 (HK1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pcoo04131]     112854661 (HK1) Enzymes [BR:pcoo01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      112854661 (HK1) Membrane trafficking [BR:pcoo04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     112854661 (HK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 UvrD-helicase Motif Other DBs NCBI-GeneID:  112854661 NCBI-ProteinID:  XP_025773999 UniProt:  A0A6P6HE15 LinkDB All DBs Position Unknown AA seq 842 aa AA seqDB search MRLSDETLIDIMTRFKKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS SFRILRVQVNHEQNQNVHMESEIYDTPENIVHGSGSQLFDHVAECLGDFMEKKKIKDKKL PVGFTFSFPCRQSKIDEAILITWTKKFKASGVEGMDVVKLLNKAIKKRGDYDANIVAVVN DTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDG SLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPEL LTRGKFKTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCISVQHVCTIVSFRSANLVAA TLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVRFLLSESG SGKGAAMVTAVAYRLAEQHRQIEETLAHFRLTKDMLLEVKKRMRAEMDMGLRKQTHEKAV VKMLPSFVRSTPDGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQ GTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCKQTSLDAGILITWTKGFKATDC VGHDVATLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYME EMKNVEMLEGDEGRMCINMEWGAFGDNGCLDDIRTLYDRLVDEYSLNAGKQRFEKMISGM YLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFQTKYLSQIESDRLALLQVRAILQQLG LNSTCDDSILVKTVCGVVSKRAAQLCGAGMAAVVDKIRENRGLDHLSVTVGVDGTLYKLH PQ NT seq 2529 nt NT seq  +upstreamnt  +downstreamnt atgcggctctccgatgaaactctgatagatatcatgactcggttcaagaaggagatgaag aatggcctctcccgggattttaatccaacagccacagtgaagatgttgccaacgtttgta aggtctattcctgatggttcagaaaagggagatttcattgccctggatcttggcgggtct tcctttcgaattctgagggtgcaagtgaatcatgagcaaaaccagaatgttcacatggag tccgagatttatgacaccccggagaacatcgtgcacggcagtggaagccagcttttcgat cacgtcgccgagtgcctgggagacttcatggagaagaagaaaatcaaggacaagaaatta cctgtgggattcacgttttccttcccttgtcggcagtccaaaatagacgaggccatcctg atcacctggacaaagaaatttaaagcgagcggagtggagggaatggatgtggtgaagctg cttaacaaagccatcaaaaagcgcggggactacgatgccaacattgtggctgtggtgaac gacacggtggggaccatgatgacctgtggctacgacgaccagcagtgcgaagtcggcctc atcattggcactggcaccaacgcgtgctacatggaggaactgaggcacattgacctggtg gaaggcgacgagggcaggatgtgcatcaacacggagtggggggcctttggggacgacggg tccctcgaagacatccgcaccgagttcgaccgggagatagaccgtggctctctcaaccct gggaagcagctgtttgagaagatggtgagtggcatgtacttgggggagctggttcgactg atcctggtcaagatggccaaggagggcctcttatttgaaggacggatcaccccggagctg ctcaccagggggaagttcaagaccagtgatgtgtcagccattgaaaagaataaggaaggc ctccacaatgccaaagaaatcctgacccgcctgggagtggagccatctgatgacgactgt atttcagtccagcacgtgtgtaccattgtctcatttcgctctgccaacctggtggctgca acgctgggcgccatcttgaaccgccttcgagataacaagggcacacccaggctgcggacc acggttggtgtcgacgggtctctttacaagacgcacccacagtattcacgacgtttccac aagactctgaggcgcttggtgcccgactccgatgtgcgcttcctcctctcggagagcggc agcgggaagggggccgccatggtcaccgcggtggcctaccgcctggccgagcagcaccgg cagatcgaggagaccctggcccacttccgcctcaccaaggatatgctgctggaggtgaag aagagaatgcgggccgagatggacatgggcctgaggaaacagacgcacgaaaaggccgta gtcaagatgctgccctccttcgtccggagcactccagacgggaccgagcatggtgacttc ttggcccttgatcttggaggaacgaatttccgtgtcttactggtgaaaatccgcagtggg aaaaagagaacggtggaaatgcacaacaagatctatgccattcccattgaaatcatgcag ggcactggggaagagctgtttgaccacatcgtctcctgcatctccgacttcctggactac atggggatcaaaggccccagaatgcctctcggcttcacgttctcattcccctgcaagcag acgagcttggatgcgggaatcttgatcacctggacgaagggttttaaggcaaccgactgc gtggggcacgatgtagcaaccttactaagggatgcgatcaaaaggagagaggaatttgac ctggacgtggtggctgtggtcaatgacacggtgggcaccatgatgacctgtgcttatgaa gagcctacctgcgaggttggactcatcgtagggactggcagcaacgcctgctacatggaa gaaatgaagaatgtcgagatgctggagggggacgaggggcgaatgtgcatcaacatggag tggggtgcctttggggacaacgggtgtctcgatgacatcagaactctctatgacagactg gtggatgaatattctctaaacgctggaaaacaaaggtttgagaagatgatcagtggtatg tacctgggtgagatcgtccgcaacatcttgatcgacttcaccaagaaggggttcctcttc cgagggcagatctctgagccgctgaagactcgtggcatttttcagaccaaatatctctcc cagattgagagtgaccggttagcactgctccaggtccgggccatcctccagcagctgggc ctgaatagcacctgtgacgacagtatcctcgtcaagaccgtgtgcggggtggtgtccaaa cgggccgcgcagctgtgcggtgcgggcatggccgccgtggtggacaagatccgcgagaac agagggctggaccatctcagtgtgactgtgggggtggatggaacactctacaagcttcat ccgcagtga

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