Puma concolor (puma): 112855235
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Entry
112855235 CDS
T08890
Name
(RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo04120
Ubiquitin mediated proteolysis
pcoo04144
Endocytosis
pcoo04330
Notch signaling pathway
pcoo04668
TNF signaling pathway
pcoo04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
112855235
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
112855235
04668 TNF signaling pathway
112855235
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
112855235
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
112855235
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pcoo04131
]
112855235
04121 Ubiquitin system [BR:
pcoo04121
]
112855235
Enzymes [BR:
pcoo01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
112855235
Membrane trafficking [BR:
pcoo04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
112855235
Ubiquitin system [BR:
pcoo04121
]
Ubiquitin ligases (E3)
HECT type E3
112855235
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
Motif
Other DBs
NCBI-GeneID:
112855235
NCBI-ProteinID:
XP_025774595
UniProt:
A0A6P6HFS5
LinkDB
All DBs
Position
Unknown
AA seq
750 aa
AA seq
DB search
MKLEKVVVTLQLVGDKEPTETIGDLSVCLDGLQLESEVVNNGETTCSECVSQTNDVSRPK
DEAKTHPNGSDEPEDSGTGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPLTPCRPASVN
GSPSATSENDGSSMDSLPPTNINXNTSEGATSGLIIPLNISGGSGPRPLNPVPQDPLPSG
WEQRVDQHGRVYYIDLIERRTMWNRPEPLPPGWEQWVDNMGHIYYVDNFTRTTTWQRPTL
ESIRNYEQWQLQCSQLQGAMQQFNQRFIYGNQDLFSTSQNKEFDPLLSLPPGWEKRTDGN
GRVYFVNHNSCITQWEDPRSQGKLNEKLLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRT
GKSALDNRPPIAYVRDFKANVQYFRFWCQQLVMPQHIKITGTRKTLFEDSFQQIMSFNPQ
DLRRRLWVIFPGKEGLDYGGVARERFFVLSSEVLNPMYCPFEYAGKDNYCLQINPASYIN
PDHLKYFCFIGRLIAMALFHGKFIDTDFXXPFYKHILNKPLELKDLESIDPEFYNSLIWV
KENNIEERGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENEEEYIRMVAEXKLSXGVE
EQTQAFFEGFNEILPRKYLQYLDAKELEVLLRGMQEIHLNDWQRHAIYHHYTRTSKQIML
FGQFVKEIDNEKRMRLLQFVTGICXLPVGGFADLMGRNGPQKFCTEKVGKENWLPRSHTC
FNHLDLPPYKSYEQLKEKLLFAIEETEGFG
NT seq
2253 nt
NT seq
+upstream
nt +downstream
nt
atgaaacttgagaaagtagttgtgactttacagcttgtaggtgacaaagagccaacagag
acaataggagacttgtcagtttgtcttgatgggctgcagttagagtctgaagttgttaac
aatggtgaaactacatgttcagaatgtgtttcacagactaatgatgtctccagacccaag
gatgaagcaaaaacacatccaaatggatcagatgaacctgaggattcagggactggtgaa
aataggaaggtcaatgggaataattctccatcactctcaaatggcggttttaaaccttct
aggcctcccagaccttcacgaccacctccacttaccccatgtagaccagcatctgtcaat
ggttcaccatctgccacttctgaaaatgatggatccagtatggactctctgccaccaaca
aatataaattgaaatacatctgaaggagcaacatctggattaataattcctcttaatata
tctggaggctcaggccctaggccattaaatcctgtacctcaagatcccctaccatctggc
tgggagcagagagtggaccagcatgggcgagtttactacatagatcttattgaaagaaga
acaatgtggaatagaccagaacctctacctcctggctgggaacagtgggttgacaacatg
ggacatatttattatgttgacaatttcacaagaacaacaacatggcagaggccaacattg
gaatccatccggaactatgaacagtggcagctccaatgtagtcagcttcaaggagcaatg
cagcagtttaaccagagattcatttatgggaatcaggatttgtttagtacatcacaaaat
aaagaatttgatccccttctttccctgcctcctggatgggagaagagaacagacggcaat
ggtagagtatatttcgtcaaccacaactcttgtattacacaatgggaggaccccagaagt
caaggtaaattaaatgaaaagctcttacctgaaggttgggaaatgagattcacagtagat
ggaattccatattttgtggaccacaatagaagaacaaccacctatattgacccccgcact
ggaaaatctgctctagacaatagaccaccgatagcctatgtacgggacttcaaggcaaat
gttcagtatttccggttctggtgtcagcaacttgtgatgccacagcacataaagattaca
gggacaagaaaaacattgtttgaagattcctttcagcagataatgagcttcaatccccaa
gatctgcgaagacgtttgtgggtgatttttccaggaaaagaaggtttagattatggaggt
gtagcaagagagaggttctttgttttgtcaagcgaggtgttgaaccccatgtattgcccg
tttgaatatgcagggaaggataactactgcttgcagattaatcctgcttcttacatcaat
ccagatcacctgaaatatttttgttttattggcaggcttattgccatggctttgttccat
gggaaattcatagacacagattttnnnnnnccattctataagcatatattgaacaaacca
cttgaactcaaggatttagaatctattgatccagaattttacaattctctcatctgggtt
aaagaaaacaatattgaggaacgtggtttggaaatgtacttctctgtcgataaagaaatt
ttaggtgaaatcaagagtcatgatttgaaacctaatggtggcaatattcttgtgacggaa
gaaaatgaagaggaatatatcagaatggtagctgaatgaaagttgtcttgaggtgttgaa
gaacagacacaagctttctttgagggctttaatgaaattcttccccgaaaatatttgcaa
tacttggatgcaaaggaattagaggtccttttacgtggaatgcaagagattcatttgaat
gactggcaaagacatgccatctaccatcattacactaggacaagcaaacaaattatgttg
tttgggcagtttgttaaagaaattgataatgagaagagaatgagacttctgcaatttgtt
actggaatctgctgattgccagttggaggatttgctgacctcatggggagaaatggacca
cagaaattctgcactgaaaaagttgggaaagaaaactggttacccagaagtcatacctgt
tttaaccacctggacctgccaccctacaagagctatgagcaactgaaggaaaagctgtta
tttgctattgaagaaacagaaggatttggatga
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