Puma concolor (puma): 112860292 Help Entry 112860292         CDS       T08890                                  Symbol HK3 Name (RefSeq) hexokinase-3   KO K00844   hexokinase [EC:2.7.1.1] Organism pcoo  Puma concolor (puma) Pathway pcoo00010   Glycolysis / Gluconeogenesis pcoo00051   Fructose and mannose metabolism pcoo00052   Galactose metabolism pcoo00500   Starch and sucrose metabolism pcoo00520   Amino sugar and nucleotide sugar metabolism pcoo01100   Metabolic pathways pcoo01200   Carbon metabolism pcoo01250   Biosynthesis of nucleotide sugars pcoo04066   HIF-1 signaling pathway pcoo04910   Insulin signaling pathway pcoo04930   Type II diabetes mellitus pcoo04973   Carbohydrate digestion and absorption pcoo05230   Central carbon metabolism in cancer Module pcoo_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate pcoo_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc pcoo_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:pcoo00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     112860292 (HK3)    00051 Fructose and mannose metabolism     112860292 (HK3)    00052 Galactose metabolism     112860292 (HK3)    00500 Starch and sucrose metabolism     112860292 (HK3)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     112860292 (HK3)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     112860292 (HK3)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     112860292 (HK3)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     112860292 (HK3)   09154 Digestive system    04973 Carbohydrate digestion and absorption     112860292 (HK3)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     112860292 (HK3)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     112860292 (HK3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pcoo04131]     112860292 (HK3) Enzymes [BR:pcoo01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      112860292 (HK3) Membrane trafficking [BR:pcoo04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     112860292 (HK3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  112860292 NCBI-ProteinID:  XP_025779351 UniProt:  A0A6P6HV56 LinkDB All DBs Position Unknown AA seq 953 aa AA seqDB search MPHIEREELTPEESDQLLLPGGRPPLWKHMESIGAVGLQQREGVPSCSQKGLPCPSDSSE LVLECLQQFKVTQTQLQQIQTSLLGSMEQALGGQASPASAVRMLPTYVGSTPHGTEQGDF LVLELGATGASLRVLWVTLMGTEGHRMEPRSQEFVIPPEVMLGPGHQLFDFAAHCLSEFL DAFPVSTQDLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGHDVVQLLRDAIKRQGA YSIDVVAVVNDTVGTMMGCEPGVGPCEVGLVVDTGTNACYMEEARHVAVLDEDRGRVCVS VEWGSFGDDEALGPVLTTFDHALDRESLNPGAQRFEKMIGGLYLGELVRLVLAHLAQRGA LFGGCTSPALLSRGSILLQHVTEMEDPLAGAARVHAILQDLGLSVGASDAELVRYVCTAV FTRAARLCAAALAAVLSRLQHSREQQMLQIAVATGGRVFERHPSFLSILQETVMLLVPEC DVSFIPSVDGGGRGVAMVTAVAARLAAHRRLLEETLAPFRLNREQLAAVQAQMQEAMAKG LQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFRVLLVRVTAGGVQITSQVYSIPE CVAQGSGQQLFDHIVDCIVDFQQKQGLSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGFN ASDCEGQDVVCLLREAIERKQAVKLNVVAIVNDTVGTMMSCGYEDPRCEVGLIVGTGTNA CYMEELRNVASVAGDSGHMCINMEWGAFGDDGSLGLLRTCFDANVDQASINPGKQSFEKM ISGMYLGEIVRHILLHLTSLGVLFRGQQTQCLQTRDIFKTKFLSEIESDSLALRQVRAIL EDLGLPLTSDDALMVLEVCQAVSQRAAQLCGAGVAAVVEKIRENRGLEELTVSVGVDGTL YKLHPHFSGLVAATVRELAPRCAVTFLQSEDGSGKGAALVTAVACRLAQMDHV NT seq 2862 nt NT seq  +upstreamnt  +downstreamnt atgcctcacattgagagagaagagctgacgcccgaggaaagtgaccaactgcttctccca ggtggccgccccccattgtggaaacacatggaatccattggggcagtagggttgcagcaa agggaaggagttcctagctgctcccagaagggcttgccttgcccctcagacagctctgag ctggtgctggaatgcctacagcaattcaaggtaacacagacacagctgcagcagatccaa accagcctcctgggctctatggagcaggcactaggggggcaggccagccctgcttccgct gtccggatgctgcccacatatgtggggtccaccccacatggcactgagcaaggagatttt ttggtgctggagctgggggccacaggggcctcactgcgtgttctgtgggtgaccctgatg ggcactgaaggacacaggatggagccccggagccaggagtttgtgatccccccagaggtg atgctgggtcctggtcatcagctctttgactttgctgcccactgcctgtctgagttcctg gatgcattccctgtgagcactcaggatctgcagcttgggttcagcttctccttcccttgt caccagacaggactggacaggagcaccctcatttcctggaccaaaggttttaggtgcagt ggtgtggaaggccacgacgtggtccagttactacgagatgccatcaagaggcagggggcc tacagcatcgatgtggttgccgtggtgaatgacacagtgggcaccatgatgggctgcgag ccaggggttgggccttgtgaggtcgggcttgttgtagacactggcaccaatgcatgttac atggaggaggcaaggcatgtggcggtgctggatgaggaccggggtcgtgtctgcgtcagc gttgagtggggctccttcggcgatgatgaagccctgggaccagtgctgaccacatttgac catgccttggaccgagagtccctgaatcctggtgcccaaaggtttgagaagatgattggg ggcttgtacctgggtgaactggtgaggcttgtgttggctcacctggcccagcgaggagcc ctctttggcggctgcacctcccctgccctgctgagccgaggcagcattctcctacagcat gtgactgagatggaggaccccttggccggggcagcccgtgtgcatgctatcctgcaggac ttgggcctgagcgtgggagcctcggatgctgagcttgtgcggtacgtgtgcacagccgtg tttactcgggctgcccggctctgtgctgctgccctggctgctgttctctcccgcctccaa cacagccgggagcagcagatgcttcagatcgctgtggccaccggaggccgagtgtttgag cgacatcccagtttcctcagcatcctgcaggagaccgtgatgctcctggtccctgaatgt gacgtctccttcattccctctgtggacgggggcggccggggcgtggcaatggtgactgct gtggctgcccgcctggctgctcaccgacgcctgctggaagagaccctggcaccattccgg ttgaaccgtgaacagctggcagcagtgcaggcacagatgcaggaggccatggccaagggg ctccaaggggaggcctcatccctccgaatgctgcccacttatgtacgggccacgcctgat ggcagtgagcgtggggacttcctggccctggaccttgggggcaccaacttccgggtcctc ctggtacgtgtaactgcaggaggtgtgcagatcaccagccaggtctactccatcccagag tgtgtggcccagggctctggacagcagctcttcgaccacattgtggactgcattgtggac ttccagcagaagcaaggcctgagtgggcagagcctccccctgggtttcaccttctccttc ccatgcaggcagcttggcctggatcagggcatcctcctaaactggacaaagggtttcaat gcatcagactgtgagggccaagatgttgtgtgtctgctgagggaagccattgagcgaaaa caggcagtgaagctgaatgtggttgccattgtcaatgacacggtggggaccatgatgtcc tgtggctatgaggatccccgttgtgaggtcggcctcatcgttggaactggcactaatgcc tgctacatggaggaacttcggaatgtggcaagtgtggctggggattcaggccacatgtgc atcaatatggagtggggagcctttggggatgatggctctctgggcttgctcagaacctgc tttgatgcaaatgtggaccaggcatccatcaaccctggcaagcagagttttgagaagatg atcagtggcatgtaccttggggagatcgtccgccacattctcttgcatttgaccagcctt ggagttctcttccggggccagcagacccagtgccttcagaccagggacatcttcaagacc aagtttctctctgagattgaaagtgacagcctggctctgaggcaggtccgagccatcctg gaggatctgggactgcccctgacctcagatgatgccctgatggttctggaggtgtgccag gctgtgtctcagcgggctgcccagctctgtggggcgggtgtggctgctgtggtggagaag atccgtgagaaccggggcctagaagagttgactgtatccgtgggggtggatgggaccctc tacaagctgcacccccacttctccggcctggtggcagccacagtcagggagctagcccct cgctgtgcggtcaccttcctgcagtcagaagatgggtctggcaaaggtgcagccctggtc actgcggttgcctgtcgccttgcccagatggaccatgtttga

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