KEGG   Puma concolor (puma): 112860403
Entry
112860403         CDS       T08890                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase isoform X1
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
pcoo  Puma concolor (puma)
Pathway
pcoo00670  One carbon pool by folate
pcoo00790  Folate biosynthesis
pcoo01100  Metabolic pathways
pcoo01240  Biosynthesis of cofactors
pcoo01523  Antifolate resistance
pcoo04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:pcoo00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    112860403 (DHFR)
   00670 One carbon pool by folate
    112860403 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    112860403 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    112860403 (DHFR)
Enzymes [BR:pcoo01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     112860403 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 112860403
NCBI-ProteinID: XP_025779512
UniProt: A0A6P6HUJ2
LinkDB
Position
Unknown
AA seq 200 aa
MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINIVLSRDLKEPPQGAHFLAKSLDDALELTEQPELAHKVDMVWVVGGSS
VYKINKEIDASCVFSKEAMNRPGHVRLFVTRIMQEFESDTFFPEIDLEKYKLLPEYPGVL
SDIQEEKSIKYKFEVYEKNN
NT seq 603 nt   +upstreamnt  +downstreamnt
atggttcgtccgctaaactgtatcgtcgctgtgtcccagaacatgggcatcggcaagaac
ggggacctgccctggccgccgctcaggaatgaattcaagtatttccaaaggatgaccaca
acctcatccgtagaaggtaaacagaatttggtgattatgggtagaaagacatggttctct
attccggagaagaatcgacctttaaaggacagaattaatatagttctcagtagagacctc
aaggaacctccacaaggagctcattttcttgccaaaagtctggatgatgccttagaactt
actgagcaaccagaattagcacataaagtggacatggtttgggtagtgggaggcagttct
gtttataagataaataaagaaattgatgcctcttgtgttttttcaaaggaagccatgaac
aggccaggccacgttagactatttgtgacaaggattatgcaggagtttgaaagtgacaca
ttttttccagaaattgatttggagaaatataaacttctcccagaatacccaggtgttctt
tctgatatccaggaggagaaaagcattaagtacaaatttgaagtatatgagaagaacaat
taa

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