Puma concolor (puma): 112864237
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Entry
112864237 CDS
T08890
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo04137
Mitophagy - animal
pcoo04140
Autophagy - animal
pcoo04141
Protein processing in endoplasmic reticulum
pcoo04210
Apoptosis
pcoo04932
Non-alcoholic fatty liver disease
pcoo05010
Alzheimer disease
pcoo05012
Parkinson disease
pcoo05014
Amyotrophic lateral sclerosis
pcoo05020
Prion disease
pcoo05022
Pathways of neurodegeneration - multiple diseases
pcoo05160
Hepatitis C
pcoo05162
Measles
pcoo05168
Herpes simplex virus 1 infection
pcoo05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
112864237 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
112864237 (EIF2AK3)
04137 Mitophagy - animal
112864237 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
112864237 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
112864237 (EIF2AK3)
05162 Measles
112864237 (EIF2AK3)
05168 Herpes simplex virus 1 infection
112864237 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
112864237 (EIF2AK3)
05012 Parkinson disease
112864237 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
112864237 (EIF2AK3)
05020 Prion disease
112864237 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
112864237 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112864237 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
112864237 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcoo01001
]
112864237 (EIF2AK3)
Enzymes [BR:
pcoo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
112864237 (EIF2AK3)
Protein kinases [BR:
pcoo01001
]
Serine/threonine kinases: Other
PEK family [OT]
112864237 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
OATP
Motif
Other DBs
NCBI-GeneID:
112864237
NCBI-ProteinID:
XP_025783094
UniProt:
A0A6P6I5P2
LinkDB
All DBs
Position
Unknown
AA seq
1115 aa
AA seq
DB search
MERATRPGPLVRALLLLLQLLLGLAAGTVAAGRAPDLPAPKVEAAFGLGAAAAPTSAARV
PAAGAVAAAEVTVEDAEAVPAAAVEQEPREPEPDDEAELQPRGRSLVIISTLDGRIAALD
PENRGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVE
SLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDNDEMEQEDILLLQR
SQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTLKPSGNKEGSKIISDVEE
QEAAMMDTVIKVSVADWKVMAFNKKGGHLEWEYQFCTPIASAWLVKDGKVIPISLFDDTS
YASNDEVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALESVNNE
YAIVPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGY
YLPYYKRERSKRSTQITVRFLDNPNYNKNIRKKDPVLLLHWWKEIVGTILFCIIATTFIV
RRLFHPHPHRQRKESETQCQTESKYDSVSGDAKDSSWNDIKNSGYISRYLTDFEPVQCLG
RGGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLDHPGIVRYFNAWLE
APPEKWQEKMDEIWLKDESTDWPLSSPSPVDGPSVKIRRMDPFSTKEHIEIIAPSSQRRS
FSVGISCGQTSSSESQFSPLELSGTNHGDTSESVDAAYNLQDSCLTECDMEDGTMDGNEE
GHSFELCPSEASLYGRSRERTSSSIVFEDSGCDNASRKEEHKTDRLHIGNHCANKLTPFK
HSSSKSSSEPTFSISPPRPTTLSLDLTKNTAEKLQPSSPKVYLYIQMQLCRKENLKDWMN
SRCTIEERERSMCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTVDDVVKVGDFGLVTA
MDQDEEEQMVLTPMPACARHTGQVGTKLYMSPEQIHGSNYSHKVDIFSLGLILFELLYPF
STQMERVRILTDVRNLKFPPLFTQKYPREYVMVQDMLSPSPMERPEATNIIENAVFEDLE
FLGKTVLRQRSRSMSSSGTKHSRHCSSSWSPLPST
NT seq
3348 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccacccgcccggggccgctcgtgcgggcgctgctgctgctgctgcagctg
ctgctggggctcgcggctggcacggtggccgcagggcgcgcccccgacctccccgcgccg
aaggtggaggcggcgttcggcctgggcgccgcggccgctcccacttcagcagcgcgggtg
ccggctgcgggggccgtggctgcggccgaggtgacggtggaggacgccgaagcagtgccg
gcggccgcggtcgagcaggagccgcgggagccggagcccgacgacgaggccgagctacag
ccgcgaggcagatcattagtgattatcagcactttagatgggcgaattgctgccttggat
cctgagaatcgtggtaaaaaacagtgggatttggatgtgggatccggctccttggtttca
tccagcctcagcaaaccagaggtatttgggaataagatgatcattccttccctggatgga
gacctctttcagtgggaccgggaccgtgagagcatggaaactgttccttttacagttgaa
tcgcttcttgaatcttcttataaatttggagacgatgttgttttggttggaggaaagtct
ctcactacctacggactcagtgcatatagtggaaaggtgaggtatatctgctcagctttg
ggttgtcgccagtgggataatgatgaaatggaacaagaagacatcctgcttctgcagcgc
tcccagaaaactgttagagctgttggacctcgcagtggcaatgagaagtggaatttcagt
gttggccactttgaacttcggtatattccagacatggaaactagagccggatttattgaa
agcaccttaaagcccagtgggaacaaagaagggtctaaaattatttcagatgtggaagaa
caggaagctgccatgatggacacagtgataaaggtgtcggttgcagactggaaggttatg
gcgtttaataagaagggaggacatctggaatgggaataccagttttgtactcccattgca
tctgcctggttggttaaggacggaaaagtcattcccatcagtctttttgatgatacaagt
tatgcatctaatgatgaggttttagaagatgaagaagacattgtagaagctgctcgagga
gccacagaaaacagcgtttacttgggaatgtacagaggtcagctgtatctgcagtcatca
gtcagaatttcagaaaagtttcctacaagtcccaaggccttggaatctgtcaataatgaa
tatgcaattgttcctttgccaacaatcaaatggaagcccttaattcattccccgtccaga
actcctgtcttggtagggtctgatgaattcgacaaatgtcttagcaacgataagttttct
catgaagagtacagcaacggtgcgctttcaatcttgcaatacccatatgataatggttat
tacctaccatactacaagagggagaggagcaaacggagcacacagatcacagtccgattt
ctcgataacccaaattacaacaagaacattcgcaaaaaggatcccgttctcctcttacac
tggtggaaagagatagtcggaactattctattttgtatcatagcaacaactttcatcgtg
cgtaggcttttccatcctcatcctcacagacaaaggaaggaatcggaaactcagtgtcag
actgaaagtaaatatgattctgtaagtggagacgccaaggacagtagctggaatgacata
aaaaattctgggtatatatcgcgatatctaacagattttgagccggttcagtgcctggga
cgcggtgggtttggagttgtctttgaagccagaaataaagttgatgactgcaattatgct
atcaagagaatccgtctccccaacagggaattggctcgggaaaaggtaatgcgagaagtt
aaagccttagccaagcttgaccatccaggaattgtgagatatttcaatgcttggttggag
gcaccaccagagaagtggcaagaaaaaatggatgaaatctggctgaaagatgaaagcaca
gactggccactcagctctcctagtccagtggatggaccatccgttaaaatacgcagaatg
gaccctttctctacaaaggaacatattgagatcatagctccttcttcacaaaggaggtct
ttttcagtagggatttcctgtggccagacaagttcatccgagagccagttctctccactg
gaattatcaggaacaaaccacggagataccagtgaatcagtggatgcagcctacaacctc
caggacagttgccttacagagtgtgatatggaagacggtaccatggacggcaatgaggag
gggcactcctttgaactttgtccttctgaagcttctctttatggaaggtcaagggagcga
acatcctcttctatagtgtttgaagattctggctgcgataatgcatccaggaaagaagag
cacaaaactgaccgcctgcatattggcaaccattgtgctaataaactgactcctttcaag
cattccagtagcaaatcttcttccgaacctaccttctctatttctcctccaagaccgacc
actttgagtttagatctcactaaaaacactgcagaaaagctccagcccagttcaccgaag
gtatatctttacattcagatgcagctgtgcagaaaggaaaacctcaaagactggatgaac
agtcggtgcaccatagaggagagagagaggagcatgtgtctgcacatcttcctgcagatc
gcagaggctgtagagtttctgcacagtaaagggctcatgcacagggacctcaagccttcc
aacatattctttacagtggacgatgtggtcaaggtcggggactttggactagtgactgca
atggaccaggatgaggaagagcagatggttctgaccccaatgccagcgtgtgccagacac
acaggacaagtagggaccaaactgtatatgagcccagagcagattcatggaagcaactac
tctcataaagtggacatcttttctttaggcctcattctgtttgaactgctgtacccattc
agcactcagatggagagagtcaggatcttaactgatgtaagaaatctcaaatttccacca
ctgtttactcagaaatatcctcgtgagtatgtgatggttcaagacatgctctctccatcc
cccatggaacggcctgaagctacgaacattattgaaaatgctgtatttgaagacttggaa
tttctaggaaaaactgtactcagacagaggtctcgttccatgagttcatcaggaacaaaa
cattcaagacactgcagcagctcctggagccctttgccaagcacttag
DBGET
integrated database retrieval system
